Search results for "Color"

EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells.

2015

KRAS mutational status is considered a negative predictive marker of the response to anti-EGFR therapies in colorectal cancer (CRC) patients. However, conflicting data exist regarding the variable response to EGFR-targeted therapy. The effects of oncogenic KRAS on downstream targets were studied in cell lines with different KRAS mutations. Cells harboring a single KRASG13D allele showed the most tumorigenic profile, with constitutive activation of the downstream pathway, rendering them EGF-unresponsive. Conversely, KRASA146T cells showed a full EGF-response in terms of signal transduction pathways, cell proliferation, migration or adhesion. Moreover, the global acetylome of CRC cells was al…

Method for Reproducible Shipboard Segmented Flow Analysis Ammonium Measurement Using an In-House Reference Material for Quality Control

2021

Ammonium is a fundamental nutrient for phytoplankton growth in seawater and is a key component of the microbial loop. Ammonium measured in parallel with other nutrients is crucial in understanding the small temporal scale changes in oceanographic ecology. Despite the importance of measuring ammonium at sea, owing to its lability, there is no consensus on the best method. The lack of availability of certified reference materials for ammonium in seawater also makes it difficult to assess the accuracy and reproducibility of ammonium measurements. In this study we present a modified segmented flow analysis method using ortho-phthaldialdehyde (OPA) with fluorescence detection to measure ammonium…

Las tecnologías de la información y comunicación como herramienta de análisis, evaluación y clasificación de heridas crónicas y neoplásicas. Una revi…

2019

RESUMEN: Objetivo: Analizar el tipo de información aportada por las diferentes tecnologías de la información y comunicación (TIC) disponibles para el análisis, gestión o evaluación de heridas crónicas y lesiones de origen neoplásico, así como su impacto en los cuidados de las mismas, en términos de valoración y resolución de las lesiones. Metodología: Se realizó una revisión sistemática usando las recomendaciones de la Cochrane Collaboration. Se utilizaron las bases de datos MEDLINE (a través de PubMed), Web Of Science y SCOPUS. La estrategia de búsqueda para …

Multispectral analysis of color vision deficiency tests

2011

Color deficiency tests are usually produced by means of polygraphy technologies and help to diagnose the type and severity of the color deficiencies. Due to different factors, as lighting conditions or age of the test, standard characteristics of these tests fail, thus not allowing diagnosing unambiguously the degree of different color deficiency. Multispectral camera was used to acquire the spectral images of the Ishihara and Rabkin pseudoisochromatic plates in the visible spectrum. Spectral data was converted to cone signals, and successive mathematics applied to provide a simple simulation of the test performance. Colorimetric data of the each pixel of the test image can be calculated an…

Rayleigh Equation Anomaloscope from Commercially Available LEDs

2012

Most precise classification of CVD (color vision deficits) can be provided by using anomaloscope. Today anomaloscopes are available, which can evaluate red-green (Rayleigh) and blue-green (Moreland) color defects.DOI: http://dx.doi.org/10.5755/j01.ms.18.2.1928

From arsenic to DDT: Pesticides, Fascism and the invisibility of toxic risks in the early years of Francoist Spain (1939-1953)

2021

This paper reviews the way in which Spanish agriculture climbed onto the pesticide treadmill. We claim that Fascist policies and expert advice assembled in the early 1940s accelerated the introduction of pesticides into Spanish agriculture and promoted the emergence of the Spanish pesticide industry in the times of autarky. Agricultural engineers were the key protagonists in this process, but other human and non-human actors also played a pivotal role: a new pest (the Colorado beetle), Francoist politicians, farmers, landowners and industry managers. Our focus is on the use of pesticides against the Colorado beetle (the main threat to the potato crop), and the transition from arsenical pest…

Co-evolution between streaming and live music leads a way to the sustainable growth of music industry : Lessons from the US experiences

2017

While digitization of music, particularly streaming services, has gained increasing popularity, it has also led to a steady decline in the revenues of recorded music industry. This is causing strong concern regarding a potential collapse of the music industry comparable to other print media industries such as newspaper and book publishing. However, recent changes in the music industry initiated by a resurgence of the live music industry are giving rise to some expectations for the survival and growth of the music industry. The parallel paths of increasing popularity of streaming services and a resurgence of live music suggest that these two dynamics are working together in a co-evolutionary…

La luz y el color en la arquitectura contemporánea: los nuevos escenarios urbanos

2010

"Cuando a finales del siglo XIX, Claude Monet pintó la catedral de Rouen, vista en diferentes horas del día, desde el amanecer al atardecer, nos da una demostración de cómo un solo monumento podría tener configuraciones y aspectos diferentes debido exclusivamente a la capacidad de la luz de modelar formas. Pero también nos da otra lección: de cuanto sea importante en la fruición de un lugar la posibilidad de leer el paso del tiempo a través de la alteración de la percepción debida a la evolución de las formas y los colores, específicamente en relación con el cambio de luz "[1]. La investigación se propone una reinterpretación del paisaje urbano, considerando el proyecto luz como elemento in…

Il Grigio di Billiemi

2009

Possible role of differential metalloproteinase 1 expression in signet ring cell and intestinal colorectal carcinoma histotypes

2008

Background: Pure signet ring cell colorectal carcinoma ( SRCC) is an infrequent and highly malignant histological variant of colorectal cancer (CRC), while it is present as a histological component in colorectal carcinomas more frequently. Materials and Methods: The aim of this was to widen the knowledge of the biological factors involved in the pathogenesis and aggressiveness of SRCC by the identification and evaluation of possible molecular abnormalities. By means of immunohistochemistry the expression of the proteolytic degradation enzyme matrix metalloprotease (MMP)-1, that is a collagenase specifically degrading collagens I, II, III and of the adhesion proteins E-cadherin, B-catenin an…