Search results for "Coherence"

showing 10 items of 905 documents

Factors predicting normal visual acuity following anatomically successful macular hole surgery

2021

Purpose: To assess the incidence of normal vision following anatomically successful macular hole surgery and associated clinical variables. Methods: Multicentre, retrospective chart review. Preoperative, intraoperative and postoperative clinical data were extracted from electronic medical records from seven European vitreoretinal units. Inclusion criteria were as follows: eyes undergoing primary vitrectomy for idiopathic full-thickness macular hole from January 2015 to January 2018; postoperative macular hole closure confirmed by spectral domain optical coherence tomography (OCT); preoperative pseudophakia or phakic eyes receiving combined cataract surgery; one-year follow-up. The primary o…

Malemedicine.medical_specialtyMultivariate analysisVisual acuitygenetic structuresPseudophakiamacular hole closuremedicine.medical_treatmentVisual AcuityvitrectomyVitrectomyTime-to-Treatment03 medical and health sciences0302 clinical medicinefull-thickness macular hole; idiopathic macular hole; macular hole closure; macular hole surgery; vitrectomymedicineFull-thickness macular holeHumansMacular holeAgedRetrospective Studiesfull-thickness macular holeidiopathic macular holebusiness.industryGeneral MedicineOdds ratioCataract surgeryMiddle Agedmedicine.diseaseRetinal Perforationseye diseasesConfidence intervalSurgeryOphthalmologyTreatment Outcomemacular hole surgery030221 ophthalmology & optometryFemalesense organsmedicine.symptombusiness030217 neurology & neurosurgeryTomography Optical CoherenceFollow-Up Studies
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Choroidal osteoma with choroidal excavation and associated neovascular membrane: An OCT-angiography study.

2017

Abstract Clinical case A case is presented of a unilateral choroidal osteoma with choroidal excavation and associated neovascular membrane that was studied using OCT-angiography. The OCT and OCT-angiography revealed an area of choroidal excavation and an active neovascular membrane. Three doses of aflibercept were administered to the patient, which stabilized the neovascularisation. Discussion OCT-angiography was used to analyze the morphology of the superficial vascular network of the osteoma, as well as to monitor the evolution of the neovascular membrane.

Malemedicine.medical_specialtyNeovascular membranegenetic structures03 medical and health sciences0302 clinical medicineOct angiographyOphthalmologymedicineHumansOsteomaAfliberceptbusiness.industryChoroid NeoplasmsAngiographyOsteomaChoroid DiseasesGeneral MedicineChoroidal osteomaMiddle Agedmedicine.diseaseChoroidal Neovascularizationeye diseasesChoroidal excavationbody regionsVascular network030221 ophthalmology & optometrysense organsClinical casebusinessTomography Optical Coherence030217 neurology & neurosurgerymedicine.drug
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Prophylaxis of Pseudophakic Cystoid Macular Edema with Intraoperative Pegaptanib

2011

The purpose of this study was to determine the efficacy of an intraoperative intravitreal pegaptanib injection during phacoemulsification in preventing the development of pseudophakic cystoid macular edema (CME) following cataract surgery.This prospective, controlled pilot study was carried out at the Department of Ophthalmology, Nuevo Hospital Universitario y Politécnico La Fe, Valencia (Spain). Five hundred patients with cataract and healthy retina were included in the study. Patients were assigned in a 1:1 ratio to receive an intraoperative intravitreal pegaptanib injection (n=250) or not (control group, n=250) associated with standardized phacoemulsification surgery and postoperative tr…

Malemedicine.medical_specialtyPseudophakiagenetic structuresPegaptanibmedicine.medical_treatmentPilot ProjectsMacular EdemaHospitals UniversityPostoperative treatmentOphthalmologymedicineHumansPharmacology (medical)Prospective StudiesMacular edemaAgedAged 80 and overPharmacologyPhacoemulsificationSurgical complicationbusiness.industryIncidence (epidemiology)Outcome measuresPhacoemulsificationAptamers NucleotideCataract surgerymedicine.diseaseeye diseasesSurgeryOphthalmologyTreatment OutcomeSpainIntravitreal InjectionsFemalesense organsbusinessTomography Optical CoherenceFollow-Up Studiesmedicine.drugJournal of Ocular Pharmacology and Therapeutics
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Relationship among Corneal Biomechanics, Refractive Error, and Axial Length

2014

Purpose To evaluate the relationship between different ocular and corneal biomechanical parameters in emmetropic and ametropic healthy white children. Methods This study included 293 eyes of 293 healthy Spanish children (135 boys and 158 girls), ranging in age from 6 to 17 years. Subjects were divided according to the refractive error: control (emmetropia, 99 children), myopia (100 children), and hyperopia (94 children) groups. In all cases, corneal hysteresis (CH) and corneal resistance factor (CRF) were evaluated with the Ocular Response Analyzer system. Axial length (AL) and mean corneal power were also measured by partial coherence interferometry (IOLMaster), and central corneal thickne…

Malemedicine.medical_specialtyRefractive errorIntraocular pressureocular parametersAdolescentgenetic structuresAnterior ChamberVisual AcuityEmmetropiaCorneachildrenOphthalmologyHumansMedicinerefractive errorChildIntraocular PressureDioptreÓpticabusiness.industryBiomechanicsHigh myopiaAxial lengthElastic TissueRefractive Errorsmedicine.diseaseeye diseasesBiomechanical PhenomenaAxial Length EyeOphthalmologyCross-Sectional Studiesagecorneal biomechanical propertiesRegression AnalysisOptometryFemaleMultiple linear regression analysissense organsbusinessTomography Optical CoherenceOptometryOptometry and Vision Science
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Optical Coherence Tomography Versus Intravascular Ultrasound to Evaluate Coronary Artery Disease and Percutaneous Coronary Intervention

2013

ObjectivesWe compared intravascular ultrasound (IVUS) and 2 different generations of optical coherence tomography (OCT)—time-domain OCT (TD-OCT) and frequency-domain OCT (FD-OCT)—for the assessment of coronary disease and percutaneous coronary intervention (PCI) using stents.BackgroundOCT is a promising light-based intravascular imaging modality with higher resolution than IVUS. However, the paucity of data on OCT image quantification has limited its application in clinical practice.MethodsA total of 227 matched OCT and IVUS pull backs were studied. One hundred FD-OCT and IVUS pull backs in nonstented (n = 56) and stented (n = 44) vessels were compared. Additionally, 127 matched TD-OCT and …

Malemedicine.medical_specialtyTime Factorsgenetic structuresmedicine.medical_treatmentTreatment outcomeSeverity of Illness Indexintravascular ultrasoundCoronary RestenosisCoronary artery diseaseOptical coherence tomographyPredictive Value of TestsNeointimaIntravascular ultrasoundmedicineHumanscardiovascular diseasesUltrasonography InterventionalAgedCell ProliferationAnalysis of VarianceHyperplasiaoptical coherence tomographymedicine.diagnostic_testbusiness.industrypercutaneous coronary interventionCoronary StenosisPercutaneous coronary interventionMiddle Agedequipment and suppliesmedicine.diseaseCoronary Vesselseye diseasesTreatment Outcomesurgical procedures operativeLinear ModelsFemaleStentssense organsTomographyRadiologyUltrasonographybusinessCardiology and Cardiovascular MedicineTomography Optical CoherenceJACC: Cardiovascular Interventions
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ANATOMICAL AND FUNCTIONAL OUTCOMES OF SYMPTOMATIC IDIOPATHIC VITREOMACULAR TRACTION

2016

To describe the natural history of eyes with symptomatic idiopathic vitreomacular traction (VMT).Retrospective multicenter study of 168 eyes with spectral-domain optical coherence tomography (SD-OCT) findings consistent with idiopathic VMT. All eyes were graded according to SD-OCT findings. Grade 1 was defined as incomplete cortical vitreous separation with foveal attachment. Grade 2 was defined as Grade 1 plus intraretinal cysts or clefts. Grade 3 was defined as Grade 2 plus a foveal detachment. All patients were followed for at least 6 months.There were 168 patients (51 men) with a mean age of 68.8 ± 10.7 years. Patients were followed for a mean of 22.7 ± 20.1 months. The mean duration of…

Malemedicine.medical_specialtyVisual acuitygenetic structuresRemission SpontaneousVisual AcuityTissue AdhesionsVitreomacular tractionVitreous Detachment03 medical and health scienceschemistry.chemical_compound0302 clinical medicineFibrinolytic AgentsRetinal DiseasesVitrectomyOphthalmologymedicineHumansMedical historyFibrinolysin030212 general & internal medicineMacular holeAgedRetrospective StudiesSlit Lampbusiness.industryOcriplasminGeneral MedicineRetinal Perforationsmedicine.diseasePeptide Fragmentseye diseasesSurgeryNatural historyOphthalmologychemistry030221 ophthalmology & optometryFemalesense organsmedicine.symptombusinessTomography Optical CoherenceNatural history studyFibrinolytic agentRetina
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Retinal nerve fibre layer and brain grey substance as early prognostic factors for disability in multiple sclerosis.

2012

We read with interest the article by Bock et al ,1 in which the association between retinal nerve fibre layer (RNFL) and total macular volume (TMV) was analysed by optical coherence tomography (OCT) and contrast sensitivity was measured by functional acuity contrast testing in relapsing-remitting multiple sclerosis (MS) patients. The authors found that the functional contrast vision in MS is influenced by morphological changes in the anterior visual pathway. This work emphasised that contrast sensitivity is reduced in MS, and that RNFL and TMV, as morphological measures of retinal axon loss, are predictors of contrast sensitivity. Ophthalmological examinations were the basis of the Bock et …

Malemedicine.medical_specialtygenetic structuresAnterior Visual Pathwaymedia_common.quotation_subjectVision DisordersVisual AcuityNerve fibre layerGrey substanceContrast SensitivityCellular and Molecular Neurosciencechemistry.chemical_compoundMultiple Sclerosis Relapsing-RemittingOptical coherence tomographyOphthalmologymedicineContrast (vision)HumansMacula Luteamedia_commonmedicine.diagnostic_testbusiness.industryMultiple sclerosisRetinalAnatomymedicine.diseaseeye diseasesSensory SystemsAxon lossOphthalmologychemistryFemalesense organsbusinessThe British journal of ophthalmology
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Enhanced depth imaging optical coherence tomography of the choroid in idiopathic macular hole: A cross-sectional prospective study.

2010

Purpose To determine the choroidal thickness in the macular area in patients with idiopathic macular hole in one eye and an unaffected fellow eye and in healthy controls. Design Cross-sectional, prospective study. Methods Twenty-two patients with a full-thickness unilateral idiopathic macular hole and 22 age- and sex-matched controls were recruited. Enhanced depth imaging optical coherence tomography images were obtained by using spectral-domain optical coherence tomography. The choroidal thickness was measured in the subfoveal area and 1000 μm and 2000 μm away from the fovea in the nasal and temporal regions. The diameter of the macular hole and the axial length were determined. Results Ch…

Malemedicine.medical_specialtygenetic structuresEye diseaseOptical coherence tomographyOphthalmologymedicineHumansProspective StudiesProspective cohort studyMacular holeAgedCross-Sectional StudieAged 80 and overmedicine.diagnostic_testbusiness.industryChoroidMiddle Agedmedicine.diseaseRetinal Perforationseye diseasesProspective StudieOphthalmologyAxial Length Eyemedicine.anatomical_structureCross-Sectional StudiesRetinal PerforationMaculopathyFemalesense organsEnhanced depth imagingChoroidbusinessTomography Optical CoherenceHumanRetinopathyAmerican journal of ophthalmology
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Intravitreal Plasmin Without Associated Vitrectomy as a Treatment for Refractory Diabetic Macular Edema

2009

To determine the effectiveness of a low-dose intravitreal injection of autologous plasmin enzyme (APE), without the performance of a vitrectomy, as a treatment for refractory diffuse diabetic macular edema (DDME).Prospective, comparative, interventional case series.Sixteen patients with bilateral DDME who had not responded to prior laser photocoagulation. All patients received an injection in 1 eye, while the other eye served as a control.Intravitreal 0.2 mL APE injection under topical anesthesia. The APE was obtained using a simplified method.Central macular thickness (CMT) at 1 and 6 months, determined by optical coherence tomography (OCT) and best corrected visual acuity (BCVA).All patie…

Malemedicine.medical_specialtygenetic structuresPlasminmedicine.medical_treatmentEye diseaseVisual AcuityVitrectomyMacular EdemaInjectionsFibrinolytic AgentsOptical coherence tomographyRefractoryDiabetes mellitusOphthalmologyHumansMedicinePharmacology (medical)FibrinolysinProspective StudiesProspective cohort studyAgedPharmacologyDiabetic RetinopathyLaser Coagulationmedicine.diagnostic_testbusiness.industryMiddle Agedmedicine.diseaseeye diseasesVitreous BodyOphthalmologyFemalesense organsbusinessTomography Optical CoherenceFollow-Up StudiesRetinopathymedicine.drugJournal of Ocular Pharmacology and Therapeutics
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Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population

2018

PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects. METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity. RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.…

Malemedicine.medical_specialtygenetic structuresPopulationNormal valuesCornea03 medical and health sciences0302 clinical medicineScleral lenshemic and lymphatic diseasesCorneaOphthalmologyHumansMedicineProspective Studieseducationeducation.field_of_studybusiness.industryOsmolar ConcentrationfungiBoth lensesEquipment DesignPresbyopiaGeneral MedicinePresbyopiaMiddle AgedContact Lenses Hydrophilicmedicine.diseaseeye diseasesOphthalmologymedicine.anatomical_structureTear meniscusTears030221 ophthalmology & optometryOptometryFemalesense organsbusinessOcular surfaceScleraTomography Optical Coherence030217 neurology & neurosurgeryFollow-Up StudiesOptometryContact Lens and Anterior Eye
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