Search results for "Capacity"
showing 10 items of 999 documents
Near-normal aerobic capacity in long-term survivors after lung transplantation
2021
The clinical course of lung transplantation (LT) is diverse: some patients present chronic lung allograft dysfunction (CLAD) and progressive decline in pulmonary function, but others maintain normal spirometric values and active lives. Objectives The aim of this study was to elucidate whether long-term LT survivors with normal spirometry achieve normal exercise capacity, and to identify predictive factors of exercise capacity. Methods This was a cross-sectional multicentre study, where bilateral LT recipients who survived at least 10 years after LT, with normal spirometry, no diagnosis of CLAD and modified Medical Research Council dyspnoea degree ≤2 underwent cardiopulmonary exercise testin…
Dynamic determination of oxygenation and lung compliance in murine pneumonectomy.
2011
Thoracic surgical procedures in mice have been applied to a wide range of investigations, but little is known about the murine physiologic response to pulmonary surgery. Using continuous arterial oximetry monitoring and the FlexiVent murine ventilator, the authors investigated the effect of anesthesia and pneumonectomy on mouse oxygen saturation and lung mechanics. Sedation resulted in a dose-dependent decline of oxygen saturation that ranged from 55% to 82%. Oxygen saturation was restored by mechanical ventilation with increased rate and tidal volumes. In the mouse strain studied, optimal ventilatory rates were a rate of 200/minute and a tidal volume of 10 mL/kg. Sustained inflation pressu…
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample
2011
Lung function measures are heritable traits that predict population morbidity and mortality and are essential for the diagnosis of chronic obstructive pulmonary disease (COPD). Variations in many genes have been reported to affect these traits, but attempts at replication have provided conflicting results. Recently, we undertook a meta-analysis of Genome Wide Association Study (GWAS) results for lung function measures in 20,288 individuals from the general population (the SpiroMeta consortium). OBJECTIVES: To comprehensively analyse previously reported genetic associations with lung function measures, and to investigate whether single nucleotide polymorphisms (SNPs) in these genomic regions…
Some overdetermined problems related to the anisotropic capacity
2018
Abstract We characterize the Wulff shape of an anisotropic norm in terms of solutions to overdetermined problems for the Finsler p-capacity of a convex set Ω ⊂ R N , with 1 p N . In particular we show that if the Finsler p-capacitary potential u associated to Ω has two homothetic level sets then Ω is Wulff shape. Moreover, we show that the concavity exponent of u is q = − ( p − 1 ) / ( N − p ) if and only if Ω is Wulff shape.
Rectifiability and analytic capacity in the complex plane
1995
Analytic capacity and removable sets In this chapter we shall discuss a classical problem in complex analysis and its relations to the rectifiability of sets in the complex plane C . The problem is the following: which compact sets E ⊃ C are removable for bounded analytic functions in the following sense? (19.1) If U is an open set in C containing E and f : U\E → C is a bounded analytic function, then f has an analytic extension to U . This problem has been studied for almost a century, but a geometric characterization of such removable sets is still lacking. We shall prove some partial results and discuss some other results and conjectures. For many different function classes a complete so…
Heisenberg quasiregular ellipticity
2016
Following the Euclidean results of Varopoulos and Pankka--Rajala, we provide a necessary topological condition for a sub-Riemannian 3-manifold $M$ to admit a nonconstant quasiregular mapping from the sub-Riemannian Heisenberg group $\mathbb{H}$. As an application, we show that a link complement $S^3\backslash L$ has a sub-Riemannian metric admitting such a mapping only if $L$ is empty, the unknot or Hopf link. In the converse direction, if $L$ is empty, a specific unknot or Hopf link, we construct a quasiregular mapping from $\mathbb{H}$ to $S^3\backslash L$. The main result is obtained by translating a growth condition on $\pi_1(M)$ into the existence of a supersolution to the $4$-harmonic…
Lipschitz classes and the Hardy-Littlewood property
1993
We study the geometry of plane domains and the uniform Holder continuity properties of analytic functions.
The annular decay property and capacity estimates for thin annuli
2016
We obtain upper and lower bounds for the nonlinear variational capacity of thin annuli in weighted $\mathbf{R}^n$ and in metric spaces, primarily under the assumptions of an annular decay property and a Poincar\'e inequality. In particular, if the measure has the $1$-annular decay property at $x_0$ and the metric space supports a pointwise $1$-Poincar\'e inequality at $x_0$, then the upper and lower bounds are comparable and we get a two-sided estimate for thin annuli centred at $x_0$, which generalizes the known estimate for the usual variational capacity in unweighted $\mathbf{R}^n$. Most of our estimates are sharp, which we show by supplying several key counterexamples. We also character…
Innovation through implementation of a quality improvement method : A finnish public-sector case
2019
Purpose The purpose of this paper is to analyse the effectiveness of a quality improvement method in driving innovation in the public sector. The study expands on the concept of innovation and analyses the types and usefulness of the innovations observed. Design/methodology/approach The study utilizes an action research approach. The aim of the quality improvement method introduced is to generate innovations enhancing efficiency. An interventionist research method is required to produce the findings. Data collection methods include a preliminary question sheet, interview, workshops, observation and the examination of other material concerning the case organization. Findings The study suppo…
Timed up-and-go performance is associated with objectively measured life space in patients 3 months after ischemic stroke: a cross-sectional observat…
2023
Background Stroke is a common cause of mobility limitation, including a reduction in life space. Life space is defined as the spatial extent in which a person moves within a specified period of time. We aimed to analyze patients' objective and self-reported life space and clinical stroke characteristics. Methods MOBITEC-Stroke is a prospective observational cohort study addressing poststroke mobility. This cross-sectional analysis refers to 3-month data. Life space was assessed by a portable tracking device (7 consecutive days) and by self-report (Life-Space Assessment; LSA). We analysed the timed up-and-go (TUG) test, stroke severity (National Institutes of Health Stroke Scale; NIHSS), and…