Search results for "Class"

Residual a posteriori error estimation for frictional contact with Nitsche method

2023

We consider frictional contact problems in small strain elasticity discretized with finite elements and Nitsche method. Both bilateral and unilateral contact problems are taken into account, as well as both Tresca and Coulomb models for the friction. We derive residual a posteriori error estimates for each friction model, following [Chouly et al, IMA J. Numer. Anal. (38) 2018, pp. 921-954]. For the incomplete variant of Nitsche, we prove an upper bound for the dual norm of the residual, for Tresca and Coulomb friction, without any extra regularity and without a saturation assumption. Numerical experiments allow to assess the accuracy of the estimates and their interest for adaptive meshing …

Photoinduced lethal and sublethal toxicity of retene, a polycyclic aromatic hydrocarbon derived from resin acid, to coregonid larvae

2004

A comparative investigation on the acute phototoxicity of retene to vendace (Coregonus albula) and whitefish (C. lavaretus), both having pelagial larvae in spring, was conducted. To test the concept of early warning of sublethal biomarkers in relation to lethality to posthatch stages, we examined the effects of ultraviolet-B (UV-B) and retene on the levels of cytochrome P4501A (CYP1A) and heat shock protein 70 (HSP70) by exposing the animals to elevated levels of these factors for 48 and 72 h, respectively. Whereas UV-B and retene on their own were not lethal, simultaneous retene and UV-B exposure caused very high mortality to both species. The median lethal concentration (LC50; i.e., the c…

Regulation of the HTRA2 Protease Activity by an Inhibitory Antibody-Derived Peptide Ligand and the Influence on HTRA2-Specific Protein Interaction Ne…

2021

The mitochondrial serine protease HTRA2 has many versatile biological functions ranging from being an important regulator of apoptosis to being an essential component for neuronal cell survival and mitochondrial homeostasis. Loss of HTRA2 protease function is known to cause neurodegeneration, whereas overactivation of its proteolytic function is associated with cell death and inflammation. In accordance with this, our group verified in a recent study that the synthetic peptide ASGYTFTNYGLSWVR, encoding the hypervariable sequence part of an antibody, showed a high affinity for the target protein HTRA2 and triggered neuroprotection in an in vitro organ culture model for glaucoma. To unravel t…

Novel VAMPIRE algorithms for quantitative analysis of the retinal vasculature

2013

This paper summarizes three recent, novel algorithms developed within VAMPIRE, namely optic disc and macula detection, arteryvein classification, and enhancement of binary vessel masks, and their performance assessment. VAMPIRE is an international collaboration growing a suite of software tools to allow efficient quantification of morphological properties of the retinal vasculature in large collections of fundus camera images. VAMPIRE measurements are currently mostly used in biomarker research, i.e., investigating associations between the morphology of the retinal vasculature and a number of clinical and cognitive conditions.

Serum omega-3 fatty acids are not associated with age-related macular degeneration

2012

Revue non indexée dans le JCR.; International audience; Evaluation of: Kabasawa S, Mori K, Horie-Inoue K et al. Associations of cigarette smoking but. not serum fatty acids with age-related macular degeneration in a Japanese population. Ophthalmology 118(6), 1082–1088 (2011). Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly. in developed countries. Risk factors for AMD are classified into endogenous nonmodifiable. factors, including genetics and environmental factors such as smoking and dietary habits. Both. epidemiological and experimental studies suggest that dietary omega-3 long-chain fatty acids. would participate to prevent from the develo…

On the use of multi-temporal series of COSMO-SkyMed data for LANDcover classification and surface parameter retrieval over agricultural sites

2011

The objective of this paper is to report on the activities carried out during the first year of the Italian project “Use of COSMO-SkyMed data for LANDcover classification and surface parameters retrieval over agricultural sites” (COSMOLAND), funded by the Italian Space Agency. The project intends to contribute to the COSMO-SkyMed mission objectives in the agriculture and hydrology application domains.

New genera, species and records of Phaneropterinae (Orthoptera, Phaneropteridae) from sub-Saharan Africa

2015

The results of the study of many specimens preserved in different European museums are reported. The tribe Terpnistrini Brunner von Wattenwyl, 1878 is resurrected. The distribution of the following species is enhanced: Pardalotaasymmetrica Karsch, 1896, Diogenadenticulata Chopard, 1954, Diogenafausta (Burmeister, 1838), Plangiopsisadeps Karsch, 1896, Poreuomenasanghensis Massa, 2013 and Tylopsiscontinua (Walker, 1869). Further, for their peculiar characteristics, two African representatives of the American genus Symmetropleura Brunner von Wattenwyl, 1878 are included in two new genera: Symmetrokarschiaafricana (Brunner von Wattenwyl, 1878), comb. n. and Symmetroraggeadirempta (Karsch, 1889)…

Phytochemical investigation of the needles of Abies nebrodensis (Lojac.) Mattei

2019

Abies nebrodensis (Lojac.) Mattei (Pinaceae) is a species living in a very small population only in a confined area of Sicily. In this study, the dichloromethane extract of the leaves was analyzed. Apart from three already known metabolites namely dehydroabietic acid; maltol; and rheosmin, previously detected in other species of Abies, a lanostane derivative was isolated. Its chemical structure was elucidated by means of extensive spectroscopic methods.

Adaptation to world trends : a rereading of the May Fourth Movement radicalization

2013

A double-blind, placebo-controlled comparison of treatment with fluticasone propionate and levocabastine in patients with seasonal allergic rhinitis

1999

Fluticasone propionate aqueous nasal spray (FPANS) is a topically active glucocorticoid which has been successfully used for the treatment of seasonal allergic rhinitis (SAR). Topical levocabastine is a highly selective H1 antagonist which has been proposed as an alternative treatment of SAR. The purpose of this study was to compare the clinical efficacy of two topical nasal treatments, FPANS and levocabastine, in the treatment of SAR. Additionally, the effect of treatments on nasal inflammation was examined during natural pollen exposure. A group of 288 adolescent and adult patients with at least a 2-year history of SAR to seasonal pollens participated in a multicenter, doubleblind, double…