6533b82efe1ef96bd1293cef

RESEARCH PRODUCT

Sterically geared tris-thioureas; transmembrane chloride transporters with unusual activity and accessibility

Rakesh PuttreddyHennie ValkenierOndřej JurčekAnthony P. DavisKari RissanenChristopher M. DiasKathryn L. Porter Goff

subject

AnionsModels MolecularTrisSteric effectsCrystallography X-RayChlorideCatalysisPhysico-chimie généralechemistry.chemical_compoundChloridesMaterials ChemistrymedicineChimieMoleculeOrganic chemistryta116Ion transporterIon TransportMolecular StructureChemistryArylThioureatransmembrane anion carriersMetals and Alloystransmembrane transportersGeneral ChemistryCombinatorial chemistryTransmembrane proteinSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsChimie organiqueThioureaCeramics and Compositesmedicine.drug

description

Tris-N-arylthioureas derived in one step from 1,3,5-tris(aminomethyl)-2,4,6-triethylbenzene are remarkably effective anion carriers. With optimised aryl substituents their activities come close to the best currently known, suggesting that they might find use as readily available standards in anion transport research.

https://doi.org/10.1039/c5cc05737j