Search results for "Ceta"

showing 10 items of 1865 documents

The Vibrio choleare haemolysin anion channel is required for cell vacuolation and death

2002

SummarySeveral strains of Vibrio cholerae secrete ahaemolytic toxin of 63kDa, termed V. cholerae cytolysin (VCC). This toxin causes extensive vacuo-lation and death of cells in culture and forms ananion-selective channel in planar lipid bilayers and incells. Here, we identify inhibitors of the VCC anionchannel and show that the formation of the anionchannel is necessary for the development of the vacuoles and for the cell death induced by this toxin. Using markers of cell organelles, we show that vacuoles derive from different intracellular com-partments and we identify the contribution of lateendosomes and of the trans -Golgi network in vacuolebiogenesis.Introduction The Gram-negative bact…

4-Acetamido-4'-isothiocyanatostilbene-22'-disulfonic AcidImmunologyLipid BilayersVirulenceGolgi ApparatusVacuoleEndosomesBiology44'-Diisothiocyanostilbene-22'-Disulfonic AcidIn Vitro Techniquesmedicine.disease_causeTransfectionMicrobiologyModels BiologicalAmmonium ChlorideIon ChannelsMicrobiologyCell LineHemolysin ProteinsBacterial ProteinsVirologyOrganelleChlorocebus aethiopsmedicineAnimalsHumansSecretionVero CellsVibrio choleraeCell DeathCytotoxinsHemolysinAnti-Bacterial AgentsVibrio choleraeVacuolesCytolysinMacrolidesIntracellular
researchProduct

CCDC 1938872: Experimental Crystal Structure Determination

2020

Related Article: S. Maryamdokht Taimoory, Kwaku Twum, Mohadeseh Dashti, Fangfang Pan, Manu Lahtinen, Kari Rissanen, Rakesh Puttreddy, John F. Trant, Ngong Kodiah Beyeh|2020|J.Org.Chem.|85|5884|doi:10.1021/acs.joc.0c00220

5111723-tetramethyl-C-ethylcalix[4]resorcinarene pyridinium trifluoroacetate methanol solvate hemihydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1484545: Experimental Crystal Structure Determination

2016

Related Article: Ugur Kaya, Suruchi Mahajan, Jan-Hendrik Schöbel, Arto Valkonen, Kari Rissanen and Dieter Enders|2016|Synthesis|48|4091|doi:10.1055/s-0035-1562473

6-(3-chlorophenyl)-1-methyl-4-oxo-3-phenyl-7-thia-23-diazaspiro[4.4]non-1-en-9-yl acetateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 705738: Experimental Crystal Structure Determination

2009

Related Article: D.Meshcheryakov, V.Bohmer, M.Bolte, V.Hubscher-Bruder, F.Arnaud-Neu|2009|Chem.-Eur.J.|15|4811|doi:10.1002/chem.200802573

97979898-Tetramethyl-3435191-tetra-t-butyl-153147637995-hexaoxa-6822243840545670728688-dodeca-azapentadecacyclo[91.3.1.14549.0596.0914.01621.02530.03237.04146.04853.05762.06469.07378.08085.08994]octanonaconta-1(96)2491113161820252729323436414345485052575961646668737577808284899193-hexatriacontaene-72339557187-hexone acetonitrile ethanol ethyl acetate solvate monohydrateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1575390: Experimental Crystal Structure Determination

2017

Related Article: V. Piccialli, A. Tuzi, R. Centore|2017|Acta Crystallogr.,Sect.E:Cryst.Commun.|73|1603|doi:10.1107/S2056989017013391

9alpha11alpha-epoxy-5alpha-cholest-7-ene-3beta56alpha-triol 36-diacetateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

Are epizoites biological indicators of a western Mediterranean striped dolphin die-off?

1994

During a die-off of Mediterranean striped dolphins Stenella coeruleoalba in 1990-91, 82 individuals stranded on the Spanish coast were examined for crustacean ectoparasites and epizoites. Six species were detected: Syncyarnus aequus, PenneUa sp., Xenobalanus globicipitis, Conchoderma virgatum, Lepas pectinata and Lepas cf. hillii. The barnacles L. pectinata and L. cf. hillii are reported here for the first time on cetaceans; they were attached to the teeth. C. virgaturn was also found on the teeth; this is an unusual attachment on cetaceans. X. globicipitis showed a higher prevalence on the dolphins studied than on those stranded in the same months before (1980 to 1990) and after (1991 to 1…

:CIENCIAS DE LA VIDA::Biología animal (Zoología) [UNESCO]Die-offCrustaceans-CetaceaEpizoitesUNESCO::CIENCIAS DE LA VIDAMediterraneanUNESCO::CIENCIAS DE LA VIDA::Biología animal (Zoología)Striped dolphin:CIENCIAS DE LA VIDA [UNESCO]Epizoites ; Crustaceans-Cetacea ; Striped dolphin ; Die-off ; Mediterranean
researchProduct

Cláusulas laborales en tratados comerciales internacionales: el caso del CETA

2017

Algunos acontecimientos recientes parecen mostrar una cierta oposición de la ciudanía de los países occidentales hacia el libre comercio. De una parte, resultó bastante controvertida la numantina oposición de la pequeña región belga de Valonia a la firma del Tratado de libre comercio entre la UE y Canadá (conocido como CETA), que a punto estuvo de hacerlo descarrilar. Por otra parte, la elección de Donald Trump como presidente de los Estados Unidos parece haber dado al traste con las escasas esperanzas de alcanzar un acuerdo similar con éste país, máxime si se tiene en cuenta que uno de los argumentos centrales de su campaña electoral fue su posición a este tipo de tratados por los, a su ju…

:CIENCIAS JURÍDICAS [UNESCO]DerechoIloCetaFree tradeCiencias jurídicasUNESCO::CIENCIAS JURÍDICASClausulas laboralesOitTratados comercialesLibre comercioTradeLabour provisionsCiencias jurídicas. Generalidades
researchProduct

Die Glucuronidbildung nach peroraler Belastung mit Acetanilid bei chronischer Hepatitis und Lebercirrhose

1966

Je 12 Patienten mit laparoskopisch und histologisch gesicherter chronischer Hepatitis und Lebercirrhose erhielten peroral 800 bzw. 1200 mg Acetanilid. Als Kontrolle dienten altersmasig entsprechende Lebergesunde. 2, 6 und 24 Std nach der Belastung wurden das freie und das an Glucuronsaure gebundene N-acetyl-p-aminophenol im Serum und im 24 Std-Urin bestimmt. Auserdem wurde versucht, freies, unverandertes Acetanilid nachzuweisen. Im Urin wurde ferner die Konzentration des total konjugierten N-acetyl-p-aminphenols gemessen. Bei Patienten mit chronischer Hepatitis und Lebercirrhose waren besonders nach 1200 mg Acetanilid eine Verminderung des Glucuronids und eine Zunahme der freien Verbindung …

ACETAMINOPHEN METABOLISMGynecologymedicine.medical_specialtybusiness.industryDrug DiscoveryMolecular MedicineMedicineGeneral MedicinebusinessGenetics (clinical)Klinische Wochenschrift
researchProduct

Considering syntrophic acetate oxidation and ionic strength improves the performance of models for food waste anaerobic digestion.

2021

Current mechanistic anaerobic digestion (AD) models cannot accurately represent the underlying processes occurring during food waste (FW) AD. This work presents an update of the Anaerobic Digestion Model no. 1 (ADM1) to provide accurate estimations of free ammonia concentrations and related inhibition thresholds, and model syntrophic acetate oxidation as acetate-consuming pathway. A modified Davies equation predicted NH3 concentrations and pH more accurately, and better estimated associated inhibitory limits. Sensitivity analysis results showed the importance of accurate disintegration kinetics and volumetric mass transfer coefficients, as well as volatile fatty acids (VFAs) and hydrogen up…

ADM1Environmental EngineeringHydrogenchemistry.chemical_elementBioengineeringAcetatesModellingAmmoniachemistry.chemical_compoundBioreactorsMass transferAnaerobic digestionAnaerobiosisWaste Management and DisposalDavies equationchemistry.chemical_classificationAmmonia inhibitionRenewable Energy Sustainability and the EnvironmentOsmolar ConcentrationSyntrophic acetate oxidationGeneral MedicineRefuse DisposalAnaerobic digestionFood wastechemistryIonic strengthFoodEnvironmental chemistryPropionateMethaneBioresource technology
researchProduct

Metformin influences drug sensitivity in pancreatic cancer cells

2018

Abstract Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, highly metastatic malignancy and accounts for 85% of pancreatic cancers. PDAC patients have poor prognosis with a five-year survival of only 5–10% after diagnosis and treatment. Pancreatic cancer has been associated with type II diabetes as the frequency of recently diagnosed diabetics that develop pancreatic cancer within a 10-year period of initial diagnosis of diabetes in increased in comparison to non-diabetic patients. Metformin is a very frequently prescribed drug used to treat type II diabetes. Metformin acts in part by stimulating AMP-kinase (AMPK) and results in the suppression of mTORC1 activity and the induction o…

AMPK0301 basic medicineCancer Researchendocrine system diseases03 medical and health sciencesPancreatic cancerGeneticsMedicineAnimalsHumansDoxorubicinDrug InteractionsRapamycinSignal transduction inhibitormTORC1Molecular BiologyCisplatinSirolimusAnimalbusiness.industryPancreatic NeoplasmCancermedicine.diseaseGemcitabineMetforminMetforminPancreatic Neoplasms030104 developmental biologyDrug InteractionDocetaxelDiabetes Mellitus Type 2SirolimusCancer researchMolecular MedicinebusinessHumanmedicine.drugCarcinoma Pancreatic DuctalSignal Transduction
researchProduct