Search results for "Compensation"
showing 10 items of 407 documents
MYC dosage compensation is mediated by miRNA-transcription factor interactions in aneuploid cancer
2021
Summary We hypothesize that dosage compensation of critical genes arises from systems-level properties for cancer cells to withstand the negative effects of aneuploidy. We identified several candidate genes in cancer multiomics data and developed a biocomputational platform to construct a mathematical model of their interaction network with micro-RNAs and transcription factors, where the property of dosage compensation emerged for MYC and was dependent on the kinetic parameters of its feedback interactions with three micro-RNAs. These circuits were experimentally validated using a genetic tug-of-war technique to overexpress an exogenous MYC, leading to overexpression of the three microRNAs …
Compensation of the impact of low-cost manufacturing techniques in the design of E-plane multiport waveguide junctions
2016
In this work, a full-wave tool for the accurate analysis and design of compensated E-plane multiport junctions is proposed. The implemented tool is capable of evaluating the undesired effects related to the use of low-cost manufacturing techniques, which are mostly due to the introduction of rounded corners in the cross section of the rectangular waveguides of the device. The obtained results show that, although stringent mechanical effects are imposed, it is possible to compensate for the impact of the cited low-cost manufacturing techniques by redesigning the matching elements considered in the original device. Several new designs concerning a great variety of E-plane components (such as …
Between commodification and altruism: gender imbalance and attitudes towards organ donation. A representative survey of the German community
2008
The German transplant law (TGP) of 1997 only recognises organ donation if the donor agrees (‘extended consent’) and if done for altruistic reasons. Several alternatives will be discussed here, including incentives and passive agreement. Based upon a representative survey, the authors examined the attitudes of Germans towards several European models of organ donation and their attitude towards organ donation in general whilst living and after death. The acceptance of possible compensation systems was also explored. In Germany the majority do not favour compensation systems, but rather passive agreement. There is evidence of gender difference with respect to this attitude. Men tend to favour …
Stakeholders’ Attitudes about the Transplantations of the Mediterranean Seagrass Posidonia oceanica as a Habitat Restoration Measure after Anthropoge…
2021
Anthropogenic impacts on Posidonia oceanica meadows have led to a decline of this ecosystem throughout the Mediterranean. Transplantations have often been prescribed as a compensation measure to mitigate the impacts caused by coastal maritime works. Here a Q methodology approach was used to investigate the stakeholders’ attitudes in four case studies of P. oceanica transplants realized in Italian waters. Twenty-two respondents were asked to score 37 statements, and the resultant Q-sorting was analyzed via an inverse PCA using the KADE software. Four discourses, corresponding to the significant axes in the factorial analysis were identified: science and conservation (F1), oriented at a rigor…
Nullité de plein droit. La compensation provoquée est un paiement anormal prohibé en période suspecte
2008
International audience; (Com. 13 févr. 2007, pourvoi n° 05-13.526, arrêt n° 228 FS-P+B+R+I, Sté Alès béton c/ André ès-qual., Juris-Data, n° 2007-037368 ; D. 2007. AJ. 583, obs. A. Lienhard ; JCP 2007. I. 153, n° 6, obs. M. Cabrillac ; Gaz. Pal. 13-14 avr. 2007. 40, note Ph. Roussel Galle)
Analysis and Evaluation of Adaptive RSSI-based Ranging in Outdoor Wireless Sensor Networks
2019
Estimating inter-node distances based on received radio signal strength (RSSI) is the foundation of RSSI-based outdoor localization in wireless sensor networks (WSNs). However, the accuracy of RSSI-based ranging depends on environmental and weather conditions. Therefore, it is important that RSSI-based ranging adapts to prevailing conditions to improve its range and location accuracy. This paper analyzes and evaluates RSSI-based ranging and adaptive techniques in outdoor WSNs to improve the range quality. The findings highlight the effects of path loss exponent (PLE) estimation error and temperature change on RSSI-based ranging. Consequently, we analyze techniques for mitigating these detri…
Meeting the environmental challenge of port growth: A critical appraisal of the contingent valuation method and an application to Valencia Port, Spain
2012
In order to support effective policy-making, this research is aimed to emphasise the need of measuring the negative impact - or external costs - resulting from port growth. Considering the non-market nature of these external costs, a critical appraisal of the Contingent Valuation method is made paying special attention to the problem of hypothetical bias and the suitability of a willingness to accept (WTA) scenario for damage assessment. Finally, the results of a case study, conducted in Valencia (Spain), are presented with the intention of paving the way for future research in this specific context of port growth and negative externalities. In particular, results indicate that the average …
A Control Algorithm for Active/Passive Hydraulic Winches Used in Active Heave Compensation
2019
Abstract The most common active heave compensated offshore cranes have hydraulic winch systems. This paper investigates an active/passive hydraulic winch system with variable-displacement motors and variable-displacement pumps. The paper addresses the challenges when the active motors are set with a low displacement. The active motor displacement is shown to have significant impact on the dynamics of the closed loop hydraulic system. The classical control strategy for this type of system do not address these challenges and will in certain situations have significantly reduced performance. Therefor, a new control method is presented that utilize the variable displacement of the pumps and mot…
Compensation. Compte courant, Solde créditeur, Dette certaine au titre de l'engagement de caution de la banque (oui), Exigibilité (non), Connexité (o…
1996
International audience; (Com. 6 févr. 1996, Mme de Thore ès qual. c/ BNP, D. 1997.353, note D. Boccara)
Compensation. Créances connexes. Dette de TVA antérieure au jugement d'ouverture et crédit de TVA généré par des opérations postérieures. Connexité (…
1999
International audience; (Com. 19 janv. 1999, Mme Du Buit, ès qual. c/ Receveur principal des impôts de Palaiseau Nord)