Search results for "Castanospermine"

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Polyhydroxylated indolizidine alkaloids-synthesis of dideoxycastanospermine

2009

The key transformation developed in this work is the anti-Kishi selective dihydroxylation, which proceeds by way of intramolecular participation of the nitrogen protecting group to furnish the desired stereochemistry required for castanospermine like structures. In this paper, we completed a first syn-thesis of a novel dideoxycastanospermine 6. Peer reviewed

Intramolecular reactionStereochemistryOrganic ChemistryIndolizidineBiochemistryChemical synthesischemistry.chemical_compoundCastanosperminechemistryDihydroxylationIntramolecular forceDrug DiscoveryChemical reductionOrganic chemistryProtecting group
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