Search results for "Cerebral hemorrhage"
showing 10 items of 88 documents
Temporal Trends in Sex Differences With Regard to Stroke Incidence
2016
Background and Purpose— We evaluated temporal trends in stroke incidence between men and women to determine whether changes in the distribution of vascular risk factors have influenced sex differences in stroke epidemiology. Methods— Patients with first-ever stroke including ischemic stroke, spontaneous intracerebral hemorrhage, subarachnoid hemorrhage, and undetermined stroke between 1987 and 2012 were identified through the population-based registry of Dijon, France. Incidence rates were calculated for age groups, sex, and stroke subtypes. Sex differences and temporal trends (according to 5-year time periods) were evaluated by calculating incidence rate ratios (IRRs) with Poisson regress…
Increasing Burden of Stroke: The Dijon Stroke Registry (1987–2012)
2017
<b><i>Background:</i></b> We aimed to provide a representation of the global burden of stroke. <b><i>Methods:</i></b> All cases of stroke were prospectively identified through the population-based registry of Dijon, France (1987–2012). Attack rates and mortality rates (defined as stroke leading to death within 30 days) were standardized to the European standard. Sex differences and temporal trends were evaluated by calculating rate ratios (RRs). <b><i>Results:</i></b> In all, 5,285 stroke cases (52.7% women) were recorded. The standardized attack rate was 98.2/100,000/year and the mortality rate was 12/100,000/year, and…
Determinants of Case Fatality After Hospitalization for Stroke in France 2010 to 2015.
2019
Background and Purpose— The aims of this study were to (1) describe early and late case fatality rates after stroke in France, (2) evaluate whether their determinants differed, and (3) analyze time trends between 2010 and 2015. Methods— Data were extracted from the Système National des données de santé database. Patients hospitalized for stroke each year from 2010 to 2015, aged ≥18 years, and affiliated to the general insurance scheme were selected. Cox regressions were used to separately analyze determinants of 30-day and 31- to 365-day case fatality rates for each stroke type (ischemic, intracerebral hemorrhage, and subarachnoid hemorrhage). Results— In 2015, of the 73 124 persons hospit…
Acute symptomatic seizures in cerebral venous thrombosis
2020
© 2020 American Academy of Neurology
The Influence of Oxidative Stress on Neurological Outcomes in Spontaneous Intracerebral Hemorrhage
2021
Spontaneous intracerebral hemorrhage (ICH) causes, besides the primary brain injury, a secondary brain injury (SBI), which is induced, amongst other things, by oxidative stress (OS) and inflammation, determining the patient’s outcome. This study aims to assess the impact of OS in plasma and cerebrospinal fluid (CSF) on clinical outcomes in patients with ICH. A total of 19 ICH (volume >
Frequency and determinants for hemorrhagic transformation of posterior cerebral stroke
2017
Abstract Background hemorrhagic transformation is a threatening ischemic stroke complication. Frequency of hemorrhagic transformation differs greatly among studies, and its risk factors have been usually studied in patients with anterior ischemic stroke who received thrombolytic therapy. We evaluated, in a hospital-based series of patients with posterior ischemic stroke not treated with thrombolysis, frequency and risk factors of hemorrhagic transformation. Patients with posterior circulation stroke were seen in our Department during the period January 2004 to December 2009. Demographic and clinical information were collected. We estimated risk for spontaneous hemorrhagic transformation by …
Neuroprotective effect of erythropoietin and darbepoetin alfa after experimental intracerebral hemorrhage.
2009
OBJECTIVE: Intracerebral hemorrhage (ICH) is a devastating clinical syndrome for which no truly efficacious therapy has yet been identified. In preclinical studies, erythropoietin (EPO) and its long-lasting analog, darbepoetin alfa, have been demonstrated to be neuroprotective in several models of neuronal insult. The objectives of this study were to analyze whether the systemic administration of recombinant human EPO (rHuEPO) and its long-lasting derivative darbepoetin alfa expedited functional recovery and brain damage in a rat model of ICH. METHODS: Experimental ICH was induced in rats by injecting autologous blood into the right striatum under stereotactic guidance. Subsequently, animal…
Intraparenchymal Brain Hemorrhage: "Birdlime" Effect Usefulness.
2018
The authors previously reported the novel transposition techniquefor microvascular decompression (MVD) using a tissue glue-coated collagen sponge (TachoSil Tissue Sealing Sheet; CSLBehring KK, Tokyo, Japan) soaked withfibrin glue (Tisseel 2-Component Fibrin Sealant, Vapor-Heated; Baxter Healthcare,Glendale, California, USA), termed the“birdlime”technique
Effectiveness of progestogens to improve perinatal outcome in twin pregnancies : an individual participant data meta-analysis
2015
Background In twin pregnancies, the rates of adverse perinatal outcome and subsequent long-term morbidity are substantial, and mainly result from preterm birth (PTB). Objectives To assess the effectiveness of progestogen treatment in the prevention of neonatal morbidity or PTB in twin pregnancies using individual participant data meta-analysis (IPDMA). Search strategy We searched international scientific databases, trial registration websites, and references of identified articles. Selection criteria Randomised clinical trials (RCTs) of 17–hydroxyprogesterone caproate (17Pc) or vaginally administered natural progesterone, compared with placebo or no treatment. Data collection and analysis I…
Immunohistochemical Investigation in Experimental Intracerebral Hemorrhage (ICH) and Its Correlation with Findings in Clinical Studies
1986
Since McKissock et al. 1961 investigated the effects of surgical and conservative treatment of ICH on final outcome it is well known that systemic hypertension worsens the prognosis of this serious cerebrovascular disease. Our own studies on this problem have revealed differences in final outcome, as well as in level of consciousness after ICH, between normotensive and hypertensive patients. Whilst 30.6% of the normotensive patients died, 48.1% of the hypertensive patients had a lethal outcome.