Search results for "Cardiac"

Adaptive Methodology for Designing a Predictive Model of Cardiac Arrhythmia Symptoms Based on Cubic Neural Unit

2017

A cubic neural unit is a kind of a higher-order neural unit which can be used for prediction tasks among others, in the medical field. The example of the tasks includes monitoring cardiac behavior in real-time either for preemptive treatment, or for supporting a doctor to reach a more accurate diagnosis. We propose a predictive model which has been developed as an application in open source code with the aim to make it publicly accessible for research community and medical professionals and also to decrease the implementation cost. The proposed model uses sample-by-sample adaptation of the gradient descent method with error backpropagation. This paper presents an application of a cubic neur…

Micro – Meso scale based biomechanical models to assist the design and fabrication of scaffolds for Cardiac Tissue Regeneration

2011

Questo lavoro presenta una strategia di modellazione strutturale basata su dati di micro-architettura finalizzata a: (A) guidare fabbricazione e progetto di scaffold per ingegneria di tessuto, (B) studiare la risposta cellulare meccanica alle deformazioni strutturali. Applicazioni cliniche ideali per la metodologia proposta sono le valvole cardiache e il patch di miocardio. Custom software di analisi d’immagine e’ stato utilizzato per caratterizzare la morfologia dei campioni. Le topologie dei materiali individuate sono state impiegate per generare equivalenti modelli a rete. Il comportamento meccanico alla macro scala e’ stato studiato mediante prove di carico biassiale. Questa messe speri…

Programa de Rehabilitación Cardiaca coordinado por Enfermería: resultados de Euroaction en España

2015

Las enfermedades cardiovasculares (ECV) siguen siendo la causa principal de muerte entre los europeos y en todo el mundo. Los factores que contribuyen a la carga de las enfermedades cardiovasculares y las enfermedades crónicas relacionadas tiene que ver con el estilo de vida, y es fundamental entender que este concepto generalmente se basa en los patrones de comportamiento a lo largo de la vida. Los programas de RHBC son una herramienta preventiva, que han demostrado revertir las prácticas poco saludables, reemplazar los factores de riesgo por comportamientos sanos y se han implementado con éxito en una variedad de entornos, en pacientes con enfermedad coronaria y en la población general, t…

Valor pronóstico de los parámetros de deformación miocárdica en una cohorte de pacientes con insuficiencia cardíaca crónica estable

2023

La insuficiencia cardiaca (IC) es una patología de gran impacto a nivel mundial por sus elevadas cifras de morbilidad-mortalidad. A pesar de que la ecocardiografía es la prueba de elección para su diagnóstico y estratificación de riesgo, presenta importantes limitaciones y es incapaz de predecir el riesgo en pacientes con FEVI preservada. El estudio de la deformación miocárdica mediante rastreo de patrones, permite estimar el porcentaje de elongación o acortamiento de cada segmento miocárdico durante el ciclo cardíaco. Ha demostrado ser un parámetro capaz de identificar la disfunción miocárdica subclínica, asociándose con el riesgo de mortalidad y episodios adversos en subgrupos seleccionad…

Psicosomatica e ischemia cardiaca:correlazio ne tra eventi stressanti,meccanismi di dife sa,personalità e stili di vita.

2009

Work engagement : psychometrical, psychosocial, and psychophysiological approach

2013

Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity

2011

Normal tissue damage limits the efficacy of anticancer therapy. For anthracyclines, the clinically most relevant adverse effect is cardiotoxicity. The mechanisms involved are poorly understood and putative cardioprotectants are controversially discussed. Here, we show that the lipid-lowering drug lovastatin protects rat H9c2 cardiomyoblasts from doxorubicin in vitro. Protection by lovastatin is related to inhibition of the Ras-homologous GTPase Rac1. It rests on a reduced formation of DNA double-strand breaks, resulting from the inhibition of topoisomerase II by doxorubicin. Doxorubicin transport and reactive oxygen species are not involved. Protection by lovastatin was confirmed in vivo. I…

Heart Rate Variability Monitoring During Strength and High-Intensity Interval Training Overload Microcycles

2019

Objective: In two independent study arms, we determine the effects of strength training (ST) and high-intensity interval training (HIIT) overload on cardiac autonomic modulation by measuring heart rate (HR) and vagal heart rate variability (HRV).Methods: In the study, 37 well-trained athletes (ST: 7 female, 12 male; HIIT: 9 female, 9 male) were subjected to orthostatic tests (HR and HRV recordings) each day during a 4-day baseline period, a 6-day overload microcycle, and a 4-day recovery period. Discipline-specific performance was assessed before and 1 and 4 days after training.Results: Following ST overload, supine HR, and vagal HRV (Ln RMSSD) were clearly increased and decreased (small ef…

Red Blood Cells Distribution Width as Biomarker of Worsening in Atherosclerosis

2018

Red blood cell Distribution Width (RDW) is a parameter of the circulating erythrocytes’ size that it has reported to be associated with Cardiovascular Diseases (CVDs) [1-7]. The related mechanism of this association is not fully understood. However, RDW is an indicator of inflammation related to early inflammatory biomarkers, such as C-reactive protein (CRP), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) [8,9]. Accordingly, systemic chronic inflammation leads to dysfunctional bone marrow with unsuccessful production of red blood cells [10]. As a result, it determines the migration of reticulocytes into the peripheral circulation, followed by an increase in circulating levels of i…

RED BLOOD CELL DISTRIBUTION WIDTH PREDICTS MORBIDITY AND MORTALITY AFTER AORTIC VALVE REPLACEMENT

2014

Objective: Red blood cell distribution width (RDW), is a measurement of the size variation as well as an erythrocyte heterogeneity index (i.e., anysocytosis). used in combination with the mean corpuscular volume for anemia diagnosis. However, it is emerging as an useful predictor biomarker of mortality and morbidity of cardiovascular diseases. However, until now no literature data there are about the RDW role in predicting mortality after aortic valve replacement (AVR). Thus, in this pilot study biological significance of elevated RDW values in early outcome following AVR was evaluated Methods: We enrolled 75 patients (mean age 73.5 ±7.9 years) subjected to AVR and/ or not co temporally to …