Search results for "Community"
showing 10 items of 2132 documents
The Active Human Gut Microbiota Differs from the Total Microbiota
2011
The human gut microbiota is considered one of the most fascinating reservoirs of microbial diversity hosting between 400 to 1000 bacterial species distributed among nine phyla with Firmicutes, Bacteroidetes and Actinobacteria representing around of the diversity. One of the most intriguing issues relates to understanding which microbial groups are active players in the maintenance of the microbiota homeostasis. Here, we describe the diversity of active microbial fractions compared with the whole community from raw human fecal samples. We studied four healthy volunteers by 16S rDNA gene pyrosequencing. The fractions were obtained by cell sorting based on bacterial RNA concentration. Bacteria…
Optimising experimental research in respiratory diseases: an ERS statement
2018
Experimental models are critical for the understanding of lung health and disease and are indispensable for drug development. However, the pathogenetic and clinical relevance of the models is often unclear. Further, the use of animals in biomedical research is controversial from an ethical perspective.The objective of this task force was to issue a statement with research recommendations about lung disease models by facilitating in-depth discussions between respiratory scientists, and to provide an overview of the literature on the available models. Focus was put on their specific benefits and limitations. This will result in more efficient use of resources and greater reduction in the numb…
Brief Report: Intestinal dysbiosis in ankylosing spondylitis
2015
Objective Ankylosing spondylitis (AS) is a common, highly heritable immune-mediated arthropathy that occurs in genetically susceptible individuals exposed to an unknown but likely ubiquitous environmental trigger. There is a close relationship between the gut and spondyloarthritis, as exemplified in patients with reactive arthritis, in whom a typically self-limiting arthropathy follows either a gastrointestinal or urogenital infection. Microbial involvement in AS has been suggested; however, no definitive link has been established. The aim of this study was to determine whether the gut in patients with AS carries a distinct microbial signature compared with that in the gut of healthy contro…
Data from: Functional responses of multi-taxa communities to disturbance and stress gradients in a restored floodplain
2015
1. Trait-based approaches can reveal the mechanisms through which disturbances or stress impact communities, allowing comparisons of the role of different mechanisms in shaping communities among taxonomic groups. Such information can lead to higher comparability, transferability and predictability of the outcome of restoration projects. However, multitaxa trait-based approaches were rarely used in the context of ecosystem restoration. 2. We investigated the responses to environmental gradients of seven taxa (vascular plants, staphylinid and carabid beetles, spiders, isopods, diplopods and earthworms) in a restored floodplain using a species traits approach. We assessed the impact of flood d…
Lessons from uncertainty on antifungal treatment in ICU
2017
We read with great interest the Editorial from Moghnieh et al. on the EMPIRICUS trial and antifungal use in intensive care unit (ICU) (1). Authors described nicely the trial and some background evidence on untargeted antifungal treatment in non-neutropenic critically ill patients in ICU (2,3). However, we believe that some points may be further clarified. First, it may be useful to cite the study from Knitsch et al. among those evaluating empiric antifungal treatment in ICU (4). Knitsch et al. enrolled 252 critically ill patients with localized/generalized intra-abdominal infection either of community or of nosocomial origin requiring emergency surgery.
The HCV Sicily Network: A web-based model for the management of HCV chronic liver diseases
2016
Epidemiological studies report that in Sicily reside about 30,000 citizens with a diagnosis of chronic hepatitis due to HCV. The availability of direct antiviral action (DAA) is a real therapeutic breakthrough, but the high cost of the therapeutic regimes limits their use and forced the National Health System to establish clinical priority for the treatment.The HCV Sicily Network is a web-based model of best medical practice, which was designed to improve the management and the treatment of HCV chronic hepatitis and cirrhosis. The network includes 41 centers and 84 gastroenterologists or infectivologists connected by a web platform that recorder the diagnosis and the clinic priority for the…
The dual nature of mobile games: between escapism and finding a community
2021
Maģistra darbā tiek apskatīta mobilo spēļu duālā daba starp eskeipismu un komūnu (alianse S), kas tiek bāzēta BTK. Šī pētījuma ietvaros tiek skatīts kā komūna un eskeipisms sadzīvo, pastiprina un vai atrodas pretrunā viens ar otru. Galvenās izmantotās datu ievākšanas metodes ir daļēji atvērtā aptauja, daļēji strukturētas intervijas, dalība un novērojums, kā arī pētījums daļēji balstīts uz auto-etnogrāfiju. Pētījuma laikā tiek skatīts komūnas un eskeipisma koncepts un ietekme uz spēlētājiem, tostarp tiek skatīta arī pavadītā laika ietekme uz pieredzi, Covid-19 pandēmijas ietekmi un pētījumu veikšanu digitālajā vidē. Maģistra darbā tiek pamatots pieņēmums, ka mobilās spēles pašā būtībā nav ne…
La presencia del nietzscheanismo en la biopolítica contemporánea
2022
La filosofía de Nietzsche anticipó notablemente el umbral de la modernidad biológica al conceptualizar el alcance fisiológico de la moral, la política y la religión, así como su instrumentalización con fines de control social. El objetivo de este artículo es analizar el estímulo que ha representado la filosofía de Nietzsche para algunos de los principales pensadores de la cuestión biopolítica, en concreto, Michel Foucault, Roberto Esposito y Peter Sloterdijk, y desvelar en qué medida sus núcleos conceptuales convergen y divergen. La aportación concreta reside en señalar algunos de los vínculos que articulan el tema de la disciplina y la cría (Zucht und Züchtung) con la configuración de la b…
Proyectos educativos multidisciplinares y ayuda a la comunidad
2019
This paper relates an experience carried out at a higher education setting, specifically involving 3rd-year students in the Early Childhood Education degree programme. In relation to this, the paper presents an educational model that takes into account the need to develop ethical and social competences and gives importance to interdisciplinary education in real contexts. To this aim, all the academic modules that form part of this degree programme devote 25% of their teaching time and evaluation to the development of an interdisciplinary project. This paper will describe one of these projects, entitled "Solve a real problem", the design of which is informed by service-learning and problem-b…
Combined effects of heatwaves and micropollutants on freshwater ecosystems: Towards an integrated assessment of extreme events in multiple stressors …
2022
Freshwater ecosystems are strongly influenced by weather extremes such as heatwaves, which are predicted to increase in frequency and magnitude in the future. In addition to these climate extremes, the freshwater realm is impacted by the exposure to various classes of chemicals emitted by anthropogenic activities. Currently, there is limited knowledge on how the combined exposure to heatwaves and chemicals affects the structure and functioning of freshwater ecosystems. Here, we review the available literature describing the single and combined effects of heatwaves and chemicals on different levels of biological organization, to obtain a holistic view of their potential interactive effects. …