Search results for "Coma"

Oxygenation Status of Rhabdomyosarcoma Spheroids with Different Stages of Differentiation

1994

Multicellular tumor spheroids with regional heterogeneities of proliferation and substrate concentrations have been investigated recently to study the biological properties of small tumor nodules prior to onset of vascularization (for reviews see: Mueller-Klieser, 1987; Sutherland, 1988).

A pilot study on the differences in wavefront aberrations between two ethnic groups of young generally myopic subjects

2008

A comparative population-based cross-sectional study design was used to examine the prevalence of wavefront patterns in two different ethnic groups, and the relationship of these patterns with ocular biometrics and gender. The Shin–Nippon SRW5000 open field autorefractor, the Wavefront Analysis Supported Customized Ablation (WASCA) wavefront analyser and the IOLMaster were used to determine wavefront aberrations, mean spherical equivalent (SE) refractive error and axial length (AL). Seventy-four eyes from 74 young healthy subjects (44 British Asians, 30 Caucasians; 36 men, 38 women; mean age 22.51 ± 3.89 years) with mean SE averaging )1.90 ± 2.76 D (range )10.88 to +2.19 D) were examined. R…

Plasmalogens in the pathogenesis of glaucomatous optic neuropathy

2011

Neuronal tissues such as the retina contain high amounts of plasmalogens. One of their particularities is to concentrate polyunsaturated fatty acids (PUFA) before releasing them specifically. Several data from our laboratory suggest that plasmalogens are involved in the pathophysiology of primary open angle glaucoma (POAG), the second leading cause of blindness worldwide. The different experiments were carried out on human patients with POAG as well as on rodent models of glaucoma. They concerned either the identification of specific alterations of plasmalogen metabolism, or the efficacy of PUFAs to prevent retinal damage. The results have shown a loss of several circulating plasmalogens in…

Cholesterol metabolism via cyp46a1 in glaucoma

2012

Cholesterol metabolism via cyp46a1 in glaucoma. International society for eye research (ISER) annual meeting

Characterization of cholesterol metabolism in an experimental model of glaucoma in rats

2019

International audience; Glaucoma is a neurodegenerative pathology characterized by retinal ganglion cell death. Cholesterol homeostasis disruption has been implicated in several neurodegenerative diseases such as Alzheimer and Huntington. However, its specific role in the retina and association with glaucoma remain unclear. The aim of this study was to characterize the modifications of cholesterol metabolism occurring during an experimental model of glaucoma in rats. Eight-weeks old male rats were subjected to laser photocoagulation of episcleral veins, limbus and trabecular meshwork to elevate intraocular pressure. At a short (3 days) and a long (2 months) time period post-laser, the retin…

Patient/physician "Bond" in the management of glaucoma

2011

Patient/physician "Bond" in the management of glaucoma. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)

Cholestérol-24S-hydroxylase (CYP46A1) et homéostasie du cholestérol dans la rétine en conditions physiologiques et pathologiques

2012

Cholesterol is the major sterol found in the retina. In its free form, cholesterol is present in all cell layers of the retina, whereas cholesteryl esters mainly accumulate at the basement of the retinal pigment epithelium. The intrinsic capacity of the retina to synthetize cholesterol appears limited. Some extra-retinal pathways actively participate to cholesterol uptake to the retina. Müller glial cells may contribute to cholesterol supply to retinal neurons, especially for synaptic formation. Cholesterol accumulation or conversely deficiency have deleterious consequences on neuron survival. Maintaining the equilibrium between cholesterol supply and neosynthesis in the one hand and choles…

Populations bactériennes associées aux racines mycorhizées de Medicago truncatula: de la communauté à la souche bactérienne

2007

Le début et la fin de la personnalité juridique

1997

El modelado familiar y el papel educativo de los padres en la etiología del consumo de alcohol en los adolescentes

1998

Javier Pons Diez (Xavier.Pons@uv.es) Se pretende determinar las relaciones existentes entre el consumo de bebidas alcohólicas por parte de los adolescentes y dos variables psicosociales: el Consumo alcohólico de los otros miembros del sistema familiar y las estrategias educativas paternas.