Search results for "CoDi"
showing 10 items of 1391 documents
L'efficacia territoriale delle costituzioni imperiali nella tarda antichità. La questione del dualismo legislativo da Diocleziano al Codex Theodosian…
Il periodo temporale in cui si inserisce il tema trattato è quello tardoimperiale (dalla fine del III secolo alla metà del V secolo d.C.). A seguito della riorganizzazione amministrativa dell'impero in una pars Occidentis e in una pars Orientis, rette da due imperatori, la dottrina si è posta il problema dell'efficacia territoriale delle leges generales nello spazio e, in particolare, se la lex generalis di un Augusto fosse efficace soltanto nei territori governati da quest'ultimo o se lo fosse (e in che modo, cioè ipso iure o previo atto di ricezione e conferma) anche nei territori retti dal collega. Questo è il problema del dualismo legislativo. Attraverso l'esame di un gran numero di cos…
Análisis molecular de la valoración del intervalo de tiempo óptimo entre la administración de acetato de triptorelina y la punción folicular en los t…
2023
Los fármacos análogos de la GnRH y la hCG han demostrado ser igualmente eficaces en la activación de la cascada de intermediarios de la maduración final ovocitaria que ocurre tras el estímulo ovulatorio. Sin embargo, su mecanismo de acción y por tanto los perfiles hormonales hallados tras el estímulo de los dos fármacos son muy diferentes. El tiempo más adecuado para programar la recolección ovocitaria tras la administración de acetato de triptorelina podría no ser 36 horas como ampliamente se ha pautado en los tratamientos de FIV con hCG. Este intervalo de tiempo es sumamente importante para obtener la mayor proporción posible de ovocitos MII porque procesos como el inicio de la luteinizac…
I licenziamenti nel contesto della liquidazione giudiziale
2019
Nella legge fallimentare (r.d. n. 267/1942), nessuna disposizione si rivolgeva espressamente ai contratti di lavoro ancora in corso di esecuzione. Sicché ai licenziamenti «causati» da un fallimento sono state applicate le regole lavoristiche, «adattate», con non poche forzature, alla fattispecie del fallimento. Il Codice della crisi e dell’insolvenza (d.lgs. n. 14/2019), che sostituisce il fallimento con una nuova procedura concorsuale, introduce, per la prima volta, una disposizione (l’art. 189) dedicata ai rapporti di lavoro coinvolti da una liquidazione giudiziale. Il saggio analizza le regole che disciplinano le diverse forme di risoluzione dei contratti di lavoro – recesso del curatore…
Role of RNA Motifs in RNA Interaction with Membrane Lipid Rafts: Implications for Therapeutic Applications of Exosomal RNAs
2021
RNA motifs may promote interactions with exosomes (EXO-motifs) and lipid rafts (RAFT-motifs) that are enriched in exosomal membranes. These interactions can promote selective RNA loading into exosomes. We quantified the affinity between RNA aptamers containing various EXO- and RAFT-motifs and membrane lipid rafts in a liposome model of exosomes by determining the dissociation constants. Analysis of the secondary structure of RNA molecules provided data about the possible location of EXO- and RAFT-motifs within the RNA structure. The affinity of RNAs containing RAFT-motifs (UUGU, UCCC, CUCC, CCCU) and some EXO-motifs (CCCU, UCCU) to rafted liposomes is higher in comparison to aptamers withou…
Air Pollution: Role of Extracellular Vesicles-Derived Non-Coding RNAs in Environmental Stress Response
2023
Air pollution has increased over the years, causing a negative impact on society due to the many health-related problems it can contribute to. Although the type and extent of air pollutants are known, the molecular mechanisms underlying the induction of negative effects on the human body remain unclear. Emerging evidence suggests the crucial involvement of different molecular mediators in inflammation and oxidative stress in air pollution-induced disorders. Among these, non-coding RNAs (ncRNAs) carried by extracellular vesicles (EVs) may play an essential role in gene regulation of the cell stress response in pollutant-induced multiorgan disorders. This review highlights EV-transported ncRN…
Vertaileva analyysi live coding -sävellysympäristöihin
2010
Tässä tutkielmassa selvitetään mitä live coding on ja tutustutaan nel- jään live coding -sävellysympäristöön aloittelijan näkökulmasta. Ohjelmia vertail- laan neljän piirteen avulla ensisijaisesti käytettävyyden ja helpon omaksuttavuuden kannalta.
Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD
2021
Background and aim: Coffee intake exerts protective effects against non-alcoholic fatty liver disease (NAFLD), although without fully cleared mechanisms. In this study we aimed to assess whether coffee consumption may influence the expression of long non-coding RNAs (lncRNAs) in the liver. Methods: C57BL/6J mice were fed a 12-week standard diet (SD), high-fat diet (HFD) or HFD plus decaffeinated coffee solution (HFD + coffee). Expression of specific lncRNAs involved in NAFLD was analyzed by real-time PCR. For the most differentially expressed lncRNAs, the analysis was also extended to their mRNA targets. Results: Decaffeinated coffee intake reduced body weight gain, prevented NAFLD, lowered…
Long non-coding RNAs during embryogenesis of the sea urchin
2014
Intriguing studies suggest that long non-coding RNAs (lncRNAs) tend to act in cis with neighboring protein-coding genes. Based on this notion, we assessed whether lncRNAs originate from adjacent genomic regions of selected protein-coding genes, such as early-H2A histone and strim1, that play important functions during development of the sea urchin Paracentrotus lividus. Downregulation of H2A expression relies on the sns5 chromatin insulator placed at the 3'-end of H2A. Northern blot hybridization show that a lncRNA (of ~600 nt), not overlapping with the H2A mRNA, is transcribed from sns5, following H2A expression. The strim1 locus encodes the first echinoderm TRIM-containing factor which fu…
Molecular cloning and characterization of the complementary DNA coding for the B-chain of murine Clq
1989
AbstractcDNA clones coding for the B-chain of murine Clq were isolated from a mouse macrophage library. The characterized clones include the total coding region plus a leader sequence. High homology was found with human Clq B-chain in the coding region (81%). Northern blot analysis of total RNA from different tissues of Balb/c mice showed one band of approximately 1.2 kb. The highest signal was found in RNA preparations of thioglycolate-activated peritoneal macrophages. The probe also hybridized with mRNA from spleen, thymus and heart. Extremely weak signals were found in liver, kidney, lung and intestine tissues.
Neural generators of the frequency-following response elicited to stimuli of low and high frequency: A magnetoencephalographic (MEG) study.
2021
The frequency-following response (FFR) to periodic complex sounds has gained recent interest in auditory cognitive neuroscience as it captures with great fidelity the tracking accuracy of the periodic sound features in the ascending auditory system. Seminal studies suggested the FFR as a correlate of subcortical sound encoding, yet recent studies aiming to locate its sources challenged this assumption, demonstrating that FFR receives some contribution from the auditory cortex. Based on frequency-specific phase-locking capabilities along the auditory hierarchy, we hypothesized that FFRs to higher frequencies would receive less cortical contribution than those to lower frequencies, hence supp…