Search results for "Comparative"

showing 10 items of 1371 documents

Personalized cancer medicine: from molecular diagnostics to targeted therapy with natural products.

2010

Personalized cancer medicine aims to develop individualized treatment options adapted to factors relevant for the prognosis of each patient. Molecular biomarkers are required to predict the likelihood of an individual tumor's responsiveness or of toxicity in normal organs and to advise optimized treatments with improved efficacy at reduced side effects for each cancer patient. In the present review, we present a concept, which takes advantage of methods of molecular diagnostics to identify predictive markers at the DNA, mRNA, and protein levels. Markers with prognostic value concerning treatment response and patient survival can then be used as targets to develop optimized drugs. We focus o…

Oncologymedicine.medical_specialtyPathologymedicine.medical_treatmentPharmaceutical ScienceDrug resistanceAnalytical ChemistryTargeted therapyCytogeneticsInternal medicineNeoplasmsDrug DiscoverymedicineBiomarkers TumorHumansEpidermal growth factor receptorATP Binding Cassette Transporter Subfamily B Member 1RNA MessengerPrecision MedicinePharmacologyChemotherapyBiological ProductsAlanineAntibiotics Antineoplasticbiologybusiness.industryOrganic ChemistryCancerGenetic VariationMolecular diagnosticsmedicine.diseaseErbB ReceptorsComplementary and alternative medicineDrug Resistance NeoplasmPharmacogenomicsbiology.proteinMolecular MedicinebusinessComparative genomic hybridizationPhytotherapyPlanta medica
researchProduct

Tactical Web Use in Bumpy Times—A Comparison of Conservative Parties’ Digital Presence

2021

Modern-day party politics happen on two grounds: the offline sphere and the online sphere. It is the primary understanding of this chapter that both spheres complement each other. We therefore focus our contribution on governing parties and help to close this gap between online and offline communication and organisation by asking: How do conservative, governing parties deploy social media over a number of successful election campaigns? We explore whether there are tactical patterns or tendencies of media presence between different party channels during campaign and normal times with a longitudinal approach. Second, we introduce a multi-modal comparative research design and deliver theoretic…

Online and offlineFocus (computing)PoliticsOnline presence managementbusiness.industryComparative researchPolitical scienceSocial mediaComplement (linguistics)Public relationscomputer.software_genrebusinesscomputer
researchProduct

Navigating high-choice European political information environments : a comparative analysis of news user profiles and political knowledge

2021

The transition from low- to high-choice media environments has had far-reaching implications for citizens’ media use and its relationship with political knowledge. However, there is still a lack of comparative research on how citizens combine the usage of different media and how that is related to political knowledge. To fill this void, we use a unique cross-national survey about the online and offline media use habits of more than 28,000 individuals in 17 European countries. Our aim is to (i) profile different types of news consumers and (ii) understand how each user profile is linked to political knowledge acquisition. Our results show that five user profiles – news minimalists, social m…

Online and offlinecrossSociology and Political Sciencenews repertoires050801 communication & media studiescross-nationalnews media usePoliticsSeekers0508 media and communications10240 Department of Communication and Media Research3312 Sociology and Political ScienceComparative researchMedia usePolitical science050602 political science & public administrationcomparative researchSocial media070 News media journalism & publishingpolitical knowledgeUser profileCommunication05 social sciencesPoliticsnationalAdvertisingKnowledge acquisition[SHS.SCIPO]Humanities and Social Sciences/Political science0506 political scienceddc:Mass communications3315 CommunicationThe international journal of press/politics
researchProduct

Is There a Need for a European Institutional Research?

2013

Recent changes in European higher education have accompanied a strong desire and need by national ministries to have comparable data across institutions and a growing recognition from campus leaders that effective planning and decision-making requires reliable institutional data and analyses. This has induced changes and restructuring of duties and roles of administration, administrative staff and academic staff. In North America, internal institutional data analysis is often referred to as institutional research. We examine the roles and functions of institutional research within North America and how the changes within European higher education have created a purpose for institutional res…

Organizational Behavior and Human Resource ManagementHigher educationbusiness.industryRestructuringCorporate governanceData managementPublic administrationEuropean studiesEducationInstitutional researchPolitical scienceta516Comparative educationbusinessInstitutional theoryTertiary Education and Management
researchProduct

Análise de divulgação de risco no Relatório Anual de Governança corporativa utilizando fuzzy-set qualitative comparative analysis

2016

ABSTRACT This paper explores the necessary and sufficient conditions of good Corporate Governance practices for high risk disclosure by firms in their Corporate Governance Annual Report. Additionally, we explore whether those recipes have changed during the financial crisis. With a sample of 271 Spanish listed companies, we applied fuzzy-set qualitative comparative analysis to a database of financial and non-financial data. We report that Board of Directors independence, size, level of activity and gender diversity, CEO duality, Audit Committee independence, being audited by the Big Four auditing firms and the presence of institutional investors are associated with high risk disclosure. The…

Organizational Behavior and Human Resource ManagementInformation Systems and ManagementStrategy and Managementcorporate governancegobierno corporativolcsh:BusinessManagement Science and Operations Researchanálise comparativa qualitativa usando conjuntos fuzzyindependent directorManagement of Technology and Innovation0502 economics and businessfuzzy-set qualitative comparative analysisBusiness and International ManagementComposición del Consejo de AdministraciónMarketingcomité de auditoríaComposição do Conselho de AdministraçãoBoard compositiongovernança corporativa05 social sciencesdivulgação de risco050201 accountingrisk disclosurediretor independenteIndustrial relationsdivulgación de riesgosBusiness Management and Accounting (miscellaneous)lcsh:HF5001-6182050203 business & management
researchProduct

The relative relationship between education and workplace task discretion: an international comparative perspective

2019

International audience; Through analyses of Programme for the International Assessment of Adult Competencies (PIAAC) data, the following study considers the direct and indirect association between education and workplace task discretion in 30 countries. By focusing on cross-national comparison, it considers the ways in which these findings are dependent on both the overall level and the range of task discretion across occupational sectors within a country. Theoretically, individual-agency and critical-institutional hypotheses are compared, two perspectives that provide divergent explanations for the indirect association between education and task discretion. The findings partially support b…

Organizational Behavior and Human Resource ManagementPublic Administrationmedia_common.quotation_subject[SHS.EDU]Humanities and Social Sciences/EducationeducationApplied psychologyParticipative decision-makingLiteracyTask (project management)0502 economics and businessinternational comparative researchAssociation (psychology)skillmedia_commoneducationContext effectTask discretion05 social sciences050301 educationDiscretionQuality of working lifeEducational attainmentThe Programme for the International Assessment of Adult Competencies (PIAAC)Psychology0503 education050203 business & management
researchProduct

The influence of leadership styles on the internationalisation of 'born-global' firms and traditionally global-expanding firms

2018

Leadership and internationalisation are both established areas of scientific research, yet their interplay remains insufficiently examined. The present study focuses on the former and aims to shed more light on the intersection of leadership and internationalisation. By utilising fsQCA, a qualitative comparative analysis, to a set of 437 active international firms, results suggest that under distinct conditions transactional as well as transformational leadership can lead to a high level of internationalisation for both traditional internationalising and so-called 'born-global' firms.

Organizational Behavior and Human Resource ManagementQualitative comparative analysis05 social sciencesEducationInternationalizationTransactional leadershipTransformational leadership0502 economics and businessLeadership style050211 marketingEconomic geographyBusinessBusiness and International Management050203 business & managementEuropean J. of International Management
researchProduct

Understanding economic inactivity and NEET status among young women in the UK and France

2021

International audience; This article examines the position of young women in the UK and France who are defined as not in education, employment or training (NEET) and economically inactive (EI). While the challenges facing the young unemployed are well documented, far less is known about economic inactivity and its propensity to impact to a much greater extent on the lives of young women. The UK and France share some similarities with regard to their NEET EI female populations, in terms of the relative size of the group and the barriers young women face, despite being exposed to very different types of policy intervention and welfare support. Drawing on quantitative evidence (via the Céreq) …

Organizational Behavior and Human Resource Managementyoung womencomparative analysisPublic Administration[SHS.EDU]Humanities and Social Sciences/Education05 social sciences1. No poverty050301 educationUnited Kingdom0506 political scienceEducation5. Gender equalityPolitical scienceeconomic inactivity8. Economic growth050602 political science & public administrationPosition (finance)Demographic economicsNEETFrance10. No inequality0503 education
researchProduct

Sekcijas "Globalizācijas ietekme uz valsts ekonomiku un biznesu" Ekonomikas un vadības fakultātē (28. janvāris, 2016): Referātu tēzes

2016

Organizational changeBusiness managementWork slaveseducationSports Leagues - developing countriescomparative analysiscorporate governancePensiju līdzekļu pārvaldīšanadecision making processemotional intelligenceknowledge workersQuality management systemprofile oriented marketing:SOCIAL SCIENCES::Business and economics [Research Subject Categories]customer loyalty programmesglobalization
researchProduct

Ingegneri militari nella Sicilia degli Asburgo: formazione, competenze e carriera di una figura professionale tra Cinque e Seicento

2015

During the Sixteenth century and the first half of the following one, Sicily played a key role in the strategy of defense of the Spanish Empire from the looming Turkish threat, being an island considered as a baluarte against the Turks. Yet despite this absolute centrality in the military policy of the Spanish monarchy, till now historical research has preferred to provide broader spectrum interpretations at the expense of in-depth studies on individual technicians or overall pictures about the figure of the military engineer. We will present a synoptic view attesting the time period of activity covered by each military technician working for the kingdom of Sicily, within a wider study conc…

Organizational chartTurkishmedia_common.quotation_subjectMediterraneanMilitary EngineerHapsburgMilitary policyEarly Modern AgeMonarchyBuilt HeritageModern ageSettore ICAR/18 - Storia Dell'ArchitetturaSicilyMilitary engineersmedia_commonEmpireFortificationslanguage.human_languageHapsburgsGeographyMilitary EngineerAbsolute (philosophy)languageComparative historical researchHumanitiesCartography
researchProduct