Search results for "Complement"
showing 10 items of 2113 documents
The “Circolo Matematico di Palermo” and the First World War: The crisis of scientific internationalism: a view through the unedited correspondence of…
2021
Abstract In this work the situation of the “Circolo Matematico di Palermo” between 1914 and 1928 is analyzed. It will be observed that during this time the Circolo was among the few European scientific associations with German as well as French associates. During the 1930s, the nationalist politics of Fascism and above all the racial laws dealt a deadly blow to the Circolo as an international scientific association. We will use the rich correspondence in the Circolo's archives to shed some light on this. In particular, the correspondence between M. De Franchis and E. Landau and other recently found documents will figure prominently.
Historical Origins of the nine-point conic -- The Contribution of Eugenio Beltrami
2020
In this paper, we examine the evolution of a specific mathematical problem, i.e. the nine-point conic, a generalisation of the nine-point circle due to Steiner. We will follow this evolution from Steiner to the Neapolitan school (Trudi and Battaglini) and finally to the contribution of Beltrami that closed this journey, at least from a mathematical point of view (scholars of elementary geometry, in fact, will continue to resume the problem from the second half of the 19th to the beginning of the 20th century). We believe that such evolution may indicate the steady development of the mathematical methods from Euclidean metric to projective, and finally, with Beltrami, with the use of quadrat…
From the theory of “congeneric surd equations” to “Segre's bicomplex numbers”
2015
We will study the historical pathway of the emergence of Tessarines or Bicomplex numbers, from their origin as "imaginary" solutions of irrational equations, to their insertion in the context of study of the algebras of hypercomplex numbers.
Gene Expression and Epigenetic Signatures of Germ Cell-Derived Pluripotent Stem Cells and Embryonic Stem Cells
2012
Germ cell-derived Pluripotent Stem Cells (gPSCs) are pluripotent stem cells that originate from Spermatogonial Stem Cells (SSCs) of the testis. Several reports in the last few years have shown that it is possible to isolate and enrich the SSC population by different approaches and even reprogram these in vivo multipotent cells to gPSCs in vitro. As these cells could be an alternative to circumvent the ethical objections regarding the use of Embryonic Stem Cells (ESCs) for therapeutic approaches, these SSC-derived gPSCs were characterized in several studies comparatively to the gold standard of pluripotency, the ESCs. The results provide great promise that gPSCs can be of importance for pra…
Cytotoxicity of the bisphenolic honokiol from Magnolia officinalis against multiple drug-resistant tumor cells as determined by pharmacogenomics and …
2014
A main problem in oncology is the development of drug-resistance. Some plant-derived lignans are established in cancer therapy, e.g. the semisynthetic epipodophyllotoxins etoposide and teniposide. Their activity is, unfortunately, hampered by the ATP-binding cassette (ABC) efflux transporter, P-glycoprotein. Here, we investigated the bisphenolic honokiol derived from Magnolia officinalis. P-glycoprotein-overexpressing CEM/ADR5000 cells were not cross-resistant to honokiol, but MDA-MB-231 BRCP cells transfected with another ABC-transporter, BCRP, revealed 3-fold resistance. Further drug resistance mechanisms analyzed study was the tumor suppressor TP53 and the epidermal growth factor recepto…
Additive effects of enhanced ambient ultraviolet B radiation and increased temperature on immune function, growth and physiological condition of juve…
2009
Climate change models predict increased ultraviolet B (UVB) radiation levels due to stratospheric ozone depletion and global warming. In order to study the impact of these two environmental stressors acting simultaneously on the physiology of fish, Atlantic salmon parr were exposed, for 8 weeks in outdoor tanks, to different combinations of UVB radiation (depleted and enhanced) and temperature (standard rearing temperature of 14 °C or 19 °C). The immune function (plasma IgM, lysozyme activity and complement bacteriolytic activity), growth (body weight) and physiological condition (haematocrit and plasma protein concentration) of the fish were determined. Increased UVB level, regardless of w…
Sponge Bcl-2 homologous protein (BHP2-GC) confers distinct stress resistance to human HEK-293 cells
2001
It is established that sponges, the phylogenetically oldest still extant phylum of Metazoa, possess key molecules of the apoptotic pathways, that is members from the Bcl-2 family and a pro-apoptotic molecule with death domains. Here we report on transfection studies of human cells with a sponge gene, GCBHP2. Sponge tissue was exposed to heat shock and tributyltin, which caused an upregulation of gene expression of GCBHP2. The cDNA GCBHP2 was introduced into human HEK-293 cells and mouse NIH-3T3 cells; the stable transfection was confirmed by the identification of the transcripts, by Western blotting as well as by immunofluorescence using antibodies raised against the recombinant polypeptide…
Does the Spatial Weight Configuration Matter in the Determination of the Effects of Environmental Externalities on Housing Prices?
2012
This paper highlights, from both a theoretical and an empirical point of view, how the choice of neighborhood and spatial weight affects the direct and indirect effects of environmental housing attributes on house price in environmental hedonic models.An original empirical investigation is herein undertaken for the area of the lower Loire estuary (France), in order to illustrate and complement our theoretical analysis. The first thing it shows is that as the radius of the neighborhood increases, the spatial specification changes from the Spatial Durbin to the SLAG model, which could modify the MWTP of the environmental attribute and therefore affect welfare analysis. It shows also that the …
Steiner configurations ideals: Containment and colouring
2021
Given a homogeneous ideal I&sube
Pseudohyphal Regulation by the Transcription Factor Rfg1p in Candida albicans
2010
ABSTRACT The opportunistic human fungal pathogen Candida albicans is a major cause of nosocomial infections. One of the fundamental features of C. albicans pathogenesis is the yeast-to-hypha transition. Hypha formation is controlled positively by transcription factors such as Efg1p and Cph1p, which are required for hyphal growth, and negatively by Tup1p, Rfg1p, and Nrg1p. Previous work by our group has shown that modulating NRG1 gene expression, hence altering morphology, is intimately linked to the capacity of C. albicans to cause disease. To further dissect these virulence mechanisms, we employed the same strategy to analyze the role of Rfg1p in filamentation and virulence. Studies using …