Search results for "CoV"

showing 10 items of 9749 documents

Zur protonenkatalysierten Aralkylierung von 1,2,3-Trimethylindol und 1,2,3,4-Tetrahydrocarbazol mit Arylaldehyden

1987

1,2,3-Trimethylindol (2) liefert mit Benzaldehyden die Kondensationsprodukte 5 und 6, wahrend aus den NH-Indolen 1 und 3 die Verbindungen 7 und 8 entstehen. Proton-catalyzed Aralkylation of 1,2,3-Trimethylindole and 1,2,3,4-Tetrahydrocarbazole with Arylaldehydes Reaction of 1,2,3-trimethylindole (2) with benzaldehydes leads to the condensation compounds 5 and 6, the NH-indoles 1 and 3, however, give 7 and 8.

Acid catalysisBicyclic moleculeChemistryStereochemistryInfraredDrug DiscoveryCondensationPolymer chemistryPharmaceutical ScienceNuclear magnetic resonance spectroscopyArchiv der Pharmazie
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Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017

2019

Abstract The endophytic fungus Cladosporium sphaerospermum WBS017 was obtained from healthy bulbs of Fritillaria unibracteata var. wabuensis. Fermentation of C. sphaerospermum on solid rice medium yielded three new hybrid polyketides, cladosins L−N (1–3), and a known derivative cladodionen (4). Further cultivation of this fungus on white bean medium afforded an additional new hybrid polyketide, cladosin O (5) along with three known analogues (6–8). The structures of the new compounds were elucidated using a combination of NMR and HRESIMS data. The absolute configurations of compounds 2 and 3 were determined by Mosher’s method and TDDFT-ECD calculations. All isolated compounds were evaluated…

Acinetobacter baumanniiStaphylococcus aureusAntifungal AgentsUstilagoStereochemistryAntineoplastic AgentsMicrobial Sensitivity TestsSaccharomyces cerevisiaeFungusmedicine.disease_cause01 natural sciencesMiceStructure-Activity Relationship03 medical and health sciencesPolyketideCell Line TumorDrug DiscoveryEnterococcus faecalisUstilagomedicineAnimalsDensity Functional TheoryCell Proliferation030304 developmental biologyPharmacology0303 health sciencesDose-Response Relationship DrugMolecular Structurebiology010405 organic chemistryChemistryOrganic ChemistryFritillaria unibracteataMycobacterium tuberculosisGeneral Medicinebiology.organism_classificationAntimicrobialAnti-Bacterial Agents0104 chemical sciencesStaphylococcus aureusPolyketidesPseudomonas aeruginosaFermentationDrug Screening Assays AntitumorAntibacterial activityCladosporiumEuropean Journal of Medicinal Chemistry
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Mini-COVIDNet: Efficient Lightweight Deep Neural Network for Ultrasound Based Point-of-Care Detection of COVID-19

2021

Lung ultrasound (US) imaging has the potential to be an effective point-of-care test for detection of COVID-19, due to its ease of operation with minimal personal protection equipment along with easy disinfection. The current state-of-the-art deep learning models for detection of COVID-19 are heavy models that may not be easy to deploy in commonly utilized mobile platforms in point-of-care testing. In this work, we develop a lightweight mobile friendly efficient deep learning model for detection of COVID-19 using lung US images. Three different classes including COVID-19, pneumonia, and healthy were included in this task. The developed network, named as Mini-COVIDNet, was bench-marked with …

Acoustics and UltrasonicsCoronavirus disease 2019 (COVID-19)Computer sciencePoint-of-Care SystemsLatency (audio)detectionlung ultrasound (US) imaging01 natural sciences0103 physical sciencesImage Interpretation Computer-AssistedComputer-Assisted/methodsHumansElectrical and Electronic Engineering010301 acousticsInstrumentationImage InterpretationPoint of careUltrasonographyArtificial neural networkbusiness.industrySARS-CoV-2Deep learningImage Interpretation Computer-Assisted/methodsVDP::Technology: 500COVID-19deep learningUltrasonography/methodsLung ultrasoundCoronavirusTask (computing)point-of-care testingSoftware deploymentEmbedded systemCOVID-19/diagnostic imagingArtificial intelligencebusiness
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Short and Efficient Chemoenzymatic Synthesis of Goniothalamin.

2004

A high-yielding three-step synthesis of goniothalamin involving an enzymatic kinetic resolution in the presence of vinyl acrylate followed by ring-closing metathesis is discussed.

AcrylateOrganic ChemistrySettore CHIM/06 - Chimica OrganicaGeneral MedicineMetathesisBiochemistryKinetic resolutiongoniothalaminchemistry.chemical_compoundchemistryDrug DiscoverylipaseOrganic chemistrydelta-lactoneChemInform
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Application of LA-ICP-MS as a rapid tool for analysis of elemental impurities in active pharmaceutical ingredients.

2014

The control of inorganic contaminants in active pharmaceutical ingredients has a significant role in the quality control of drug products. The concentration limits for metal residues in drug products have been defined by various regulatory guidelines. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a powerful and fast analytical technique for multi-elemental analysis. A disadvantage in using LA-ICP-MS method is the lack of matrix reference materials for validation and calibration purposes. This article focuses on the handling strategy of laboratory-made matrix calibration standards for the quantification of elemental impurities in an active pharmaceutical ingredie…

Active ingredientChromatographyChemistryLaser ablation inductively coupled plasma mass spectrometryClinical BiochemistryAnalytical techniqueAnalytical chemistryPharmaceutical ScienceAnalytical ChemistryMatrix (chemical analysis)Pharmaceutical PreparationsLa icp msSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationDrug DiscoveryCalibrationInorganic contaminantsElemental impuritiesDrug ContaminationSpectroscopyJournal of pharmaceutical and biomedical analysis
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Renal Function Recovery Strategies Following Marathon in Amateur Runners

2022

Long distance races have a physiological impact on runners. Up to now, studies analyzing these physiological repercussions have been mainly focused on muscle and cardiac damage, as well as on its recovery. Therefore, a limited number of studies have been done to explore acute kidney failure and recovery after performing extreme exercises. Here, we monitored renal function in 76 marathon finishers (14 females) from the day before participating in a marathon until 192 h after crossing the finish line (FL). Renal function was evaluated by measuring serum creatinine (sCr) and the glomerular filtration rate (GFR). We randomly grouped our cohort into three intervention groups to compare three dif…

Active recoveryMarathonMatemáticasPhysiologyPhysiology (medical)educationGlomerular filtration ratehuman activitiesPassive recoveryAcute kidney injuryFrontiers in Physiology
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Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina

2020

This work addresses the way in which Argentine Fat Activism has developed, in recent years, the demand for depathologization of fatness, taking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. First, the contemporary fat body is described in terms of stigma and discrimination, especially in the health field. Then, they refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspective, Fat Studies and Fat Activism. Lastly, a series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were considered, …

Activismo gordo en Argentina Contrera [1137-7038 8537 Arxius de sociologia 562372 2020 42 7674040 Contra la patologización intensiva en términos de derechos humanos]in recent yearsDespatologización.Human RightsFat Studiesespecially in the health field. Thenthe contemporary fat body is described in terms of stigma and discriminationthey refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspectivea series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were consideredCOVID-19:SOCIOLOGÍA [UNESCO]and highlights the innovation of the local turn in the current context of pandemic. Estudios Sobre GorduraActivismo Gordo1137-7038 8537 Arxius de sociologia 562372 2020 42 7674040 Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina ContreraDerechos HumanosDepathologization 175 188focusing on the claim of depathologizationUNESCO::SOCIOLOGÍAFat Studies and Fat Activism. Lastlythe demand for depathologization of fatnesstaking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. FirstFat ActivismLaura This work addresses the way in which Argentine Fat Activism has developed
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Evapotranspiration from an Olive Orchard using Remote Sensing-Based Dual Crop Coefficient Approach

2013

A remote sensing-based approach to estimate actual evapotranspiration (ET) was tested in an area covered by olive trees and characterized by Mediterranean climate. The methodology is a modified version of the standard FAO-56 dual crop coefficient procedure, in which the crop potential transpiration, T p, is obtained by directly applying the Penman-Monteith (PM) equation with actual canopy characteristics (i.e., leaf area index, albedo and canopy height) derived from optical remote sensing data. Due to the minimum requirement of in-situ ancillary inputs, the methodology is suitable also for applications on large areas where the use of tabled crop coefficient values become problematic, due to…

Actual evapotranspirationCanopyEddy covarianceAlbedoPlant transpiration; Optical remote sensing; Dual crop coefficient; Actual evapotranspirationOlive treesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeCrop coefficientDual crop coefficientEvapotranspirationOptical remote sensingPlant transpirationSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliEnvironmental scienceLeaf area indexWater Science and TechnologyCivil and Structural EngineeringTranspirationRemote sensingWater Resources Management
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The impact of in-canopy wind profile formulations on heat flux estimation in an open orchard using the remote sensing-based two-source model

2010

Abstract. For open orchard and vineyard canopies containing significant fractions of exposed soil (>50%), typical of Mediterranean agricultural regions, the energy balance of the vegetation elements is strongly influenced by heat exchange with the bare soil/substrate. For these agricultural systems a "two-source" approach, where radiation and turbulent exchange between the soil and canopy elements are explicitly modelled, appears to be the only suitable methodology for reliably assessing energy fluxes. In strongly clumped canopies, the effective wind speed profile inside and below the canopy layer can strongly influence the partitioning of energy fluxes between the soil and vegetation co…

Actual evapotranspirationEddy covarianceSensible heatlcsh:TechnologyWind speedlcsh:TD1-1066law.inventionWind profile power lawlawSemi-arid areaTwo-source energy balanceSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliLeaf area indexlcsh:Environmental technology. Sanitary engineeringlcsh:Environmental sciencesRemote sensinglcsh:GE1-350lcsh:THigh spatial resolutionSettore ICAR/02 - Costruzioni Idrauliche E Marittime E Idrologialcsh:Geography. Anthropology. RecreationVegetationHeat fluxlcsh:GScintillometerEnvironmental scienceSparse canopyWind speed extinction
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Comparing actual evapotranspiration and plant water potential on a vineyard

2011

Agricultural water requirement in arid and semi-arid environments represents an important fraction of the total water consumption, suggesting the need of appropriate water management practices to sparingly use the resource. Furthermore the quality and quantity of some crops products, such as grape, is improved under a controlled amount of water stress. The latter is related, on a side to actual evapotranspiration (ET) through water demand, on the other side to plant water content through leaf water potential. Residual energy balance approaches based on remote sensing allow to estimate the spatial distribution of daily actual ET at plant scale, representing an useful tool to detect its spati…

Actual evapotranspirationHydrologyIrrigationPlant water potentialSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaEddy covarianceEnergy balanceSurface energy balanceSettore AGR/03 - Arboricoltura Generale E Coltivazioni Arboreesurface energy balance actual evapotranspiration plant water potentialEvapotranspirationFarm waterEnvironmental scienceSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliSpatial variabilityIrrigation managementWater content
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