Search results for "Centaur"

showing 10 items of 105 documents

Acid rearrangment of epoxy-germacranolides and absolute configuration of 1beta, 10alpha-epoxy-salonitenolide

2010

The acid-catalyzed cyclization of mono epoxides of cnicin acetonide (3) was investigated. Several 6,12-eudesmanolides were obtained, and their stereochemistry established by extensive spectroscopic analyses. Chemical correlations also led to the assignment of the absolute configuration of 1beta,10alpha-epoxy-salonitenolide (13), a previously isolated natural product. The cytotoxic activities of some compounds were determined against A549 and MCF-7 tumor cell lines. The esterified germacranolides 2-6 were selectively cytotoxic against the MCF-7 breast cancer cell line.

Magnetic Resonance SpectroscopyMolecular StructurePlant ExtractsCentaureaSettore CHIM/06 - Chimica Organicagermacranolides epoxygermacranolides cyclization eudesmanolides absolute configuration cytotoxicityAntineoplastic Agents PhytogenicSesquiterpenes GermacraneCell Line TumorHumansDrug Screening Assays AntitumorSesquiterpenesSicilyCell Proliferation
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The wild taxa utilized as vegetables in Sicily (Italy): a traditional component of the Mediterranean diet

2018

Background: Wild vegetables in the Mediterranean Basin are still often consumed as a part of the diet and, in particular, there is a great tradition regarding their use in Sicily.In this study, an ethnobotanical field investigation was carried out to (a) identify the wild native taxa traditionally gathered and consumed as vegetables in Sicily, comparing the collected ethnobotanical data with those of other countries that have nominated the Mediterranean diet for inclusion in the UNESCO Representative List of the Intangible Cultural Heritage of Humanity and (b) highlight new culinary uses of these plants.Methods: Interviews were carried out in 187 towns and villages in Sicily between 2005 an…

Male0106 biological sciencesHealth (social science)Mediterranean dietEthnobotanyRural cultural heritageDiet Mediterranean01 natural sciencesMediterranean BasinSettore BIO/01 - Botanica Generalelcsh:BotanyVegetablesSicilyAged 80 and over2. Zero hungerbiologySettore BIO/02 - Botanica SistematicaNasturtium officinaleCultural Studielcsh:Other systems of medicineMiddle AgedComplementary and Alternative Medicine2708 DermatologyBiocultural diversitylcsh:QK1-989Centaurea calcitrapaGeographyTraditional knowledgeEthnobotanyCarduuslanguageFemalePlants EdibleGeneral Agricultural and Biological SciencesSicilianCultural StudiesTraditional agroecosystemfoodBotanyHumansTraditional agroecosystemsAgedBiocultural diversity; Ethnobotany; Rural cultural heritage; Traditional agroecosystems; Traditional knowledge; Health (social science); Cultural Studies; Agricultural and Biological Sciences (all); Complementary and Alternative Medicine2708 DermatologyResearch15. Life on landlcsh:RZ201-999biology.organism_classificationfood.foodlanguage.human_language0104 chemical sciences010404 medicinal & biomolecular chemistryAgricultural and Biological Sciences (all)Complementary and alternative medicineSettore BIO/03 - Botanica Ambientale E Applicata010606 plant biology & botanyOnopordum illyricumJournal of Ethnobiology and Ethnomedicine
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Head-to-head comparison of plasma cTnI concentration values measured with three high-sensitivity methods in a large Italian population of healthy vol…

2019

Abstract Background The study aim is to compare cTnI values measured with three high-sensitivity (hs) methods in apparently healthy volunteers and patients admitted to emergency department (ED) with acute coronary syndrome enrolled in a large multicentre study. Methods Heparinized plasma samples were collected from 1511 apparently healthy subjects from 8 Italian clinical institutions (mean age: 51.5 years, SD: 14.1 years, range: 18–65 years, F/M ratio:0.95). All volunteers denied chronic or acute diseases and had normal values of routine laboratory tests. Moreover, 1322 heparinized plasma sample were also collected by 9 Italian clinical institutions from patients admitted to ED with clinica…

Male0301 basic medicineprincipal component analysisvery elderlyClinical BiochemistryheparinizationBiochemistryPatient Admission0302 clinical medicineReference ValuesLimit of Detectionblood analysisTroponin IHealthy volunteers80 and overMyocardial infarctionAcute coronary syndrome; Cardiac troponins; High-sensitivity methods; Myocardial infarction; Reference population values; Acute Coronary Syndrome; Adolescent; Adult; Aged; Aged 80 and over; Blood Chemical Analysis; Female; Humans; Italy; Male; Middle Aged; Myocardium; Patient Admission; Reference Values; Troponin I; Young Adult; Emergency Service Hospital; Healthy Volunteers; Limit of DetectionReference population valuescomparative studyHigh-sensitivity methodsAged 80 and overemergency wardEmergency Servicehospital emergency servicetroponin I acute coronary syndromeSettore BIO/12clinical trialGeneral Medicinecardiac troponin 1 CLIAMiddle AgedHealthy Volunteerspriority journalItaly030220 oncology & carcinogenesisCardiac troponinFemaleAcute coronary syndromeEmergency Service HospitalAdultmedicine.medical_specialtyAcute coronary syndromecardiac muscleAdolescentHead to headheart infarctionArticleYoung AdultHospital03 medical and health sciencesbloodInternal medicinemedicinesexHumanscontrolled studyADVIA Centaurdiagnostic test accuracy studyhumannormal humanproceduresAgedbusiness.industryMyocardiumTroponin IBiochemistry (medical)reference valueEmergency departmentmedicine.diseasemajor clinical studyhospital admissionyoung adult Acute Coronary SyndromeHigh-sensitivity methodMyocardial infarctionmulticenter study030104 developmental biologySettore BIO/12 - Biochimica Clinica E Biologia Molecolare Clinicaageprotein blood levelReference valuesCardiac troponinsbusinessmetabolismBlood Chemical Analysis
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Typification of the Linnaean name Centaurea seridis (Asteraceae)

2014

The genus Centaurea Linnaeus (1753: 909) (Asteraceae) comprises a large number of taxa mainly occurring in the Mediterranean region and southwest Asia (Susanna & Garcia-Jacas 2007). Centaurea seridis Linnaeus (1753: 915) is distributed from south Europe (Spain incl. Balearic Islands, Italy incl. Sicily, France, Albania and Greece) to northwest Africa (Algeria, Morocco and Tunisia). From a nomenclatural standpoint, Centaurea seridis has not been typified (Jarvis 2007: 402). This paper proposes the designation of a lectotype for this Linnaean name, based on the analysis of the protologue and original material.

Mediterranean climateBalearic islandsbiologyAsteralesgovernment.political_districtPlant ScienceBiodiversityAsteraceaeAsteraceaebiology.organism_classificationTracheophytaMagnoliopsidaTaxonCentaureaGenusBotanygovernmentTypificationPlantaeEcology Evolution Behavior and SystematicsTaxonomy
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Guaianolides and lignans from the aerial parts of Centaurea ptosimopappa.

2006

The genus Centaurea L. (Asteraceae, tribe Cardueae, subtribe Centaureinae) comprises ca. 600 species distributed in Asia, Europa, North Africa and America (Hickey and King, 1981; Heywood, 1979). Turkish flora numbers 187 species, 114 of which being endemic (Davis, 1975; Davis et al., 1988; Wagenitz et al., 1988; Guner et al., 2000; Duran and Duman, 2000; Turkoglu et al., 2003). Centaurea ptosimopappa Hayek is an endemic species distributed in the Mediterranean and South-Eastern Anatolian regions of Turkey; widespread and locally frequent in the Amanos and Casus mountains (Davis, 1975; Reeves and Adiguzel, 2004). Aerial parts of C. ptosimopappa were collected in Hatay, the Amanos Mountain ab…

Mediterranean climatebiologyGenusCentaureaBotanyCentaureinaeAsteraceaebiology.organism_classificationTribe (biology)Centaurea ptosimopappaEndemismBiochemistryEcology Evolution Behavior and Systematics
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2021

The genus Centaurea is recognized in folk medicine for anti-inflammatory, anti-itch, antitussive, purgative, astringent, and tonic activities. To study the chemical determinant for antimicrobial activity essential oils (EOs), five Centaurea species were analyzed including: C. scoparia, C. calcitrapa, C. glomerata, C. lipii and C. alexandrina. Conventional hydro-distillation (HD) and microwave-assisted extraction (MAE), as new green technologies, were compared for the extraction of essential oils. GC/MS analysis identified 120 EOs including mostly terpenoid except from C. lipii and C. alexandrina in which nonterpenoids were the major constituents. Major terpenoids included spathulenol, caryo…

Microbiology (medical)biologyTraditional medicine010405 organic chemistryChemistryAspergillus nigerAsteraceaebiology.organism_classificationAntimicrobial01 natural sciencesBiochemistryMicrobiologyDNA gyraseTerpenoid0104 chemical sciences010404 medicinal & biomolecular chemistryInfectious DiseasesCentaureaPharmacology (medical)General Pharmacology Toxicology and PharmaceuticsScopariaAntibacterial activityAntibiotics
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The vascular flora of Nature Reserve “Pizzo Cane, Pizzo Trigna and Grotta Mazzamuto” (NW Sicily)

2009

A floristic investigation was carried out in “Pizzo Cane, Pizzo Trigna and Grotta Mazzamuto” Nature Reserve, one of the largest in Sicily. In spite of the considerable botanical interest of this area, few data were available from classic and recent literature. Based on field investigations, coupled with bibliographic and herbarium researches, we have listed 951 infrageneric taxa belonging to 103 families and 446 genera. A lot of these entities are reported in this area for the first time, for others ancient records are confirmed. Life form analysis shows the dominance of therophytes (44,79%) and hemicryptophytes (27,77%). From a chorological point of view, Mediterranean elements show a grea…

Nature reserveFloraEcologybiologyendemism floristic biodiversity phytogeography Nature reserve SicilyEcologySettore BIO/02 - Botanica SistematicaPlant SciencePhytogeographybiology.organism_classificationFloristicsHerbariumCentaureaEryngiumEndemismEcology Evolution Behavior and SystematicsWebbia
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Zvaigžņotā Debess: 2013, Vasara (220)

2013

Saturs: Pēdējā "Apollo" ekspedīcija uz Mēnesi ; Vissavienības Astronomijas un ģeodēzijas biedrības Latvijas nodaļa ; M.Gills. ESON – astronomijas popularizēšanas tīkls ; S.Kropa. Dvēsele Atakamas tuksnesī ; M.G. Īsumā: ESO Astro Camp Eiropas vidusskolēniem 2013.gada decembrī ; A.Alksnis. Atklāta vēl viena no Saulei vistuvākajām kaimiņzvaigznēm ; A.Alksnis. Tuvēja zvaigzne, kas ir izveidojusies jau drīz pēc Lielā Sprādziena ; A.Alksnis. Čeļabinskas superbolīds – simtgades notikums ; A.Alksnis. Nevis pārsteidzoša nova, bet gan kvazāra uzliesmojums ; I.Eglītis. Orius – Baldones observatorijā atklātais centaurs ; R.Misa. Denisa Tito Marsa iedvesmas fonds ; A.A. Īsumā: Ap zvaigzni Gleznotāja Bet…

Otrais seminārs „Astronomijas izglītība Latvijā”ESON – astronomijas popularizēšanas tīklsESO Astro Camp vidusskolēniemAptauja’2012 – izlozes rezultātiSenie ziemeļbriežu mednieki Latvijas teritorijāBulīšu akmens meteorītam – 150Doc. E.Grinbergs – uzruna 15.06.1978.LU Astronomijas institūts 2012.gadāmāksla-skaitļi-astronomija [Homo sapiens]Saules pulkstenis Origo Universi Rīgas Stacijas laukumāM 31 nova No 21 – kvazāra uzliesmojumsLU fizikas docents Valdis RēvaldsCentaurs Orius – atklāts Baldones observatorijāČeļabinskas superbolīdsDubultzvaigzne WISE 1049-5319Atakamas Lielais mm/submm režģis ALMA – atklāšanaXVIII Starptautiskā astronomijas olimpiāde ViļņāZvaigžņu tēma mākslā – dzeja un zīmējumi:NATURAL SCIENCES::Physics::Astronomy and astrophysics [Research Subject Categories]Pilnmēness fāzes un Mēness aptumsumu laikiZvaigznes Gleznotāja Beta planēta bDenisa Tito Marsa iedvesmas fondsAstronomam Matīsam Dīriķim – 902012.g. 14.nov. pilnais Saules aptumsums AustrālijāNoteiktības principsLatvijas 63.matemātikas olimpiāde – 3.posma uzdevumiAstronomiskās parādības – 2013.gada vasaraZentas Alksnes bērnības atmiņas – izvilkumsZvaigzne HD 140283Amatierastronomijas seminārs „Ērgļa Hī”LVU astronomijas studenti – 1952.gada diplomandiPirmatnējā zvaigzne LRLL 54361
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The essential oil composition of the endemic plant species Centaurea vandasii and chemotaxonomy of section Phalolepis (Asteraceae)

2021

In the present study, the chemical composition of the essential oil from aerial parts of the endemic plant species, Centaurea vandasii Velen (sect. Phalolepis, Asteraceae), collected in its locus classicus in Rhodope Mts, Bulgaria, was evaluated by GC-MS. The main components of the oil were hexadecanoic acid (18.3%), tetradecanoic acid (13.8%), caryophyllene oxide (12.1%) and germacrene D (8.4%). Furthermore, a complete literature review on the composition of the essential oils of all the other taxa of Centaurea, belonging to section Phalolepis, studied so far, was performed. HCA (Hierarchical Cluster Analysis) and PCA (Principal Component Analyses) were used in order to demonstrate chemota…

PCAbiologyOrganic ChemistryPlant ScienceAsteraceaeAsteraceaebiology.organism_classificationBiochemistryAnalytical Chemistrylaw.inventionchemotaxonomyTaxonCentaureaChemotaxonomylawBotanysection PhalolepisPlant speciesComposition (visual arts)GC-MSessential oilsChemical compositionEssential oilCentaurea vandasiiNatural Product Research
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Cytotoxic activity of some natural and synthetic guaianolides

2005

Several natural guaianolides and synthetic derivatives of repin (1) were tested and found to be active against tumor cell replication. Repin (1) and both mono- and di-halohydrin analogues (2, 7-9, 11, 12) showed significant antitumor potency. A more effective compound (17) was obtained by esterificating repin with the paclitaxel side chain.

PaclitaxelStereochemistryPharmaceutical ScienceEpoxideSesquiterpeneAnalytical Chemistrychemistry.chemical_compoundStructure-Activity RelationshipDrug DiscoveryTumor Cells CulturedPotencyHumansCytotoxicityPharmacologychemistry.chemical_classificationMolecular StructureChemistryOrganic ChemistrySettore CHIM/06 - Chimica OrganicaAntineoplastic Agents PhytogenicIn vitroTerpenoidCentaurea Asteraceae sesquiterpene lactonesComplementary and alternative medicinePaclitaxelMolecular MedicineDrug Screening Assays AntitumorSesquiterpenesLactone
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