Search results for "Ché"
showing 10 items of 1731 documents
Lithic raw materials from the Petit-Chasseur site
2011
International audience
New methods for the palaeoenvironmental investigation of arid wetlands, Dead Sea edge, Jordan
2015
International audience
The Bronze Age in France
2013
L’étude archéologique des mortiers de chaux médiévaux : vers une meilleure compréhension des gestes du maçon
2020
International audience; Ces dernières décennies, l’étude des mortiers archéologiques, en particulier médiévaux, a connu un essor considérable en lien étroit avec celui de l’archéologie du bâti. Matériaux composites, possédant à la fois une forte identité géologique et un caractère anthropique certain, les mortiers sont considérés comme étant des marqueurs chronologiques potentiels pouvant aider à la compréhension de l’évolution d’un bâtiment. Mais, au-delà des problèmes de chronologie, l’étude du mortier de chaux, qui représente près de la moitié du volume d’une maçonnerie, a permis également de progresser sur la connaissance de toute la chaîne opératoire associée. Ainsi, du four à chaux au…
Boric acid toxicity to the German cockroach, Blattella germanica: Alterations in midgut structure, and acetylcholinesterase and glutathione S-transfe…
2006
0048-3575 doi: DOI: 10.1016/j.pestbp.2005.05.002; Oral toxicity of boric acid, an inorganic insecticide, was evaluated on German cockroach, Blattella germanica L. (Dictyoptera, Blattellidae). Newly emerged adults were exposed to various concentrations of boric acid incorporated into the diet. Results showed that treated insects exhibited toxic symptoms with a dose-dependent mortality. Histological study of midgut revealed alterations in the epithelial cells and a signiWcant increase in the epithelium thickness. In a second series of experiments, the compound was investigated on the activities of acetylcholinesterase (AChE) and glutathione S-transferases (GSTs). Data showed that the compound…
The antioxidant 2,3‐dichloro,5,8‐dihydroxy,1,4‐naphthoquinone inhibits acetyl‐cholinesterase activity and amyloid β 42 aggregation: A dual target the…
2020
Alzheimer's disease is characterized by amyloid β aggregation and cholinergic neurodegeneration. In the present study, pure DDN (2,3-dichloro-5,8-dihydroxy-1,4-naphthoquinone) was examined, for the first time, for its dual potential as inhibitor of acetylcholinesterase (AChE) and Aβ42 aggregation. Such investigation was encouraged by the in vitro high antioxidant potential of DDN. Indeed, it revealed interesting antioxidant activity with IC50 values of 9.8 and 4.3 µM for ABTS and reducing power, respectively. The ability of DDN to counteract Aβ42 aggregation was evaluated by thioflavine-T assay. Strong inhibition of Aβ42 aggregation of more than 90% at 25 µM was measured. Moreover, results …
la prospection systématique d’un fond de rivière : l’exemple du Doubs
2020
La présentation des méthodes mises en œuvre et des résultats obtenus à l’occasion d’une opération de prospection subaquatique systématique menée sur la rivière Doubs, en amont de Verdun-sur-le-Doubs (Saône-et-Loire), illustre en grandeur réelle l’intérêt de la démarche adoptée, fondée sur des principes simples, dans la perspective d’un inventaire systématique du patrimoine fluvial immergé. La diversité des vestiges découverts et leur répartition sur la longue durée en soulignent la pertinence mais également, s’il en était encore besoin, la réalité du formidable potentiel archéologique que recèlent les cours d’eau. The presentation of the methods used and results obtained during a systematic…
Case report : partial uniparental disomy unmasks a novel recessive mutation in the LYST gene in a patient with a severe phenotype of Chediak-Higashi …
2021
Síndrome de Chédiak-Higashi; LYST; Disomia uniparental Síndrome de Chédiak-Higashi; LYST; Disomía uniparental Chédiak-Higashi syndrome; LYST; Uniparental disomy Chédiak-Higashi syndrome (CHS) is a rare autosomal recessive (AR) immune disorder that has usually been associated to missense, nonsense or indels mutations in the LYST gene. In this study, we describe for the first time the case of a CHS patient carrying a homozygous mutation in the LYST gene inherited as a result of a partial uniparental isodisomy (UPiD) of maternal origin. Sanger sequencing of the LYST cDNA and single nucleotide polymorphism (SNP)-arrays were performed to identify the causative mutation and to explain the molecul…
Études scientifiques et marché du travail : éléments de réflexion sur la crise des formations en sciences
2007
Student disaffection towards sciences, most evident in pure science undergraduates, is causing increasing concern for the future of scientific training in France. If access to employment deteriorates more for science graduates than for graduates in other disciplines, science graduates will have a distinct advantage in terms of earnings and employment status, when the economic situation becomes less favourable. Within sciences, graduates of pure sciences have a more difficult transition from education to employment than those from applied sciences. Yet graduates from both disciplines compete for the same job in the private sector with pure science graduates receiving lower wages. The “crisis…
Killing and Preparing Animals
2015
International audience