Search results for "Chinese"

showing 10 items of 375 documents

From traditional Chinese medicine to rational cancer therapy

2007

Many natural products and derivatives thereof belong to the standard repertoire of cancer chemotherapy. Examples are Vinca alkaloids, taxanes and camptothecins. In recent years, the potential of natural products from plants, notably from medicinal plants used in traditional Chinese medicine (TCM), has been recognized by the scientific community in the Western world. To provide an example of the most recent developments in this field, we have selected several compounds, namely artesunate, homoharringtonine, arsenic trioxide and cantharidin, that are found in natural TCM products and that have the potential for use in cancer therapy. Controlled clinical studies have shown that homoharringtoni…

Cancer chemotherapyVincaPharmacognosyCancer therapyTraditional Chinese medicinechemistry.chemical_compoundNeoplasmsmedicineAnimalsHumansMedicine Chinese TraditionalArsenic trioxideMedicinal plantsMolecular BiologyTraditional medicinebiologybusiness.industryCancermedicine.diseasebiology.organism_classificationAntineoplastic Agents PhytogenicchemistryHomoharringtonineWestern WorldMolecular MedicinebusinessTrends in Molecular Medicine
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Comparison of basal cytotoxicity of seven carbamates in CHO-K1 cells

2006

The cytotoxic effects of seven carbamate pesticides, aldicarb, aldicarb sulfone, aldicarb sulfoxide, benfuracarb, pirimicarb, propoxur and thiobencarb, were compared in Chinese hamster ovary (CHO-K1) cell line of Circetulus griseus. The endpoints evaluated were lysosomal function by neutral red assay and mitochondrial integrity by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT assay). The carbamates tested were evaluated in both serum-free medium and in serum-containing medium. Results demonstrate that CHO-K1 lysosomes appeared more susceptible to propoxur, aldicarb and its metabolites than mitochondria. Aldicarb was the most toxic carbamate pesticide tested on CHO-K1 cel…

CarbamateNeutral redAldicarbHealth Toxicology and Mutagenesismedicine.medical_treatmentChinese hamster ovary cellPropoxurBiologyPirimicarbPollutionchemistry.chemical_compoundchemistryBiochemistrymedicineEnvironmental ChemistryMTT assayCytotoxicityToxicological & Environmental Chemistry
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Induction of micronucleated and binucleate cells in Chinese hamster ovary (CHO) cells by cis-diamminedichloroplatinum (II): a morphological and morph…

1990

Abstract The mutagenicity and cytotoxicity of cis -diamminedichloroplatinum (II) (cisplatin) at doses of 5, 10 and 20 μg/ml in Chinese hamster ovary (CHO) cells have been examined. A morphological characterization of several cell types induced by cisplatin was carried out. The frequencies of both cells with micronuclei and binucleate cells as a time-dependent parameter have also been studied. Whilst the number of cells with micronuclei was found to decrease with time, the number of binucleate cells increased. The possible kinetic mechanism for the production of binucleate cells and cells with micronuclei is discussed. A morphometric analysis was also performed. The nuclear area in both trea…

Cell NucleusGeneticsCisplatinCis diamminedichloroplatinum iiCell typeMicronucleus TestsDose-Response Relationship DrugChinese hamster ovary cellNuclear areaBiologyToxicologyMolecular biologyCricetinaeMicronucleus testGeneticsmedicineAnimalsCisplatinCytotoxicityInterphaseCell DivisionCells CulturedAfter treatmentmedicine.drugMutation Research/Genetic Toxicology
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Response of Chinese Hamster V79 Multicellular Spheroids Exposed to High-Energy Carbon Ions

2004

Chinese hamster V79-379A spheroids 200 +/- 30 microm (+/- SD) in diameter were irradiated in agitated medium in different oxygen atmospheres with (1) 227 MeV/nucleon (12)C(+6) ions (plateau region) to model tissue in the entrance channel during therapy, (2) carbon ions in the extended Bragg peak modeling tissue in the target volume, or (3) X rays as a reference modality. Cell survival curves were similar for modes (1) and (3), indicating the absence of a contact effect and the presence of a pronounced oxygen effect with oxygen enhancement ratios (OERs) of 2.8 and 2.9, respectively. In contrast, the oxygen effect was substantially smaller in mode (2) with an OER of 1.4. Under normal or restr…

Cell SurvivalBiophysicsAnalytical chemistrychemistry.chemical_elementApoptosisBragg peakRadiation DosageOxygenChinese hamsterCell LineIonCricetulusCricetinaeRelative biological effectivenessAnimalsRadiology Nuclear Medicine and imagingCarbon RadioisotopesIrradiationRadiationbiologyX-RaysCell CycleSpheroidDose-Response Relationship Radiationbiology.organism_classificationOxygenchemistryAtomic physicsCarbonCell DivisionRelative Biological EffectivenessRadiation Research
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Junceosides A-C, new triterpene saponins from Arenaria juncea.

2002

Three novel triterpenoid saponins, junceosides A (1), B (2), and C (3), together with two known saponins have been isolated from the roots of Arenaria juncea. Their structures were elucidated using a combination of homo- and heteronuclear 2D NMR techniques (COSY, TOCSY, NOESY, HSQC, and HMBC) and by FABMS. The new compounds were characterized as 3-O-alpha-L-arabinopyranosyl-(1-->2)-[beta-D-galactopyranosyl-(1-->3)]-beta-D-glucuronopyranosylgypsogenin-28-O-beta-D-glucopyranosyl(1-->3)-[beta-D-xylopyranosyl-(1-->4)]-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-fucopyranoside (1), 3-O-alpha-L-arabinopyranosyl-(1-->2)-[beta-D-galactopyranosyl-(1-->3)]-beta-D-glucuronopyranosylgypsogenin-28-O-beta-D-x…

Chemical PhenomenaSpectrophotometry InfraredStereochemistrySaponinPharmaceutical ScienceCaryophyllaceaeUronic acidPlant RootsAnalytical Chemistrychemistry.chemical_compoundTriterpeneDrug DiscoveryTetrasaccharideTrisaccharideOleanolic AcidPharmacologychemistry.chemical_classificationPlants MedicinalMolecular StructureChemistry PhysicalHydrolysisOrganic ChemistrySaponinsTriterpenesXylosideComplementary and alternative medicinechemistryHeteronuclear moleculeMolecular MedicineChromatography Thin LayerTwo-dimensional nuclear magnetic resonance spectroscopyDrugs Chinese HerbalJournal of natural products
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From Molecular Tumor Diagnostics to Individualized Treatment with Phytochemicals Derived from Chinese Herbs

2011

ChemotherapyPredictive markerbiologymedicine.medical_treatmentIndividualized treatmentChinese herbsPharmacologyBiochemistryMultiple drug resistanceGeneticsbiology.proteinmedicineMolecular MedicineEpidermal growth factor receptorBiotechnologyP-glycoproteinForum on Immunopathological Diseases and Therapeutics
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Baudelaire's Influence on Duo Duo's Poetry through Chen Jingrong, a Chinese Woman Poet Translating from French.

2012

As a woman poet, Chen Jingrong’s productions encompassed the whole 20th century: of particular interest are her poetry translations from the French language. Thanks to her translation work, valuable understanding of Charles Baudelaire’s poetry was made available in China, which influenced the Chinese contemporary poet, Duo Duo, when he first started writing poetry during his youth. This paper tries to depict the importance of this contribution of Chen Jingrong and its effect on the process of renovation of the contemporary poetic scene in China.

Chen Jingrong Baudelaire Duo Duo contemporary Chinese poetry translationSettore L-OR/21 - Lingue E Letterature Della Cina E Dell'Asia Sud-Orientale
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L'acqua nei versi di Chen Jingrong

2009

L'intervento analizza l'elemento metaforico legato al concetto di 'acqua' nella scrittura poetica della poetessa cinese Chen Jingrong. The paper takes into consideration the metaphorical element of the concept of "water" in the poetry of the contemporary Chinese woman poet Chen Jingrong

Chen Jingrong acqua e poesia cineseChen Jingrong water and Chinese poetrySettore L-OR/21 - Lingue E Letterature Della Cina E Dell'Asia Sud-Orientale
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Charming Connections: Chen Jingrong's Translations as a Factor of Poetic Influence

2015

L'articolo mette il luce l'influenza che la poesia francese ha nel processo creativo della poetessa Chen Jingrong come derivazione della sua pratica traduttiva dal francese al cinese. The paper describes the influence French poetry has on the poetic production of the woman poet Chen Jingrong depending on her practice as translator from French into Chinese.

Chen Jingrong poesia cinese traduzione poesie BaudelaireChen Jingrong Chinese poetry translation poems by BaudelaireSettore L-OR/21 - Lingue E Letterature Della Cina E Dell'Asia Sud-Orientale
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La gaozhong o scuola secondaria di secondo grado nel sistema scolastico della Repubblica Popolare Cinese

2020

L'articolo inquadra la scuola secondaria di secondo grado, gaozhong, nel sistema scolastico cinese. Il XX secolo in Cina si caratterizza per una successione di trasformazioni epocali che nel tempo hanno cambiato il volto del Paese. In particolare, dopo la conclusione del lungo e contraddittorio decennio della Rivoluzione culturale (1966-1976), che aveva determinato la chiusura delle scuole secondarie di ogni grado e delle università con la successiva dispersione degli studenti nelle aree rurali, è stato necessario ricostruire il sistema scolastico nella sua interezza. Infatti, le scuole non erano più praticabili, molti professori erano stati sottoposti a critica e gli studenti erano stati a…

China educational policylegislazione sull’istruzione cinesepolitica sull’istruzione cineseChina educational legislationgaozhongChinese school systemformazione degli insegnanti cinesiSettore L-OR/21 - Lingue E Letterature Della Cina E Dell'Asia Sud-OrientaleSistema scolastico cineseteacher education
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