Search results for "Complexity"
showing 10 items of 1094 documents
C1q secreted in the tumour microenvironment promotes tumour growth in the absence of complement activation
2012
We have recently shown that locally secreted C1q is involved in trophoblast invasion of decidua during pregnancy (Agostinis et al., J. Immunol. 2010;185;4420–4429). Since this physiologic process resembles to some extent tumor progression, we sought to investigate if C1q plays a similar role in tumor development and progression. Immunohistochemical analysis of several solid tumours including colon, prostate, lung and breast cancer and melanoma revealed the presence of C1q that was localized on the vascular endothelium and also distributed in the stroma in the absence of C4. To investigate the in vivo role of C1q in tumour development, 6/8 week old female WT and C1q−/− C57BL/6 mice received …
Exergoeconomic analysis as support in decision-making for the design and operation of multiple chiller systems in air conditioning applications
2020
Abstract Multiple-chillers systems represent viable solutions for medium/large-scale air conditioning applications characterized by variable cooling demand. The energy efficiency of such systems is influenced by the number of chillers, the combination of cooling capacities, and the load-sharing among the units. Large efforts have been devoted to developing efficient operation strategies for these systems, but rules of thumb are usually adopted for selecting cooling capacities thus leaving room for energy and economic savings. In this paper, exergoeconomic analysis is proposed as a promising method to identify near-optimal design and operation strategies, due to the capability of exergoecono…
Do too many choices have negative consequences? An empirical review
2013
Various experiments demonstrated that having too much choice has negative consequences on the motivation to choose and on the satisfaction with the chosen option. However, the literature reports conflicting results showing that choosing from large assortments has advantages. This paper reviews the main empirical results in favor and against the negative effect of too much choice and identifies possible directions for further research. Copyright © 2013 by Società editrice il Mulino.
Evaluation of several global resolution functions for liquid chromatography
1999
Abstract An interpretative approach, that makes use of the overlapped fraction of each chromatographic peak as elementary resolution criterion, was applied to the separation of mixtures of compounds. The elementary resolution measurements for all peaks in the chromatogram were reduced to a single numerical value using several functions: normalised by the mean resolution product, unnormalised product, geometrical mean of the unnormalised product, and worst elementary resolution value. The descriptive capability of these reduction functions was evaluated through the observation of global resolution diagrams and the change in the shape of the chromatograms in the selected factor space. michrom…
Measurement of the Md3+/Md2+ Reduction Potential Studied with Flow Electrolytic Chromatography
2013
The reduction behavior of mendelevium (Md) was studied using a flow electrolytic chromatography apparatus. By application of the appropriate potentials on the chromatography column, the more stable Md(3+) is reduced to Md(2+). The reduction potential of the Md(3+) + e(-) → Md(2+) couple was determined to be -0.16 ± 0.05 V versus a normal hydrogen electrode.
Positive Versions of Polynomial Time
1998
Abstract We show that restricting a number of characterizations of the complexity class P to be positive (in natural ways) results in the same class of (monotone) problems, which we denote by posP . By a well-known result of Razborov, posP is a proper subclass of the class of monotone problems in P . We exhibit complete problems for posP via weak logical reductions, as we do for other logically defined classes of problems. Our work is a continuation of research undertaken by Grigni and Sipser, and subsequently Stewart; indeed, we introduce the notion of a positive deterministic Turing machine and consequently solve a problem posed by Grigni and Sipser.
Noise-tolerant efficient inductive synthesis of regular expressions from good examples
1997
We present an almost linear time method of inductive synthesis restoring simple regular expressions from one representative (good) example. In particular, we consider synthesis of expressions of star-height one, where we allow one union operation under each iteration, and synthesis of expressions without union operations from examples that may contain mistakes. In both cases we provide sufficient conditions defining precisely the class of target expressions and the notion of good examples under which the synthesis algorithm works correctly, and present the proof of correctness. In the case of expressions with unions the proof is based on novel results in the combinatorics of words. A genera…
Efficient learning of regular expressions from good examples
1994
We consider the problem of restoring regular expressions from expressive examples. We define the class of unambiguous regular expressions, the notion of the union number of an expression showing how many union operations can occur directly under any single iteration, and the notion of an expressive example. We present a polynomial time algorithm which tries to restore an unambiguous regular expression from one expressive example. We prove that if the union number of the expression is 0 or 1 and the example is long enough, then the algorithm correctly restores the original expression from one good example. The proof relies on original investigations in theory of covering symbol sequences (wo…
Knot Theory, Jones Polynomial and Quantum Computing
2005
Knot theory emerged in the nineteenth century for needs of physics and chemistry as these needs were understood those days. After that the interest of physicists and chemists was lost for about a century. Nowadays knot theory has made a comeback. Knot theory and other areas of topology are no more considered as abstract areas of classical mathematics remote from anything of practical interest. They have made deep impact on quantum field theory, quantum computation and complexity of computation.
Co-morbidity does not reflect complexity in internal medicine patients
2006
Internal medicine patients are mostly elderly; they have multiple co-morbidities, which are usually chronic, rather than self-limiting or acute diseases. Neither administrative indicators nor co-morbidity indexes, though validated in elderly patients, are able to completely define these "complex" patients or to allow physicians to correctly "cope" with them. For the complex patients found in internal medicine wards, internists need not only to find the best diagnosis and treatment, but also to apply a complex intervention (i.e., a comprehensive assessment and both continuous and multi-disciplinary care) in order to maintain their health and ability to function and to prevent or delay disabi…