Search results for "Compatibility"
showing 10 items of 859 documents
Use of Super Paramagnetic Iron Oxide Nanoparticles as Drug Carriers in Brain and Ear: State of the Art and Challenges
2021
International audience; Drug delivery and distribution in the central nervous system (CNS) and the inner ear represent a challenge for the medical and scientific world, especially because of the blood–brain and the blood–perilymph barriers. Solutions are being studied to circumvent or to facilitate drug diffusion across these structures. Using superparamagnetic iron oxide nanoparticles (SPIONs), which can be coated to change their properties and ensure biocompatibility, represents a promising tool as a drug carrier. They can act as nanocarriers and can be driven with precision by magnetic forces. The aim of this study was to systematically review the use of SPIONs in the CNS and the inner e…
Revisited mixed-value method via symmetric BEM in the substructuring approach
2012
Abstract Within the Symmetric Boundary Element Method, the mixed-value analysis is re-formulated. This analysis method contemplates the subdivision of the body into substructures having interface kinematical and mechanical quantities. For each substructure an elasticity equation, connecting weighted displacements and tractions to nodal displacements and forces of the same interface boundary and to external action vector, is introduced. The assembly of the substructures is performed through both the strong and weak regularity conditions of the displacements and tractions. We obtain the solving equations where the compatibility and the equilibrium are guaranteed in the domain Ω for the use of…
A prototypal PCB board for the EMI characterization of SiC-based innovative switching devices
2020
In this paper, a preliminary PCB board for the electromagnetic interference (EMI) characterization of innovative silicon-carbide (SiC) based switching devices is presented. Packaging technological issues can determine hurdles in the high-frequency switching and high power regime where wide band gap semiconductors are intended today for Electric Vehicle (EV) applications. In particular, the parasitic inductances that emerge in such devices, must be assessed, by using e.g. EMI techniques. In this specific case, the EMI characterization is supposed to be carried out in a semi-anechoic chamber, available at the University of Palermo (UNIPA), to assess the electromagnetic disturbances according …
Novel nanocrystalline cores for EMI suppression in cables: characterization methodology and performance study
2021
El control de las interferencias electromagnéticas (EMI) en dispositivos electrónicos es un problema cada vez mayor al que se enfrentan los diseñadores para garantizar que los dispositivos cumplan con los requisitos de compatibilidad electromagnética (EMC) para operar simultáneamente sin inferir entre sí. Este hecho se debe a la tendencia hacia una mayor integración de componentes, la reducción del tamaño y grosor de las placas de circuito impreso (PCB) y la miniaturización de las carcasas de los dispositivos. Además, otros factores como el empleo de frecuencias de conmutación más altas en los convertidores de potencia y las velocidades de datos de comunicación en los circuitos digitales. C…
On Language Adequacy
2015
Abstract The paper concentrates on the problem of adequate reflection of fragments of reality via expressions of language and inter-subjective knowledge about these fragments, called here, in brief, language adequacy. This problem is formulated in several aspects, the most general one being: the compatibility of the language syntax with its bi-level semantics: intensional and extensional. In this paper, various aspects of language adequacy find their logical explication on the ground of the formal-logical theory of syntax T of any categorial language L generated by the so-called classical categorial grammar, and also on the ground of its extension to the bi-level, intensional and ex- tensio…
Solid-state compatibility of Ca:LaNbO4 with perovskite cathodes: Evidences from X-ray microspectroscopy
2022
The solid-state compatibility between calcium-doped lanthanum niobate and three perovskite cathode materials was investigated using two X-ray microbeam techniques, micro X-ray fluorescence and micro X-ray absorption spectroscopy. The cathode powders (lanthanum strontium ferrite, either cobalt or copper-doped, and lanthanum strontium cobaltite) in contact with the dense electrolyte pellet were annealed at 1150 degrees C for 12-144 h to simulate the effect of thermal stresses due to fabrication and long-term operation. As a result, several interdiffusion phenomena were then observed on the bilayer cross-sections: in particular, the chemical state and coordination environment of calcium, iron,…
Cation Diffusion and Segregation at the Interface between Samarium-Doped Ceria and LSCF or LSFCu Cathodes Investigated with X-ray Microspectroscopy
2017
The chemical compatibility between electrolytes and electrodes is an extremely important aspect governing the overall impedance of solid-oxide cells. Because these devices work at elevated temperatures, they are especially prone to cation interdiffusion between the cell components, possibly resulting in secondary insulating phases. In this work, we applied X-ray microspectroscopy to study the interface between a samarium-doped ceria (SDC) electrolyte and lanthanum ferrite cathodes (La0.4Sr0.6Fe0.8Cu0.2O3(LSFCu); La0.9Sr0.1Fe0.85Co0.15O3(LSCF)), at a submicrometric level. This technique allows to combine the information about the diffusion profiles of cations on the scale of several micromet…
Polylactic acid, a sustainable, biocompatible, transparent substrate material for Organ-On-Chip, and Microfluidic applications
2019
AbstractOrgan-on-chips are miniaturised devices aiming at replacing animal models for drug discovery, toxicology and studies of complex biological phenomena. The field of Organ-On-Chip has grown exponentially, and has led to the formation of companies providing commercial Organ-On-Chip devices. Yet, it may be surprising to learn that the majority of these commercial devices are made from Polydimethylsiloxane (PDMS), a silicone elastomer that is widely used in microfluidic prototyping, but which has been proven difficult to use in industrial settings and poses a number of challenges to experimentalists, including leaching of uncured oligomers and uncontrolled adsorption of small compounds. T…
Hydrogen peroxide sensors for cellular imaging based on horse radish peroxidase reconstituted on polymer-functionalized TiO2 nanorods
2011
We describe the reconstitution of apo-horse radish peroxidase (apo-HRP) onto TiO2 nanorods functionalized with a multifunctional polymer. After functionalization, the horse radish peroxidase (HRP) functionalized TiO2 nanorods were well dispersible in aqueous solution, catalytically active and biocompatible, and they could be used to quantify and image H2O2 which is a harmful secondary product of cellular metabolism. The shape, size and structure of TiO2 nanorods (anatase) were analyzed by transmission electron microscopy (TEM), high resolution TEM (HRTEM), electron diffraction (ED) and X-ray diffraction (XRD). The surface functionalization, HRP reconstitution and catalytic activity were con…
Langmuir-Blodgett films of biocompatible poly(HPMA)-block-poly(lauryl methacrylate) and poly(HPMA)-random-poly(lauryl methacrylate): influence of pol…
2010
Membranes based on functional biocompatible polymers can be regarded as a useful model system to study biological interactions, e.g. antibody-antigen interactions or protein polymer interactions. These model systems may give a better insight into these processes and may help to find suitable polymeric structures offering biocompatibility as well as reduced polymer protein interaction. In this respect, Langmuir-Blodgett (LB) layer formation at the air/water (A/W) interface is studied in respect to polymer architecture in this article. For this purpose, narrowly distributed N-(2-hydroxypropyl)-methacrylamide (HPMA) random and block copolymers have been prepared by the RAFT polymerization meth…