Search results for "Circulation"
showing 10 items of 1137 documents
Effect of arterial oxygen tension on cerebral blood flow at different levels of arterial PCO2.
1970
Die Wirkung des arteriellen O2-Partialdruckes auf die Durchblutung des Grosshirns, Kleinhirns und Hirnstammes bei normalen und erhohten CO2-Partialdrucken im arteriellen Blut wird an der anaesthesierten Katze untersucht. Die Wirkung des PaO2 ist von der Hohe des PaCO2 abhangig.
A Unified Perspective on the Dynamics of Axisymmetric Hurricanes and Monsoons
2006
Abstract This paper provides a unified perspective on the dynamics of hurricane- and monsoonlike vortices by identifying them as specific limiting cases of a more general flow system. This more general system is defined as stationary axisymmetric balanced flow of a stably stratified non-Boussinesq atmosphere on the f plane. The model is based on the primitive equations assuming gradient wind balance in the radial momentum equation. The flow is forced by heating in the vortex center, which is implemented as relaxation toward a specified equilibrium temperature Te. The flow is dissipated through surface friction, and it is assumed to be almost inviscid in the interior. The heating is assumed …
Analyses of the TRACE V5 capability for the simulation of natural circulation and primary/containment coupling in BDBA condition typical of the MASLWR
2014
In the short term period the use of advanced Small Modular Reactor (SMR) is one of the most promising options for the deployment of nuclear technology. The validation and assessment of the best estimate thermal hydraulic system code TRACE against SMR thermal hydraulic phenomena is a novel effort. In this framework the use of the natural circulation database developed at the OSU-MASLWR test facility, simulating the MASLWR reactor prototype, is of interest for analyses of the TRACE code capability in predicting natural circulation and primary/containment coupled behavior in SMR. The target of this paper is to analyze the TRACE V5 capability for the simulation of natural circulation phenomena,…
Neurons and ECM regulate occludin localization in brain endothelial cells
2000
We report that extracellular matrix and neurons modulate the expression of occludin, one of the main components of tight junctions, by rat brain endothelial cells (RBE4.B). Of the three extracellular matrix proteins which we tested (collagen I, collagen IV, and laminin), collagen IV stimulated at the best the expression of occludin mRNA. The corresponding protein, however, was not synthesized. Significant amounts of occludin accumulated only when RBE4.B cells were cultured on collagen IV-coated inserts, in the presence of cortical neurons, plated on laminin-coated companion wells. Finally, occludin segregated at the cell periphery, only when endothelial cells were co- cultured with neurons …
Anti-fetal immune response mechanisms may be involved in the pathogenesis of placental abruption
2003
Placental abruption is an unpredictable severe complication in pregnancy. In order to investigate the possibility that the activation of the fetal nonadaptive immune system may be involved in the pathogenesis of this disease, IL-6 release from cord blood monocytes was examined by intracellular cytokine staining and flow cytometric analysis. Our results demonstrate that preterm placental abruption (n = 15) in contrast to uncontrollable preterm labor (n = 33) is associated with significantly (P < 0.001) increased release of IL-6 from the fetal monocytes. The same holds true for rhesus disease (n = 9, P < 0.001) that is characterized by a maternal production of antibodies against the rhesus-D …
Trace element systematics of tourmaline in pegmatitic and hydrothermal systems from the Variscan Schwarzwald (Germany): The importance of major eleme…
2013
article An extensive data set on the compositional variation of tourmaline from granitic pegmatites, from migmatitic gneisses and from various types of hydrothermal veins from the Schwarzwald, Germany, is provided. The investigated tourmalines are members of the alkali and X-vacant groups representing mostly dravite- schorl solid solutions with some analyses belonging to the foitite-Mg-foitite series. Oxygen isotope data on quartz-tourmaline pairs indicate formation temperatures between 550 and 350 °C for most of the quartz-tourmaline veins. Most of the tourmalines show strong sector zonation, fractionating certain major (e.g., Na, Mg), minor (e.g., Ti, Ca) and trace elements (e.g., Sr, Pb,…
Hydrodynamic liver gene transfer mechanism involves transient sinusoidal blood stasis and massive hepatocyte endocytic vesicles
2005
The present study contributes to clarify the mechanism underlying the high efficacy of hepatocyte gene transfer mediated by hydrodynamic injection. Gene transfer experiments were performed employing the hAAT gene, and the efficacy and differential identification in mouse plasma of human transgene versus mouse gene was assessed by ELISA and proteomic procedures, respectively. By applying different experimental strategies such as cumulative dose-response efficacy, hemodynamic changes reflected by venous pressures, intravital microscopy, and morphological changes established by transmission electron microscopy, we found that: (a) cumulative multiple doses of transgene by hydrodynamic injection…
Current Status of Knowledge and Critical Issues in Tumor Oxygenation
1998
In 1972 we started the systematic investigation of oxygenation status in (a) experimental tumor systems in rats and mice [e.g., 1–6], (b) in human tumors xenotransplanted into immune-deficient rnu/rnu-rats [e.g., 7–9], (c) in tumors derived from spontaneously tumorigenic or ras-transformed cell lines [10], and (d) in human tumors in situ [e.g., 11–15] under various pathophysiological conditions using polarographic O2 needle electrodes. In the earlier studies a cryospectrophotometric ex vivomicrotechnique was also used that allowed the measurement of HbO2 saturation in individual red blood cells in tumor microvessels [e.g., 16, 17]. Besides polarographic and cryospectrophotometric microtechn…
A Global Climatology of Tropical Moisture Exports
2013
Abstract In a recent paper, a climatology of tropical moisture exports (TMEs) to the Northern Hemisphere (NH) was constructed on the basis of 7-day forward trajectories, started daily from the tropical lower troposphere, which were required to reach a water vapor flux of at least 100 g kg−1 m s−1 somewhere north of 35°N. It was shown that TMEs contribute significantly to regional precipitation. Here, the authors complement and extend this work by (i) using 6-hourly European Centre for Medium-Range Weather Forecasts (ECMWF) Interim Re-Analysis (ERA-Interim) data from 1979 to 2010 instead of the earlier 40-yr ECMWF Re-Analysis (ERA-40), (ii) extending the climatology to the Southern Hemispher…
Vertical grid refinement for stratocumulus clouds in the radiation scheme of a global climate model
2021
Abstract. In this study, we implement a vertical grid refinement scheme in the radiation routine of the global aerosol-climate model ECHAM-HAM, aiming to improve the representation of stratocumulus clouds and address the underestimation of their cloud cover. The scheme is based on a reconstruction of the temperature inversion as a physical constraint for the cloud top. On the refined grid, the boundary layer and the free troposphere are separated and the cloud's layer is made thinner. The cloud cover is re-calculated either by conserving the cloud volume (SC-VOLUME) or by using the Sundqvist cloud cover routine on the new grid representation (SC-SUND). In global climate simulations, we find…