Search results for "Classification"
showing 10 items of 29475 documents
Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and rela…
2016
A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidene)butanoate as an example of a new class of sortase A inhibitors. Other analogues were generated by changing the ethoxycarbonyl function for a carboxy, cyano or amide group, or introducing substituents in the phenyl ring of the ester and acid derivatives. The most active derivative found was 3-oxo-2-(2-(3,4dichlorophenyl)hydrazinylidene)butanoic acid (2b), showing an IC50 value of 50 µM. For a preliminary assessment of their antivirulence properties the new derivatives were tested for their antibiofilm activity. The most active compo…
Signal processing techniques for robust sound event recognition
2019
The computational analysis of acoustic scenes is today a topic of major interest, with a growing community focused on designing machines capable of identifying and understanding the sounds produced in our environment, similar to how humans perform this task. Although these domains have not reached the industrial popularity of other related audio domains, such as speech recognition or music analysis, applications designed to identify the occurrence of sounds in a given scenario are rapidly increasing. These applications are usually limited to a set of sound classes, which must be defined beforehand. In order to train sound classification models, representative sets of sound events are record…
Hétérogénéité spatiale : principes et méthodes
2004
Spatial Heterogeneity : Principles and Methods This article has a dual purpose . First , it describes the main econometric specifications which can be used to represent spatial heterogeneity , reflected in an instability of parameters in space and / or a heteroscedasticity of error terms . Only the specifications valid in cross-section are examined . Second , it explains the links between spatial heterogeneity and autocorrelation , the other major feature of localised data , defined by the absence of independence between geographical observations . In particular , we look at the extent to which traditional tests of heteroscedasticity or instability need to be amended to take account of spat…
Sex and sexual ornamentation associated with survival of the cyprinid fish, Rutilus rutilus, under disease stress
2013
By conveying information of disease resistance, sexual signals may be used as cues for adaptive mate choice. Here we report observations on survival of laboratory-maintained, wild-collected, sexually mature, ready-to-spawn cyprinid fish, Rutilus rutilus (roach), under accidental epidemic attributed to Flavobacterium psychrophilum, diagnosed using species-specific PCR. The fish were maintained in a single tank. During the 27 days observation period, both the proportion of fish surviving the infection as well as the length-adjusted mean survival time of the fish that died was the highest among the high-ornamented males with large breeding tubercles, intermediary among the low-ornamented males…
Growth and Physiological Performance of a Coastal Species Trifolium fragiferum as Affected by a Coexistence with Trifolium repens, NaCl Treatment and…
2021
The aim of the present study was to analyze the growth and physiological performance of two coexisting species, Trifolium fragiferum, and Trifolium repens, under the effect of NaCl and rhizobial symbiosis. Seeds of T. fragiferum and T. repens were collected from populations in the wild, and plants were cultivated in an automated greenhouse, two plants per container. Three basic types of planting were performed: (1) both plants were T. fragiferum (single species), (2) one T. fragiferum and one T. repens (species coexistence), (3) both plants were T. repens (single species). For every basic type, three subtypes were made: (1) non-inoculated, (2) inoculated with rhizobia taken from T. fargifer…
Remote Sensing of 3-D Geometry and Surface Moisture of a Peat Production Area Using Hyperspectral Frame Cameras in Visible to Short-Wave Infrared Spe…
2016
Miniaturized hyperspectral imaging sensors are becoming available to small unmanned airborne vehicle (UAV) platforms. Imaging concepts based on frame format offer an attractive alternative to conventional hyperspectral pushbroom scanners because they enable enhanced processing and interpretation potential by allowing for acquisition of the 3-D geometry of the object and multiple object views together with the hyperspectral reflectance signatures. The objective of this investigation was to study the performance of novel visible and near-infrared (VNIR) and short-wave infrared (SWIR) hyperspectral frame cameras based on a tunable Fabry–Pérot interferometer (FPI) in measuring a 3-D digital sur…
Overexpression of SAMDC1 gene in Arabidopsis thaliana increases expression of defense-related genes as well as resistance to Pseudomonas syringae and…
2014
It has been previously described that elevation of endogenous spermine levels in Arabidopsis could be achieved by transgenic overexpression of S-Adenosylmethionine decarboxylase (SAMDC) or Spermine synthase (SPMS). In both cases, spermine accumulation had an impact on the plant transcriptome, with up-regulation of a set of genes enriched in functional categories involved in defense-related processes against both biotic and abiotic stresses. In this work, the response of SAMDC1-overexpressing plants against bacterial and oomycete pathogens has been tested. The expression of several pathogen defense-related genes was induced in these plants as well as in wild type plants exposed to an exogeno…
Cross validation of hard-copy and web-based formats of the Sport Imagery Ability Measure
2018
The purpose of this multi-sample study was to examine the psychometric characteristics, factor structure, and measurement invariance of the hard-copy and web-based versions of a measure of sport imagery ability, termed Sport Imagery Ability Measure (SIAM). In the first sample, Spanish athletes (N = 274, 161 men, 113 women, Mage = 21.91, SD = 6.67) completed a hard-copy version of the SIAM. A newly developed web-based version of the SIAM was cross validated in an independent group (N = 266, 147 men, 119 women, Mage = 25.93, SD = 9.84). A small group of participants (n = 16) completed both versions. Exploratory structural equation modelling and confirmatory factor analysis of the data from th…
Efficient regio- and stereoselective access to novel fluorinated ?-aminocyclohexanecarboxylates
2013
A regio- and stereoselective method has been developed for the synthesis of novel fluorinated 2-aminocyclohexanecarboxylic acid derivatives with the fluorine attached to position 4 of the ring. The synthesis starts from either cis- or trans-β-aminocyclohex-4-enecarboxylic acids and involves regio- and stereoselective transformation of the ring C–C double bond through iodooxazine formation and hydroxylation, followed by hydroxy–fluorine or oxo–fluorine exchange.
Enameloid microstructure in the oldest known chondrichthyan teeth
2009
Botella, H., Donoghue, P.C.J and Martinez-Perez, C. 2009. The enameloid microstructure of the oldest known chondrichthyan teeth. — Acta Zoologica (Stockholm) 90 (Suppl. 1): 103‐108 Previous studies on tooth enameloid microstructure in several chondrichthyan taxa spanning the phylogeny of the group provided support for the homology of chondrichthyan tooth enameloid. This hypothesis requires that a single crystallite enameloid (SCE) monolayer must be present in the teeth of the most primitive chondrichthyan. However, the dental microstructure of the earliest sharks has yet to be investigated. We have studied the tooth enameloid microstructure of the two oldest tooth-bearing shark species curr…