Search results for "Colon"
showing 10 items of 2038 documents
Autophagy and ER-stress participate to cannabinoid-induced apoptosis in colon carcinoma cells
2012
In vitro antitumor effects of the cold-water extracts of Pleurotus eryngii var ferulae and Pleurotus nebrodensis on human colon cancer cells
2013
For centuries, mushrooms have been used as folk medicines especially in Asian countries where their medicinal properties are well known. On the basis of numerous experimental evidences collected in the last decades, the immunomodulatory and anti-neoplastic properties of substances extracted from various species belonging to genera of edible mushrooms [Agaricus L., Auricularia Bull. ex Juss., Ganoderma P. Karst., Grifola Gray, Lentinus Fr., Schizophyllum Fr., Tremella Dill ex L., etc.] are extensively recognized also at scientific levels. Several works have demonstrate that anti-cancer property of these molecules is due to their ability to enhance immune system activity and/or to act directl…
Wharton’s Jelly Mesenchymal Stromal Cells Support the Expansion of Cord Blood–derived CD34+Cells Mimicking a Hematopoietic Niche in a Direct Cell–cel…
2018
Wharton’s jelly mesenchymal stromal cells (WJ-MSCs) have been recently exploited as a feeder layer in coculture systems to expand umbilical cord blood–hematopoietic stem/progenitor cells (UCB-HSPCs). Here, we investigated the role of WJ-MSCs in supporting ex vivo UCB-HSPC expansion either when cultured in direct contact (DC) with WJ-MSCs or separated by a transwell system or in the presence of WJ-MSC–conditioned medium. We found, in short-term culture, a greater degree of expansion of UCB-CD34+cells in a DC system (15.7 ± 4.1-fold increase) with respect to the other conditions. Moreover, in DC, we evidenced two different CD34+cell populations (one floating and one adherent to WJ-MSCs) with …
Immunohistochemical and molecular expression of CB1 receptors in human colonic segment. Preliminary results
2011
Recent studies document that CB1 cannabinoid receptors, considered since its first identification as “brain specific”, could be expressed by peripheral tissues targets (adipose organs, enteric nervous system, striated muscle, epatocytes). This receptors were found in the GI tract of different species, including mice, rats, guinea pigs, pigs and humans. Endocannabinoids play a role in the pathophysiology of the gastrointestinal tract. They play a role in emesis, acid-related disorders, motility-related disorders, irritable bowel syndrome and diarrhea, and in inflammatory bowel disease. Endocannabinoid system might be involved in cancer differentiation, growth and cell migration. Distribution…
Ciprofloxacin Polymers Derived from Diallyltin and Divinyltin Dihalides
2008
The initial synthesis of condensation polymers from newly available divinyltin dichloride and diallyltin dichloride and ciprofloxacin is accomplished employing a modified interfacial polycondensation process. The polymeric (DP are about 2,000) products are rapidly (less than 15 seconds) formed in good yield. Infrared spectroscopy shows the formation of Sn-O and Sn-N bonds as predicted from the proposed structure. F-MALDI MS also shows ion fragments containing organotin in the predicted isotopic abundances as well as ion fragments containing both organotin and ciprofloxacin. The polymers exhibit low toxicity towards healthy WI-38 cells with variable toxicities towards a variety of cancer cel…
Nuovi Sistemi Polimerici a base di Polisaccaridi/Poliamminoacidici per il Rilascio Colon Specifico Di Farmaci
2008
Sostenibilità di interventi di miglioramento sismico di strutture in c.a. non danneggiate
2012
INFLUENZA DEL DIAMETRO DEL FORO SUL COMPORTAMENTO IN COMPRESSIONE DI COLONNE IN C.A.
2012
Core-drilling technique is nowadays always more frequently performed in existing reinforced concrete (RC) structures in order to investigate on the mechanical properties of concrete and for structural health monitoring purposes. Even if the engineering practice discourages to drill columns, this can be often unavoidable. In this last case the presence of the circular opening influences the compressive behavior of the column in terms of load-carrying capacity and axial deformability. The goal of this investigation was the experimental evaluation of the effects induced by circular openings on the behavior of RC columns. 24 reinforced and plain concrete prisms in presence of circular openings …
Progetto ed analisi del comportamento di nodi esterni in calcestruzzo fibrorinforzato
2010
ANALISI SPERIMENTALE DEL COMPORTAMENTO CICLICO DI NODI DI TRAVI SER E PILASTRI IN C.A.
2012
Results of experimental investigation on cyclic behavior of beam-column joints made up of hybrid steel trussed concrete beams connected to reinforced concrete columns are presented. Specimens are representative of joints in framed structures subjected to seismic actions designed according to current Italian technical standard codes. The aim of the experimental testing was to verify strength capacity and ductility of the connection, focusing both the global behavior and the force transmission mechanisms between steel truss and concrete in the region close to the beam-column joint.