Search results for "Colon"
showing 10 items of 2038 documents
Bafouoside C, a new triterpenoid saponin from the roots of Cussonia bancoensis Aubrev. & Pellegr.
2014
Abstract A new triterpenoid saponin named bafouoside C 3-O-β- d -glucopyranosyl-(1 → 4)-[β- d -galactopyranosyl-(1 → 2)]-β- d -glucuronopyranosyloleanolic acid 28-O-β- d -glucopyranosyl ester; (1), together with five known compounds 3-O-β- d -galactopyranosyl-(1 → 2)-β- d -glucuronopyranosyloleanolic acid (2), 23-hydroxyursolic acid (3), 28-O-α- l -rhamnopyranosyl-(1 → 4)-O-β- d -glucopyranosyl-(1 → 6)-O-β- d -glucopyranosyl-23-hydroxyursolic acid (4), 3-O-β- d -glucopyranosyl-23-hydroxyursolic acid (5), and 3-O-α- l -arabinopyranosyl-23-hydroxyursolic acid (6), were isolated from the roots of Cussonia bancoensis Aubrev. & Pellegr. Their structures were established on the basis of 1D- and 2…
Structure elucidation of new oleanane-type glycosides from three species of Acanthophyllum
2010
From the roots of three species of Acanthophyllum (Caryophyllaceae), two new gypsogenic acid glycosides, 1 and 2, were isolated, 1 from A. sordidum and A. lilacinum, 2 from A. elatius and A. lilacinum, together with three known saponins, glandulosides B and C, and SAPO50. The structures of 1 and 2 were established mainly by 2D NMR techniques as 23-O-β-D-galactopyranosylgypsogenic acid-28-O-β-D-glucopyranosyl-(13)-[β-D-glucopyranosyl-(16)]-β-D-galactopyranoside (1) and gypsogenic acid-28-O-β-D-glucopyranosyl-(13)-[β-D-glucopyranosyl-(16)]-β-D-galactopyranoside (2). The cytotoxicity of several of these saponins was evaluated against two human colon cancer cell lines (HT-29 and HCT 116). Copyr…
Chiese colonnari in Sicilia (XVI secolo)
2009
Nei primi decenni del Cinquecento la gara tra le confraternite mariane di Palermo riportò nel dibattito architettonico il tema della chiesa impostata su colonne. Il mito normanno e le contemporanee ricerche del Nord Italia furono sintetizzate per realizzare edifici moderni e suggestivi. In breve tempo la vicenda innescò la costruzione di una serie di nuove fabbriche colonnari nell'intera isola: Santa Maria di Portosalvo, Santa Maria della Catena, Santa Maria la Nova,Santa Maria del Gesù a Trapani,la chiesa madre di Caltabellotta e il San Francesco a Tortorici.
Phenazine antibiotics produced by fluorescent pseudomonads contribute to natural soil suppressiveness to Fusarium wilt
2009
Natural disease-suppressive soils provide an untapped resource for the discovery of novel beneficial microorganisms and traits. For most suppressive soils, however, the consortia of microorganisms and mechanisms involved in pathogen control are unknown. To date, soil suppressiveness to Fusarium wilt disease has been ascribed to carbon and iron competition between pathogenic Fusarium oxysporum and resident non-pathogenic F. oxysporum and fluorescent pseudomonads. In this study, the role of bacterial antibiosis in Fusarium wilt suppressiveness was assessed by comparing the densities, diversity and activity of fluorescent Pseudomonas species producing 2,4-diacetylphloroglucinol (DAPG) (phlD+) …
A multi-omic liquid biopsy-based signature as a valuable tool to assess minimal residual disease in localised colorectal cancer
2019
El cáncer colorrectal (CCR) es un importante problema de salud pública. Más de 1.2 millones de pacientes se diagnostican de CCR cada año, y más de 600.000 mueren a causa de la enfermedad. El pronóstico de los pacientes con CCR ha mejorado durante las últimas décadas, con una supervivencia a los 5 años que ha alcanzado casi el 65% en países desarrollados. El estadio al diagnóstico es actualmente el factor pronóstico más importante. Aunque la clasificación clásica de estadiaje proporciona información pronóstica y guía las decisiones terapéuticas, no disponemos hoy en día de marcadores predictivos de la respuesta y del resultado clínico de la terapia individual del paciente. Esto es relevante …
Le combat de Victor Schoelcher contre la légalité de l'esclavage : l'abolition de 1848
2009
How has the French State been able to maintain slavery for more than fifty years after the Déclaration des droits de l'homme et du citoyen of 1789? The slave was considered, in a legal scope, not as a person but as a « movable », he was considered as an object that could be bought, sold, mutilated and tortured! Abolished for the first time in 1794, reinstated in 1802 by Napoleon Bonaparte, slavery would definitively disappear in France only in 1848, thanks to Victor Schoelcher's (1804-1893) decisive action. This great humanist, by a tireless fight, managed to impose an immediate abolition – and not a progressive one as in Britain – showing that if this institution was certainly legal, it wa…
Victor Schoelcher, abolitionniste et républicain : approche juridique et politique de l'oeuvre d'un fondateur de la République
2000
The aim of this judicial and political analysis is to reveal Victor Schoelcher's decisive influence in the fight for equal rights and for the republic, in the French mainland as well as in its colonies. His well known fight against slavery was just a part of his humanist defense of the republican principles : Liberty, Equality, Fraternity. Schoelcher truly was a founder of the republic, taking part in the barricade insurrections against the 1851 coup and fighting against any kind of slavery or absolutism. His work addressed many aspects of our society, among which : - Slavery and the colonies (legal status of slaves, emancipated slaves and of the colonies) - Rights and liberties of men and …
Role for D1-like and D2-like dopamine receptors in the modulation of intestinal motility in mice
2015
Objective: In the last years a plethora of studies addressed dopamine (DA) as a modulator within the enteric nervous system (ENS), controlling gastrointestinal (GI) functions via activation of D1- and D2-like receptors. However, the effective role and functional significance of DA in the ENS, and the contribution of its receptors, are still a matter of debate. Pathological alterations of dopaminergic system in the gut may be likely implicated in different motor GI disorders, including dyspepsia and gastroparesis. Thus, a detailed characterization of the enteric dopaminergic signalling is necessary. The aim of this study was to explore the role of DA in the GI tract, using as model the mouse…