Search results for "Complementarity"
showing 10 items of 89 documents
An iterative method for pricing American options under jump-diffusion models
2011
We propose an iterative method for pricing American options under jump-diffusion models. A finite difference discretization is performed on the partial integro-differential equation, and the American option pricing problem is formulated as a linear complementarity problem (LCP). Jump-diffusion models include an integral term, which causes the resulting system to be dense. We propose an iteration to solve the LCPs efficiently and prove its convergence. Numerical examples with Kou@?s and Merton@?s jump-diffusion models show that the resulting iteration converges rapidly.
Molecular, Biological and Structural Features of V
2018
Microtubules are important drug targets in tumor cells, owing to their role in supporting and determining the cell shape, organelle movement and cell division. The complementarity-determining regions (CDRs) of immunoglobulins have been reported to be a source of anti-tumor peptide sequences, independently of the original antibody specificity for a given antigen. We found that, the anti-Lewis B mAb light-chain CDR1 synthetic peptide Rb44, interacted with microtubules and induced depolymerization, with subsequent degradation of actin filaments, leading to depolarization of mitochondrial membrane-potential, increase of ROS, cell cycle arrest at G2/M, cleavage of caspase-9, caspase-3 and PARP, …
Maximal Flavour Violation: a Cabibbo mechanism for leptoquarks
2018
We propose a mechanism that allows for sizeable flavour violation in quark-lepton currents, while suppressing flavour changing neutral currents in quark-quark and lepton-lepton sectors. The mechanism is applied to the recently proposed 4321 renormalizable model, which can accommodate the current experimental anomalies in $B$-meson decays, both in charged and neutral currents, while remaining consistent with all other indirect flavour and electroweak precision measurements and direct searches at high-$p_T$. To support this claim, we present an exhaustive phenomenological survey of this fully calculable UV complete model and highlight the rich complementarity between indirect and direct searc…
Black hole entropy in loop quantum gravity
2012
4 pags., 2 figs. -- Loops 11: Non-Perturbative / Background Independent Quantum Gravity 23–28 May 2011, Madrid, Spain
On the observability of Bell's inequality violation in the two-atoms optical Stern-Gerlach model
2005
Using the optical Stern-Gerlach model, we have recently shown that the non-local correlations between the internal variables of two atoms that successively interact with the field of an ideal cavity in proximity of a nodal region are affected by the atomic translational dynamics. As a consequence, there can be some difficulties in observing violation of the Bell's inequality for the atomic internal variables. These difficulties persist even if the atoms travel an antinodal region, except when the spatial wave packets are exactly centered in an antinodal point.
Black hole state counting in loop quantum gravity: a number-theoretical approach
2008
4 pages, 1 figure.-- PACS nrs.: 04.70.Dy, 04.60.Pp.-- ArXiv pre-print available at: http://arxiv.org/abs/0802.4077
Black hole state degeneracy in Loop Quantum Gravity
2008
The combinatorial problem of counting the black hole quantum states within the Isolated Horizon framework in Loop Quantum Gravity is analyzed. A qualitative understanding of the origin of the band structure shown by the degeneracy spectrum, which is responsible for the black hole entropy quantization, is reached. Even when motivated by simple considerations, this picture allows to obtain analytical expressions for the most relevant quantities associated to this effect.
Human leucocyte antigen-A2 restricted and Mycobacterium tuberculosis 19-kDa antigen-specific CD8+ T-cell responses are oligoclonal and exhibit a T-ce…
2001
CD8+ T cells can be grouped into two different types of secretory T lymphocytes, based on the cytokine-secretion pattern upon antigen exposure: those with a T-cell cytotoxic type 1 response (Tc1), which secrete interferon-gamma (IFN-gamma), or those with a T-cell cytotoxic type 2 response, which secrete interleukin (IL)-4 and IL-10. We examined the CD8+ T-cell response directed against an immunodominant human leucocyte antigen (HLA)-A2-presented peptide derived from a 19-kDa Mycobacterium tuberculosis-associated antigen. T cells were examined by functional analysis and by T-cell receptor (TCR) complementarity-determining region 3 (CDR3)-spectratyping, which defines the complexity of a T-cel…
On the signaling effect of reward-based crowdfunding: (When) do later stage venture capitalists rely more on the crowd than their peers?
2021
Abstract Venture capitalists (VCs) make only a small number of investments and are more likely to invest in ventures where other VCs have invested previously. As such, valuable opportunities may be forgone if they are not funded by VCs in the first place. We demonstrate how crowdfunding (CF) can remedy this concern. Using a sample of new technology-based ventures, we reveal that ventures initially funded through reward-based CF can be even more likely than those initially backed by VCs in attracting follow-up funds from VCs. This happens when ventures originally funded via reward-based CF complement the certification they derive from CF with patents and a founding team with a track record o…
Selection of single-chain antibodies against the VP8* subunit of rotavirus VP4 outer capsid protein and their expression in Lactobacillus casei.
2004
ABSTRACTSingle-chain antibodies (scFv) recognizing the VP8* fraction of rotavirus outer capsid and blocking rotavirus infection in vitro were isolated by phage display. Vectors for the extracellular expression inLactobacillus caseiof one of the scFv were constructed.L. caseiwas able to secrete active scFv to the growth medium, showing the potential of probiotic bacteria to be engineered to express molecules suitable for in vivo antirotavirus therapies.