Search results for "Clase"

Villamalea. 1900-1939. Estudio sobre una comunidad rural de La Mancha. Del caciquismo a la aparición de las organizaciones de clase.

1980

El objeto de la Tesis Doctoral es el estudio de una comunidad rural en La Mancha, Villamalea (Albacete) durante el período 1900-1939. El interés por el estudio de Villamalea tiene su base en el fuerte desarrollo político y sindical, como consecuencia de la conciencia política y social, que alcanza su mayor expresión en la década de los años 60 y 70 del siglo XX. El alto nivel de conflictividad con el régimen del general Franco, el arraigo y la extensión de la conciencia de clase de los vecinos, la forma original con que se enfrentaron los problemas económicos y la crisis de la agricultura, las alternativas planteadas a la situación existente y otros hechos acaecidos en la década de los años…

Prácticas docentes para la zoología y botánica en los nuevos planes de estudio.1.

2009

Nuestra propuesta intenta promover el uso de las TIC´s (tecnologías de la información y la comunicación) en las clases prácticas de Zoología y Botánica (dos materias obligatorias para estudiantes de 2º curso de Biología y de Ciencias Ambientales) a través del uso de un DVD interactivo que contiene los materiales para las dos sesiones prácticas, el estudio de la morfología funcional del cráneo de los mamíferos y una salida al campo virtual a un área protegida para reconocer plantas y animales comprendiendo sus relaciones ecológicas en los diferentes hábitats. En el ámbito universitario, estas herramientas informáticas, se pueden emplear como ayuda pedagógica antes o después de la asistencia …

SHRIMP ZIRCON AGES AND PETROLOGY OF LOWER CRUSTAL GRANULITE XENOLITHS FROM THE LETSENG-LA-TERAE KIMBERLITE, LESOTHO: FURTHER EVIDENCE FOR A NAMAQUA-N…

2013

Recrystallized zircons extracted from intermediate granulites of the Letseng-la-Terae Diamond Mine in northeastern Lesotho provide evidence that the Tugela Terrane of the Mesoproterozoic high-grade Namaqua-Natal mobile belt may extend ~200 km farther west than previously thought. The rock-forming minerals in the investigated lower crustal granulites contain garnet, clinopyroxene, plagioclase and quartz or garnet, wollastonite, plagioclase and quartz. Calculated values for peak granulite-facies metamorphism are ~13 kbar and ~850°C. Thermal overprint and therein granulite-facies metamorphism occurred during the late Mesoproterozoic and is documented by SHRIMP metamorphic zircon ages of 1018 ±…

Nitric oxide increases the decay of matrix metalloproteinase 9 mRNA by inhibiting the expression of mRNA-stabilizing factor HuR.

2003

Dysregulation of extracellular matrix turnover is an important feature of many inflammatory processes. Rat renal mesangial cells express high levels of matrix metalloproteinase 9 (MMP-9) in response to inflammatory cytokines such as interleukin-1 beta. We demonstrate that NO does strongly destabilize MMP-9 mRNA, since different luciferase reporter gene constructs containing the MMP-9 3' untranslated region (UTR) displayed significant reduced luciferase activity in response to the presence of NO. Moreover, by use of an in vitro degradation assay we found that the cytoplasmic fractions of NO-treated cells contained a higher capacity to degrade MMP-9 transcripts than those obtained from contro…

La transformación del currículo en una sociedad diversa : ¿quién y cómo se decide el currículum?

2018

The purpose of this article is to show how, in the United States, some states and school districts are transforming their curriculum through ethnic studies. Ethnic studies exists as a result of unequal power relations in which historically marginalized groups have not had the power to define how education will serve their own communities. According to its activists, ethnic studies not only teaches about the cultures of diverse groups, but also reconstructs, the curriculum around the counter-narratives perspectives, epistemologies, and visions of groups that have been treated historically as if their experiences and perspectives were of lesser value. The article begins with a theoretical fra…

Organic Nitrate Therapy, Nitrate Tolerance, and Nitrate-Induced Endothelial Dysfunction: Emphasis on Redox Biology and Oxidative Stress

2015

Abstract Organic nitrates, such as nitroglycerin (GTN), isosorbide-5-mononitrate and isosorbide dinitrate, and pentaerithrityl tetranitrate (PETN), when given acutely, have potent vasodilator effects improving symptoms in patients with acute and chronic congestive heart failure, stable coronary artery disease, acute coronary syndromes, or arterial hypertension. The mechanisms underlying vasodilation include the release of •NO or a related compound in response to intracellular bioactivation (for GTN, the mitochondrial aldehyde dehydrogenase [ALDH-2]) and activation of the enzyme, soluble guanylyl cyclase. Increasing cyclic guanosine-3′,-5′-monophosphate (cGMP) levels lead to an activation of…

Biochemistry and pharmacology of novel anthranilic acid derivatives activating heme-oxidized soluble guanylyl cyclase.

2005

The heme-enzyme soluble guanylyl cyclase (sGC) is an ubiquitous NO receptor, which mediates NO downstream signaling by the generation of cGMP. We studied the mechanism of action of the anthranilic acid derivatives 5-chloro-2-(5-chloro-thiophene-2-sulfonylamino-N-(4-(morpholine-4-sulfonyl)-phenyl)-benzamide sodium salt (HMR1766) (proposed international nonproprietary name, ataciguat sodium) and 2-(4-chloro-phenylsulfonylamino)-4,5-dimethoxy-N-(4-(thiomorpholine-4-sulfonyl)-phenyl)-benzamide (S3448) as a new class of sGC agonists. Both compounds activated different sGC preparations (purified from bovine lung, or crude from human corpus cavernosum) in a concentration-dependent and quickly reve…

Pasajes de París / 5; Urbanismo

2006

Los excluidos, ciudadanos

1998

The evolution of nitric oxide signalling diverges between the animal and the green lineages

2019

AbstractNitric oxide (NO) is a ubiquitous signalling molecule with widespread distribution in prokaryotes and eukaryotes where it is involved in countless physiological processes. While the mechanisms governing nitric oxide (NO) synthesis and signalling are well established in animals, the situation is less clear in the green lineage. Recent investigations have shown that NO synthase, the major enzymatic source for NO in animals, is absent in land plants but present in a limited number of algae. The first detailed analysis highlighted that these new NO synthases are functional but display specific structural features and probably original catalytic activities. Completing this picture, analy…