Search results for "Circulation"

Marche et démences

2008

Resume Objectifs Decrire les troubles de la marche (TM) au cours des demences primitives, leurs consequences et l’interet de leur prevention et reeducation. Methode Analyse des articles les plus pertinents disponibles sur Medline concernant la marche et la demence. Resultats La prevalence des TM et de l’equilibre dans la demence de type Alzheimer varie de 9 a 52 %. Les marches frontale et apraxique y sont decrites. Dans la demence vasculaire, les TM a type de marches hemiparetique, frontale et unsteady, sont observes chez plus de 71 % de patients et sont probablement un marqueur precoce de cette demence. Bien qu’en pratique clinique les TM semblent frequents dans la demence a corps de Lewy …

Transformation synthesis of aluminosilicate SSZ-39 zeolite from ZSM-5 and beta zeolite

2019

Aluminosilicate SSZ-39 zeolite has been successfully prepared by transformation from ZSM-5 and beta zeolite in the presence of N,N-diethyl-cis-2,6-dimethylpiperidinium hydroxide (DMPOH) under hydrothermal conditions. Catalytic tests in the selective catalytic reduction of NOx with NH3 (NH3-SCR) show that the copper-exchanged products synthesized from the interzeolite transformation exhibit excellent catalytic performance.

Fluid resuscitation-related coagulation impairment in a porcine hemorrhagic shock model.

2020

Background Fast and effective treatment of hemorrhagic shock is one of the most important preclinical trauma care tasks e.g., in combat casualties in avoiding severe end-organ damage or death. In scenarios without immediate availability of blood products, alternate regimens of fluid resuscitation represent the only possibility of maintaining sufficient circulation and regaining adequate end-organ oxygen supply. However, the fluid choice alone may affect the extent of the bleeding by interfering with coagulation pathways. This study investigates the impact of hydroxyethyl starch (HES), gelatine-polysuccinate (GP) and balanced electrolyte solution (BES) as commonly used agents for fluid resu…

Effect of fluid resuscitation on cerebral integrity: A prospective randomised porcine study of haemorrhagic shock.

2021

BACKGROUND The treatment of haemorrhagic shock is a challenging task. Colloids have been regarded as standard treatment, but their safety and benefit have been the subject of controversial debates. Negative effects, including renal failure and increased mortality, have resulted in restrictions on their administration. The cerebral effects of different infusion regimens are largely unknown. OBJECTIVES The current study investigated the impact of gelatine-polysuccinate, hydroxyethyl starch (HES) and balanced electrolyte solution (BES) on cerebral integrity, focusing on cerebral inflammation, apoptosis and blood flow in pigs. DESIGN Randomised experimental study. SETTING University-affiliated …

Pathogenesis and molecular mechanisms of anderson–fabry disease and possible new molecular addressed therapeutic strategies

2021

Anderson–Fabry disease (AFD) is a rare disease with an incidenceof approximately 1:117,000 male births. Lysosomal accumulation of globotriaosylceramide (Gb3) is the element characterizing Fabry disease due to a hereditary deficiency α-galactosidase A (GLA) enzyme. The accumulation of Gb3 causes lysosomal dysfunction that compromises cell signaling pathways. Deposition of sphingolipids occurs in the autonomic nervous system, dorsal root ganglia, kidney epithelial cells, vascular system cells, and myocardial cells, resulting in organ failure. This manuscript will review the molecular pathogenetic pathways involved in Anderson–Fabry disease and in its organ damage. Some studies reported that i…

Cross-sectional flow and bed shear stress: application of the depth-averaged momentum equation in a meandering laboratory flume

2014

Dramme, didrammi e tetradrammi di Panormos e a legenda ṣyṣ nel V secolo a.C.: aggiornamenti e riflessioni intorno alle sequenze dei conî

2019

The main objective of this essay is to comment upon the modes of production and the datings of the 5th century BC non-fractional silver coinage bearing the Greek legend ΠΑΝΟΡΜΟΣ (and variants) and the Punic legend ṣyṣ. The reconstruction of the die sequences published by G. Kenneth Jenkins in 1971 and its recent updates will be discussed in detail. As far as the identification of the issuing authority and of the minting place of the coins with legend ṣyṣ is concerned, for a long time to the center of the scientific research interests, only the inferences made from an analysis of the die sequence have been taken into consideration.

Experimentally Induced Biliary Atresia by Means of Rotavirus‐Infection Is Directly Linked to Severe Damage of the Microvasculature in the Extrahepati…

2018

Abstract: Vascular damage has been reported to contribute to atresia formation in several diseases including biliary atresia. This study focused on the extrahepatic biliary plexus in experimental biliary atresia. Newborn BALB/cAnNCrl-pups were infected with rhesus rotavirus within 24 hr after birth to induce experimental biliary atresia. The extrahepatic biliary plexus was examined by confocal microscopy on whole-mount preparations, scored by three independent researchers, and further evaluated at the subcellular level with transmission electron microscopy. Imaging results revealed a progressive destruction of the extrahepatic biliary vascular plexus in the course of experimental biliary at…

Santé et commerce international. Contribution à l'étude de la protection des valeurs non marchandes par le droit du commerce international

2006

Factors contributing to the variability in muscle ageing

2012

a b s t r a c t Ageing is accompanied with a progressive loss of muscle mass and force generating capacity. Ultimately, the muscle wasting and weakness may dramatically impact on mobility and the quality of life, where the elderly has increasing problems with performing activities of daily life, such as rising from a chair or climbing stairs. The rate of structural and functional deterioration of muscle appears to vary considerably between people. Part of the variation in the 'rate of muscle ageing' is attributable to genetic factors, the timing of changes in circulating hormones and the presence or absence of chronic low-grade systemic inflammation. Where an individual cannot change much i…