Search results for "Collage"
showing 8 items of 638 documents
Enhanced prolylhydroxylase activity in the posterior annulus fibrosus of canine intervertebral discs following long-term running exercise
2010
The effect of long-term excercise on the intervertebral disc collagen concentration (hydroxyproline), collagen-synthesizing enzymes (prolyl-4-hydroxylase, PH, and galactosyl-hydroxylysyl glucosyltransferase, GGT) and hydroxypyridinium crosslinks was studied in ten female beagle dogs. The dogs were run on a treadmill for 1 year starting at the age of 15 weeks. The daily running distance was gradually increased to 40km, which distance the dogs ran for the final 15 weeks. Ten untrained dogs from the same breeding colony served as controls. The nucleus pulposus and anterior and posterior halves of the annulus fibrosus of C2-3, T10-12, L4-5 disc segments were analysed. Crosslinks were measured f…
Extracellular matrix regulation of PTHrP and PTH/PTHrP receptor in a human breast cancer cell line
1999
AbstractIt was previously reported that 8701-BC breast cancer cells express the gene for parathyroid hormone-related peptide (PTHrP) and its cognate receptor (PTHrP-R), and release immunoreactive PTHrP in the extracellular medium; it was also found that PTHrP, in turn, exerts a role on the proliferative and invasive behavior in vitro of the same cell line. On the other hand, evidence has been produced that adhesion of 8701-BC cells onto different collagen substrates influences in various ways a number of phenotypic expressions, such as cell growth, motility, invasion of reconstituted basement membrane and production of lytic enzymes of the extracellular matrix (ECM). In light of these previ…
Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis.
2008
Contains fulltext : 70589.pdf (Publisher’s version ) (Closed access) OBJECTIVE: CO-releasing molecules (CO-RMs) are a novel class of anti-inflammatory agents. We have examined the possible therapeutic effects of CORM-3 in collagen-induced arthritis (CIA). METHODS: Arthritis was induced in DBA-1/J mice by type II collagen. Animals were treated with CORM-3 (5 and 10 mg/kg/day, intraperitoneally) or the inactive compound iCORM-3 (10 mg/kg/day, intraperitoneally) unable to release CO, from days 22 to 31. Production of anti-type II collagen antibodies, cytokines and cartilage olimeric matrix protein (COMP) was evaluated by enzyme-linked immunosorbent assay, and prostaglandin E(2) (PGE(2)) by rad…
Blocks to, and building blocks of, narrativity : fragments, anecdotes, and narrative lines in David Markson’s Reader’s block
2017
David Markson’s Reader’s block (1996) consists of 193 pages of quotations, anecdotes, names, and fragments. The book bears the paratext “A novel,” and the work has indeed been read as a narrative whole, in which “an aging author [...] contemplates the writing of a novel.” By being out of ordinary and therefore worth of telling, the anecdotes or curiosities seemingly fulfill the requirements of a “natural” narrative as defined by Monika Fludernik (1996). However, a mass of such mini-narratives, mixed with even more fragmentary texts, seems to defy narrativity (and tellability). In my reading, the ostensive block to narrativity also functions as its very building block. Thanks to polysemy, bl…
Analisi quantitativa del tessuto tendineo di ratto adulto allenato
2011
Kolāžu izmantošana vārdu krājuma nostiprināšanai angļu valodas stundās 3. klasē
2015
Diplomdarba mērķis bija atrast veidu, kā nostiprināt vārdu krājumu svešvalodā 3. klasē, pārvēršot to par aktīvu vārdu krājumu, izmantojot kolāžas. Darba tēma tika izvēlēta, jo autore tic, ka vārdu krājums ir pamats svešvalodu apgūšanā. Skolotāja uzdevums ir palīdzēt skolēniem apgūt vārdu krājumu, izmantojot vizuālos materiālus mācību procesā pēc iespējas vairāk. Izvēlētā pētījuma metode bija atsevišķa gadījuma pētījums, kas tika veikts Rīgas 32. vidusskolā 3. klasē. Datu vākšanas metodes bija 2 testi skolēniem, intervija ar vietējo angļu valodas skolotāju un skolēnu anketa. Pētījums pierādīja to, ka skolēni izbaudīja laiku veidojot kolāžas, turklāt skolēni nostiprināja vārdu krājumu angļu v…
An arthritogenic alphavirus uses the α1β1 integrin collagen receptor
2005
Ross River (RR) virus is an alphavirus endemic to Australia and New Guinea and is the aetiological agent of epidemic polyarthritis or RR virus disease. Here we provide evidence that RR virus uses the collagen-binding alpha1beta1 integrin as a cellular receptor. Infection could be inhibited by collagen IV and antibodies specific for the beta1 and alpha1 integrin proteins, and fibroblasts from alpha1-integrin-/- mice were less efficiently infected than wild-type fibroblasts. Soluble alpha1beta1 integrin bound immobilized RR virus, and peptides representing the alpha1beta1 integrin binding-site on collagen IV inhibited virus binding to cells. We speculate that two highly conserved regions with…