Search results for "Cells"

showing 10 items of 7920 documents

Calcium homeostasis in plant cell nuclei

2009

International audience; In plant cells, calcium-based signaling pathways are involved in a large array of biological processes, including cell division, polarity, growth, development and adaptation to changing biotic and abiotic environmental conditions. Free calcium changes are known to proceed in a nonstereotypical manner and produce a specific signature, which mirrors the nature, strength and frequency of a stimulus. The temporal aspects of calcium signatures are well documented, but their vectorial aspects also have a profound influence on biological output. Here, we will focus on the regulation of calcium homeostasis in the nucleus. We will discuss data and present hypotheses suggestin…

0106 biological sciencesCELL NUCLEUSHOMEOSTASISAUTONOMYCell divisionPhysiologyAequorinchemistry.chemical_elementPlant ScienceCalcium01 natural sciencesCALCIUM03 medical and health sciencesCytosolPlant CellsOrganellemedicineCalcium SignalingCELLULE VEGETALE030304 developmental biologyCalcium metabolism0303 health sciencesbiologyAEQUORINEAEQUORINCell biology[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacymedicine.anatomical_structurechemistryHOMEOSTASIEbiology.proteinSignal transductionNucleusHomeostasis010606 plant biology & botanySignal Transduction
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Selection for Robustness in Mutagenized RNA Viruses

2007

Mutational robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Whether robustness can be directly favored by natural selection remains controversial. Theory and in silico experiments predict that, at high mutation rates, slow-replicating genotypes can potentially outcompete faster counterparts if they benefit from a higher robustness. Here, we experimentally validate this hypothesis, dubbed the ‘‘survival of the flattest,’’ using two populations of the vesicular stomatitis RNA virus. Characterization of fitness distributions and genetic variability indicated that one population showed a higher replication rate, whereas the other was more robust to mut…

0106 biological sciencesCancer ResearchMutation ratelcsh:QH426-470In silicoMolecular Sequence DataPopulationBiologyVirus Replication010603 evolutionary biology01 natural sciencesVesicular stomatitis Indiana virusCell Line03 medical and health sciences0302 clinical medicineVirologyCricetinaeGeneticsAnimalsHumansSelection GeneticeducationMolecular BiologyGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyGeneticsEvolutionary Biology0303 health scienceseducation.field_of_studyNatural selectionRobustness (evolution)Genetics and GenomicsRNA virusbiology.organism_classification3. Good healthlcsh:GeneticsViral replicationMutagenesisViral evolutionViruses030217 neurology & neurosurgeryResearch ArticleHeLa Cells
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The Spodoptera exigua ABCC2 Acts as a Cry1A Receptor Independently of its Nucleotide Binding Domain II

2019

ABC proteins are primary-active transporters that require the binding and hydrolysis of ATP to transport substrates across the membrane. Since the first report of an ABCC2 transporter as receptor of Cry1A toxins, the number of ABC transporters known to be involved in the mode of action of Cry toxins has increased. In Spodoptera exigua, a mutation in the SeABCC2 gene is described as genetically linked to resistance to the Bt-product XentariTM. This mutation affects an intracellular domain involved in ATP binding, but not the extracellular loops. We analyzed whether this mutation affects the role of the SeABCC2 as a functional receptor to Cry1A toxins. The results show that Sf21 cells express…

0106 biological sciencesCell SurvivalHealth Toxicology and Mutagenesislcsh:MedicineReceptors Cell SurfaceATP-binding cassette transporterSpodopteraSpodopteraToxicologymedicine.disease_causeBt resistance01 natural sciencesArticleCell LineHemolysin Proteins03 medical and health sciencesBacterial Proteinsmode of actionGTP-Binding ProteinsATP hydrolysismedicineAnimalsReceptor030304 developmental biology0303 health sciencesMutationBacillus thuringiensis ToxinsbiologyChemistryfungilcsh:Rheterologous expressionTransporterbiology.organism_classificationMultidrug Resistance-Associated Protein 2Cell biologyEndotoxins010602 entomologyCyclic nucleotide-binding domainSf21 cellstruncated transporterInsect ProteinsHeterologous expressionMultidrug Resistance-Associated ProteinsToxins
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Subcellular localization and purification of a p-hydroxyphenylpyruvate dioxygenase from cultured carrot cells and characterization of the correspondi…

1997

p-Hydroxyphenylpyruvate dioxygenase catalyses the transformation of p-hydroxyphenylpyruvate into homogentisate. In plants this enzyme has a crucial role because homogentisate is the aromatic precursor of all prenylquinones. Furthermore this enzyme was recently identified as the molecular target for new families of potent herbicides. In this study we examine precisely the localization of p-hydroxyphenylpyruvate dioxygenase activity within carrot cells. Our results provide evidence that, in cultured carrot cells, p-hydroxyphenylpyruvate dioxygenase is associated with the cytosol. Purification and SDS/PAGE analysis of this enzyme revealed that its activity is associated with a polypeptide of 4…

0106 biological sciencesDNA ComplementaryMolecular Sequence DataBiology4-Hydroxyphenylpyruvate Dioxygenase01 natural sciencesBiochemistry03 medical and health sciencesDioxygenaseComplementary DNA[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyAmino Acid SequenceCloning MolecularMolecular BiologyPeptide sequenceCells CulturedComputingMilieux_MISCELLANEOUS030304 developmental biologyHomogentisate 12-dioxygenase0303 health sciencesBase SequenceSequence Homology Amino AcidMolecular massDioxygenase activityNucleic acid sequenceCell BiologyMolecular biologyDaucus carotaBiochemistryElectrophoresis Polyacrylamide Gel4-Hydroxyphenylpyruvate dioxygenaseResearch ArticleChromatography LiquidSubcellular Fractions010606 plant biology & botany
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Phytochemical profiles, phototoxic and antioxidant properties of eleven Hypericum species - A comparative study

2018

Hypericum is one out of the nine genera belonging to the botanical family Clusiaceae Lindl (syn. Hypericaceae Juss.; APG III, 2009). The genus contains 484 species spread worldwide, one of which, Hypericum perforatum, is largely used in folk medicine. The aim of this study was to evaluate the chemical composition, along with the antioxidant and phototoxic activity, of 11 Hypericum species grown in Sicily (H. perforatum L., H. aegypticum L., H. androsaemum L., H. calycinum L., H. hircinum L., H. hirsutum L., H. montanum L., H. patulum Thunb., H. perfoliatum L., H. pubescens Boiss., H. tetrapterum Fr.). Samples of flowering tops collected from these Hypericum species were extracted and analys…

0106 biological sciencesDPPHHyperforinAntioxidants Hyperforin Hypericin Hypericum species (Clusiaceae Lindl.) Phototoxicity; PolyphenolsPhytochemicalsHypericinFlowersPlant ScienceHorticultureHypericaceae01 natural sciencesBiochemistryAntioxidantsMass SpectrometryPhototoxicityMicechemistry.chemical_compoundPicratesSpecies SpecificityHypericum species (Clusiaceae Lindl.) Phototoxicity Polyphenols Hypericin Hyperforin AntioxidantsAnimalsHypericum species (Clusiaceae Lindl.)Molecular BiologyChromatography High Pressure LiquidbiologyTraditional medicine010405 organic chemistryChemistryBiphenyl CompoundsPolyphenolsHypericum perforatumGeneral MedicineFibroblastsbiology.organism_classificationSettore AGR/02 - Agronomia E Coltivazioni Erbacee0104 chemical sciencesHypericinHyperforinPhotochemotherapyPhytochemicalPolyphenolNIH 3T3 CellsAntioxidantReactive Oxygen SpeciesHypericumHypericumDermatitis Phototoxic010606 plant biology & botany
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Fatty acid hydroperoxide lyase of green bell pepper: cloning in Yarrowia lipolytica and biogenesis of volatile aldehydes

2004

Publication Inra prise en compte dans l'analyse bibliométrique des publications scientifiques mondiales sur les Fruits, les Légumes et la Pomme de terre. Période 2000-2012. http://prodinra.inra.fr/record/256699; International audience; Fatty acid hydroperoxide lyase (HPO lyase) is a cytochrome P450 acting on fatty acid hydroperoxides in many organisms. The expression of green bell pepper HPO lyase in the yeast Yarrowia lipolytica is described for the first time. HPO lyase activity from yeast extract and whole yeast cells is measured and aldehydes production from yeast extract and whole yeast cells is compared. 1200 U/L reaction medium were obtained after 96 h of culture on olive oil rich me…

0106 biological sciencesEXPRESSIONBioconversionVOLATILE COMPOUNDSBioengineeringBiology01 natural sciencesApplied Microbiology and BiotechnologyBiochemistryCLONING03 medical and health sciencesSUBSTRATEBiotransformation010608 biotechnologyYeast extractLyase activity030304 developmental biologychemistry.chemical_classificationHYDROPHOBICITY0303 health sciencesBIOCONVERSIONfungiYarrowiabiology.organism_classificationLyaseYeastYARROWIA LIPOLYTICAHYDROPEROXIDE LYASEEnzyme[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologychemistryBiochemistryWHOLE CELLSFATTY ACIDBiotechnology
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The roles of temperature, nest predators and information parasites for geographical variation in egg covering behaviour of tits (Paridae)

2020

Abstract Aim: Nest building is widespread among animals. Nests may provide receptacles for eggs, developing offspring and the parents, and protect them from adverse environmental conditions. Nests may also indicate the quality of the territory and its owner and can be considered as an extended phenotype of its builder(s). Nests may, thus, function as a sexual and social signal. Here, we examined ecological and abiotic factors—temperature, nest predation and interspecific information utilization—shaping geographical variation in a specific nest structure—hair and feather cover of eggs—and its function as an extended phenotype before incubation in great (Parus major) and blue tits (Cyanistes …

0106 biological sciencesEconomicsBiology010603 evolutionary biology01 natural sciencesPredation03 medical and health sciencesCyanistes caeruleusNestbird nestParus majorBiologyEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS030304 developmental biology0303 health sciencesbreeding successEcologyOcellsEcologyextended phenotype15. Life on landBird nestChemistryVariation (linguistics)[SDE]Environmental Sciencesnest structure
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Colonization of flax roots and early physiological responses of flax cells inoculated with pathogenic and nonpathogenic strains of Fusarium oxysporum

2003

ABSTRACT Fusarium oxysporum includes nonpathogenic strains and pathogenic strains that can induce necrosis or tracheomycosis in plants. The objective of this study was to compare the abilities of a pathogenic strain (Foln3) and a nonpathogenic strain (Fo47) to colonize flax roots and to induce early physiological responses in flax cell culture suspensions. Both strains colonized the outer cortex of the root; however, plant defense reactions, i.e., the presence of wall appositions, osmiophilic material, and collapsed cells, were less frequent and less intense in a root colonized by Foln3 than by Fo47. Early physiological responses were measured in flax cell suspensions confronted with germin…

0106 biological sciencesFusariumCell Culture TechniquesFungus01 natural sciencesApplied Microbiology and BiotechnologyPlant RootsMicrobiologyConidium03 medical and health sciencesPlant MicrobiologyFusariumFlaxFusarium oxysporumExtracellularCells CulturedComputingMilieux_MISCELLANEOUS030304 developmental biologyPlant Diseases[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciencesEcologybiologyInoculationfood and beveragesFungi imperfectiHydrogen PeroxideHydrogen-Ion Concentrationbiology.organism_classificationKinetics[SDV.EE] Life Sciences [q-bio]/Ecology environmentCell cultureREPONSE DE LA PLANTECalcium010606 plant biology & botanyFood ScienceBiotechnology
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The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation

2007

The smallest known eukaryotes, at ≈1-μm diameter, are Ostreococcus tauri and related species of marine phytoplankton. The genome of Ostreococcus lucimarinus has been completed and compared with that of O. tauri . This comparison reveals surprising differences across orthologous chromosomes in the two species from highly syntenic chromosomes in most cases to chromosomes with almost no similarity. Species divergence in these phytoplankton is occurring through multiple mechanisms acting differently on different chromosomes and likely including acquisition of new genes through horizontal gene transfer. We speculate that this latter process may be involved in altering the cell-surface character…

0106 biological sciencesGenome evolutionProtein familyGene Transfer Horizontal[SDV]Life Sciences [q-bio]Molecular Sequence DataBiologyEnvironment01 natural sciencesGenomeChromosomesOstreococcus tauriOstreococcus03 medical and health sciencesChlorophyta[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]SelenoproteinsGeneComputingMilieux_MISCELLANEOUS030304 developmental biologyGeneticsCell Nucleus0303 health sciencesMultidisciplinaryMetal metabolismGenomeVitaminsBiological Sciencesbiology.organism_classificationPlanktonAdaptation PhysiologicalBiological EvolutionEukaryotic CellsMetalsHorizontal gene transfer010606 plant biology & botany
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Tobacco cells contain a protein, immunologically related to the neutrophil small G protein Rac2 and involved in elicitor-induced oxidative burst.

1997

Abstract Suspension-cultured cells of Nicotiana tabacum generated active oxygen species (AOS) when they were treated with the proteinaceous elicitor, cryptogein. This response was blocked by diphenylene iodonium, an inhibitor of the neutrophil NADPH oxidase. When microsomal extracts of tobacco cells were probed with an antibody directed against the human small G protein Rac2, two immunoreactive proteins were detected at 18.5 and 20.5 kDa. The same experiment performed with cytosolic extracts of tobacco cells led to the observation of a strong immunoreactive protein at 21.5 kDa only in the cryptogein-treated cells. The appearance of this cytosolic protein was related to the production of AOS…

0106 biological sciencesHypersensitive responseNicotiana tabacumBlotting WesternBiophysicsSmall G Protein01 natural sciencesBiochemistrySuperoxide dismutaseFungal Proteins03 medical and health sciencesStructural BiologyGTP-Binding ProteinsTobaccoGeneticsMolecular BiologyCells Cultured030304 developmental biologyRespiratory Burst0303 health sciencesNADPH oxidasebiologyNADPH oxidaseNicotiana tabacumAlgal Proteinsfood and beveragesCell Biologybiology.organism_classificationMolecular biologyOxidative burst3. Good healthElicitorRespiratory burstrac GTP-Binding ProteinsSmall G proteinCytosolPlants ToxicBiochemistrybiology.proteinCryptogeinReactive Oxygen Species010606 plant biology & botanyRac2FEBS letters
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