Search results for "Complete"
showing 10 items of 490 documents
Are There Essentially Incomplete Knowledge Representation Systems?
2001
A mathematical model of a knowledge representation system (KR-system) is proposed. Its prototype is the concept of an information system in the sense of Z. Pawlak; however, the model is, in fact, a substantial extension of the latter. In our model, attributes may form an arbitrary category, where morphisms represent built-in functional dependencies, and uncertainty of knowledge is treated in terms of category theory via monads. Several notions of simulation are also considered for such KR-systems. In this general setting, the semiphilosophical problem mentioned in the title, still open, is given a precise meaning.
Consistency Analysis of Genome-Scale Models of Bacterial Metabolism: A Metamodel Approach.
2015
Genome-scale metabolic models usually contain inconsistencies that manifest as blocked reactions and gap metabolites. With the purpose to detect recurrent inconsistencies in metabolic models, a large-scale analysis was performed using a previously published dataset of 130 genome-scale models. The results showed that a large number of reactions (~22%) are blocked in all the models where they are present. To unravel the nature of such inconsistencies a metamodel was construed by joining the 130 models in a single network. This metamodel was manually curated using the unconnected modules approach, and then, it was used as a reference network to perform a gap-filling on each individual genome-s…
Kinerja Sapi Bali Jantan yang diberikan pakan Rumput Gajah (Punnisetum purpureum) subtitusi fermentasi Jerami Padi
2018
The research was aimed to study Bali bulls fed with Pennisetum purpureum with fermented rice straws substitution in Manokwari Regency, West Papua was conducted experimentally with 12 Bali bulls that have average weight of 176.02±38.35 kg with 2 – 2,5 years old for 5 months duration. The study was designed using complete randomized design of nested pattern with 3 (three) treatments, 4 (four) replications and 4 (four) times weighing, with an assumption that Bali bulls are nested during weighing time. The results of this study showed that Penicetum purpureum substitution with fermented straws did not significant on Bali bulls body weight. The duration of fermented rice straws feeding that subs…
The Mutational Landscape of Acute Myeloid Leukaemia Predicts Responses and Outcomes in Elderly Patients from the PETHEMA-FLUGAZA Phase 3 Clinical Tri…
2021
This article belongs to the Collection The Biomarkers for the Diagnosis and Prognosis in Cancer.
THE MAXWELL–DIRAC EQUATIONS: ASYMPTOTIC COMPLETENESS AND THE INFRARED PROBLEM
1994
In this article we present an announcement of results concerning: a) A solution to the Cauchy problem for the M-D equations, namely global existence, for small initial data at t = 0, of solutions for the M-D equations. b) Arguments from which asymptotic completeness for the M-D equations follows. c) Cohomological interpretation of the results in the spirit of nonlinear representation theory and its connection to the infrared tail of the electron in M-D classical field theory. The full detailed results will be published elsewhere.
Correcting for Potential Barriers in Quantum Walk Search
2015
A randomly walking quantum particle searches in Grover's $\Theta(\sqrt{N})$ iterations for a marked vertex on the complete graph of $N$ vertices by repeatedly querying an oracle that flips the amplitude at the marked vertex, scattering by a "coin" flip, and hopping. Physically, however, potential energy barriers can hinder the hop and cause the search to fail, even when the amplitude of not hopping decreases with $N$. We correct for these errors by interpreting the quantum walk search as an amplitude amplification algorithm and modifying the phases applied by the coin flip and oracle such that the amplification recovers the $\Theta(\sqrt{N})$ runtime.
Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma
2021
PETHEMA/GEM Cooperative Group.
Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast canc…
2021
Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast cancer (TNBC). We compared the analytical concordance and reproducibility of four clinically relevant PD-L1 assays assessing immune cell (IC) score, tumor proportion score (TPS), and combined positive score (CPS) in TNBC. Primary TNBC resection specimens (n = 104) were stained for PD-L1 using VENTANA SP142, VENTANA SP263, DAKO 22C3, and DAKO 28–8. PD-L1 expression was scored according to guidelines on virtual whole slide images by four trained readers. The mean PD-L1 positivity at IC-score ≥1% and CPS ≥1 ranged between 53% and 75% with th…
Durability of complete response after blinatumomab therapy for relapsed/refractory diffuse large B-cell lymphoma
2020
Despite advances in standards of care, the prognosis of relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) remains poor. In these patients, 50–74% fail to respond to next line therapy,...
Durability of complete response after blinatumomab therapy for refractory/relapsed aggressive B-cell non-Hodgkin lymphoma.
2019
e19041 Background: Achieving durable response in patients (pts) with relapsed/refractory (R/R) aggressive B-cell lymphoma (B-NHL) is challenging. Blinatumomab, a bispecific T-cell engager (BiTE) immunotherapy targeting CD19-expressing cancer cells, has shown promising efficacy in pts with R/R aggressive B-NHL. We report the durability of complete response (DOCR) in pts treated with blinatumomab. Methods: The DOCR in pts with R/R aggressive B-NHL responding to blinatumomab was assessed using data from two phase 2 studies (study 1 [N = 25], NCT01741792; study 2 [N = 41], NCT02910063) in pts with R/R aggressive B-NHL. CR was assessed using Cheson (study 1) and Lugano (study 2) criteria. Time-…