Search results for "Chlorides"

showing 10 items of 86 documents

ß-COP mutants show specific high sensitivity to chloride ions.

2021

Coat Protein I (COPI) consists of a complex (coatomer) formed by seven subunits (α-, β-, β’-, γ-, δ-, ε-, and ζ-COP) that is recruited to Golgi membranes to form vesicles that shuttle from the Golgi apparatus to the ER and between Golgi stacks. Recently, it has been described that loss of function mutants of the two Arabidopsis β-COP genes, β1-COP and β2-COP, showed increased sensitivity to salt stress (NaCl). Using a mixture of either Na(+) or Cl(−) salts, we have now found that β-COP mutants are specifically and highly sensitive to chloride ions.

0106 biological sciences0301 basic medicineShort CommunicationMutantArabidopsisSalt (chemistry)Plant ScienceBiology01 natural sciencesChlorideCoatomer Protein03 medical and health sciencessymbols.namesakeChloridesArabidopsismedicinechemistry.chemical_classificationIonsVesicleCOPIGolgi apparatusbiology.organism_classificationhumanitiesProtein Subunits030104 developmental biologyPhenotypechemistryCoatomerMutationsymbolsBiophysics010606 plant biology & botanymedicine.drugProtein BindingPlant signalingbehavior
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Effect of Manganese Chloride and of Cotreatment with Cadmium Chloride on the In Vitro Proliferative, Motile, and Invasive Behavior of MDA-MB231 Breas…

2019

We examined the dose&ndash

0301 basic medicinecadmiumproliferationPharmaceutical ScienceBreast NeoplasmsCadmium chloridemedicine.disease_causeArticleAnalytical ChemistryMetastasislcsh:QD241-44103 medical and health scienceschemistry.chemical_compound0302 clinical medicineBreast cancerCadmium ChlorideChlorideslcsh:Organic chemistryCell Movementbreast cancer cellCell Line TumorDrug DiscoverymedicineHumansSettore BIO/06 - Anatomia Comparata E CitologiaPhysical and Theoretical ChemistrychemotaxisCell ProliferationCell growthOrganic Chemistrymedicine.diseasechemoinvasionIn vitroEpithelium030104 developmental biologymedicine.anatomical_structureManganese CompoundschemistryChemistry (miscellaneous)030220 oncology & carcinogenesisCancer cellCancer researchmanganeseMolecular MedicineFemalechemotaxiCarcinogenesisbreast cancer cellsMolecules
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Effect of loperamide on jejunal electrolyte and water transport, prostaglandin E 2-induced secretion and intestinal transit time in man

1991

Jejunal perfusion was performed in 12 healthy volunteers to evaluate the dose dependent effects of loperamide on intestinal absorption, stimulated secretion and transit. In 6 volunteers intestinal perfusion of the jejunal segment with isotonic NaCl solution was followed by addition of loperamide in increasing doses (2–8 mg·l−1). The volunteers were pretreated with 1 mg·l−1 prostaglandin E2 (PgE2) in the perfusate before addition of 4 mg·l−1 loperamide. Phenolsulphonphtalein (PSP) boluses (2 ml) were given to measure mean transit time (MTT). Loperamide 2 mg·l−1 converted the minor secretion after perfusion with the standard solution (water −1.45 ml·min−1, Na −0.09 and Cl −0.04 mmol·min−1) to…

AdultDiarrheaMalemedicine.medical_specialtyLoperamideAdolescentAbsorption (skin)LoperamideDinoprostoneIntestinal absorptionJejunumChloridesInternal medicinemedicineHumansPharmacology (medical)Prostaglandin E2Gastrointestinal TransitPharmacologyWater transportDose-Response Relationship DrugChemistrySodiumBiological TransportGeneral MedicineWater-Electrolyte BalanceJejunumEndocrinologymedicine.anatomical_structureIntestinal AbsorptionMechanism of actionmedicine.symptomPerfusionmedicine.drugEuropean Journal of Clinical Pharmacology
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PGC-1α Induction in Pulmonary Arterial Hypertension

2012

Idiopathic Pulmonary arterial hypertension (IPAH) is characterized by the obstructive remodelling of pulmonary arteries, and a progressive elevation in pulmonary arterial pressure (PAP) with subsequent right-sided heart failure and dead. Hypoxia induces the expression of peroxisome proliferator activated receptorγcoactivator-1α(PGC-1α) which regulates oxidative metabolism and mitochondrial biogenesis. We have analysed the expression of PGC-1α, cytochrome C (CYTC), superoxide dismutase (SOD), the total antioxidant status (TAS) and the activity of glutathione peroxidase (GPX) in blood samples of IPAH patients. Expression of PGC-1αwas detected in IPAH patients but not in healthy volunteers. Th…

AdultMaleAgingmedicine.medical_specialtyArticle SubjectHypertension PulmonaryPeroxisome proliferator-activated receptorBiologyBiochemistrySuperoxide dismutaseChloridesInternal medicinemedicineHumansFamilial Primary Pulmonary Hypertensionlcsh:QH573-671Heat-Shock ProteinsAgedchemistry.chemical_classificationGlutathione Peroxidaselcsh:CytologySuperoxide DismutaseGlutathione peroxidaseAge FactorsCytochromes cCell BiologyGeneral MedicineHypoxia (medical)Middle Agedmedicine.diseasePulmonary hypertensionPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaEndocrinologymedicine.anatomical_structurechemistryMitochondrial biogenesisHeart failurebiology.proteinVascular resistanceFemaleVascular Resistancemedicine.symptomTranscription FactorsResearch ArticleOxidative Medicine and Cellular Longevity
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Influence of hemostatic agents upon the outcome of periapical surgery: dressings with anesthetic and vasoconstrictor or aluminum chloride

2011

Objective: To evaluate the effects of different hemostatic agents upon the outcome of periapical surgery. Design: A retrospective study was made of patients subjected to periapical surgery between 2006-2009 with the ultrasound technique and using MTA as retrograde filler material. We included patients with a minimum follow-up of 12 months, divided into two groups according to the hemostatic agent used: A) dressings impregnated in anesthetic solution with adrenalin; or B) aluminum chloride paste (Expasyl™). Radiological controls were made after 6 and 12 months, and on the last visit. The global evolution scale proposed by von Arx and Kurt (1999) was used to establish the outcome of periapica…

AdultMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentOdontologíaChlorideHemostaticsYoung AdultChloridesmedicineAluminum ChlorideHumansVasoconstrictor AgentsVasoconstrictor AgentsAnesthetics LocalAluminum CompoundsChildGeneral DentistryAstringentsAgedRetrospective StudiesHemostatic Agentbusiness.industryApicoectomyRetrospective cohort studyMiddle Aged:CIENCIAS MÉDICAS [UNESCO]BandagesCiencias de la saludSurgeryHemostaticsTreatment OutcomeOtorhinolaryngologyAnesthesiaHemostasisApicoectomyAnestheticUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleOral Surgerybusinessmedicine.drug
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Non-classic cystic fibrosis associated with D1152HCFTR mutation

2010

Burgel P-R, Fajac I, Hubert D, Grenet D, Stremler N, Roussey M, Siret D, Languepin J, Mely L, Fanton A, Labbe A, Domblides P, Vic P, Dagorne M, Reynaud-Gaubert M, Counil F, Varaigne F, Bienvenu T, Bellis G, Dusser D. Non-classic cystic fibrosis associated with D1152H CFTR mutation. Background: Limited knowledge exists on phenotypes associated with the D1152H cystic fibrosis transmembrane conductance regulator (CFTR) mutation. Methods: Subjects with a D1152H allele in trans with another CFTR mutation were identified using the French Cystic Fibrosis Registry. Phenotypic characteristics were compared with those of pancreatic insufficient (PI) and pancreatic sufficient (PS) cystic fibrosis (CF)…

AdultMalemedicine.medical_specialtyConsensusPancreatic diseaseAdolescentCystic FibrosisGENETICSmedicine.medical_treatmentCystic Fibrosis Transmembrane Conductance RegulatorCystic fibrosisGastroenterologyMembrane PotentialsCohort StudiesYoung AdultChloridesInterquartile rangeForced Expiratory VolumeInternal medicineCYSTIC_FIBROSISHumansMedicineLung transplantationGenetic Predisposition to DiseaseChildSweatExocrine pancreatic insufficiencyMUTATIONGenetics (clinical)AgedBronchiectasisbiologybusiness.industryHomozygoteMiddle Agedmedicine.diseaseCongenital absence of the vas deferensCystic fibrosis transmembrane conductance regulatorNasal MucosaEndocrinologyAmino Acid SubstitutionChild Preschoolbiology.proteinFemalebusiness
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Hemostatic Agents in Periapical Surgery: A Randomized Study of Gauze Impregnated in Epinephrine versus Aluminum Chloride

2016

Abstract Introduction Adequate bleeding control is essential for the success of periapical surgery. The aim of this study was to evaluate the effects of 2 hemostatic agents on the outcome of periapical surgery and their relationship with patient and teeth parameters. Methods A prospective study was designed with 2 randomized parallel groups, depending on the hemostatic agent used: gauze impregnated in epinephrine (epinephrine group) and aluminum chloride (aluminum chloride group). The analysis of the hemorrhage control was judged before and after the application of the hemostatic agents by the surgeon, and 2 examiners independently recorded it as adequate (complete hemorrhage control) or in…

AdultMalemedicine.medical_specialtyEpinephrineChlorideHemostaticsEndodonticslaw.invention03 medical and health sciences0302 clinical medicineBleeding controlChloridesRandomized controlled triallawmedicineAluminum ChlorideHumansVasoconstrictor Agents030212 general & internal medicineTooth RootAluminum CompoundsProspective cohort studyGeneral DentistryHemostatic Agentbusiness.industryPeriapical Diseases030206 dentistryMiddle AgedSurgeryLogistic ModelsTreatment OutcomeEpinephrineAnesthesiaHemostasisFemalebusinessPeriapical surgerymedicine.drugJournal of Endodontics
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Pain and swelling after periapical surgery related to the hemostatic agent used: anesthetic solution with vasoconstrictor or aluminum chloride.

2011

Objective: To assess pain and swelling in the first 7 days after periapical surgery and their relationship with the agent used for bleeding control. Study Design: A prospective study was conducted between October 2006 and March 2009. Patients subjected to root surgery, who completed the questionnaire and who consented to the postoperative instructions were included in the study. The subjects were divided into two groups according to the hemostatic agent used: A) gauze impregnated with anesthetic solution with vasoconstrictor; or B) aluminum chloride. The patients were administered a questionnaire, and were asked to record the severity of their pain and swelling on a plain horizontal visual …

AdultMalemedicine.medical_specialtyTime FactorsVisual analogue scaleAnalgesicChloridesEdemaMedicineAluminum ChlorideEdemaHumansVasoconstrictor AgentsProspective StudiesProspective cohort studyAluminum CompoundsGeneral DentistryAstringentsAnestheticsHemostatic AgentPain Postoperativebusiness.industryPeriapical Diseases:CIENCIAS MÉDICAS [UNESCO]SurgerySolutionsOtorhinolaryngologyHemostasisAnesthesiaAnestheticUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticleSwellingmedicine.symptomOral Surgerybusinessmedicine.drugMedicina oral, patologia oral y cirugia bucal
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"Identification of mixed bromidochloridotellurate anions in disordered crystal structures of (bdmim)2[TeX2Y4] (X, Y = Br, Cl; bdmim = 1-butyl-2,3-dim…

2013

Abstract The discrete mixed [TeBrxCl6−x]2− anions in their disordered crystal structures have been identified by using the phases prepared by the reaction of 1-butyl-2,3-dimethylimidazolium halogenides (bdmim)X with tellurium tetrahalogenides TeX4 (X = Cl, Br) as examples. Homoleptic (bdmim)2[TeX6] [X = Cl (1), Br (2)] and mixed (bdmim)2[TeBr2Cl4] (3), and (bdmim)2[TeBr4Cl2] (4) are formed depending on the choice of the reagents, and their crystal structures have been determined by single-crystal X-ray diffraction. The coordination environments of tellurium in all hexahalogenidotellurates are almost octahedral. Because of the crystallographic disorder, the mixed [TeBr2Cl4]2− and [TeBr4Cl2]2…

AnionsBromidesModels MolecularMagnetic Resonance SpectroscopyAb initiochemistry.chemical_elementCrystal structureCrystallography X-RaySpectrum Analysis RamanAnalytical Chemistrysymbols.namesakechemistry.chemical_compoundChloridesX-Ray DiffractionHomolepticInstrumentationta116SpectroscopyMolecular StructureChemistryImidazolesAtomic and Molecular Physics and OpticsCrystallographyOctahedronsymbolsTellurium tetrachlorideQuantum TheoryTelluriumRaman spectroscopyTelluriumPowder diffractionSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

2015

Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.

AnionsModels MolecularTrisSteric effectsCrystallography X-RayChlorideCatalysisPhysico-chimie généralechemistry.chemical_compoundChloridesMaterials ChemistrymedicineChimieMoleculeOrganic chemistryta116Ion transporterIon TransportMolecular StructureChemistryArylThioureatransmembrane anion carriersMetals and Alloystransmembrane transportersGeneral ChemistryCombinatorial chemistryTransmembrane proteinSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsChimie organiqueThioureaCeramics and Compositesmedicine.drugChemical Communications
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