Search results for "Computer Aided Design"
showing 10 items of 40 documents
Error Estimates and Automatic Adaptive Mesh Refinement for the Metal Forming FEM Analysis
1988
The Authors propose a new technique which enables a estimation of the error inherent with the FEM analysis of metal forming processes. The aim is to evaluate the zones where the error is higher in order to proceed to a refinement of the mesh in such zones, and to obtain a smaller value of the global error. Moreover, to simplify the analyst work in the progressive refinement of the mesh, it has been prepared a software able to read the drawing created by a CAD program and to generate, automatically, all the geometrical and topological data necessary to perform the analysis on Personal Computer. The automatic renumbering of the elements in the refined mesh has been performed with the aim to r…
Fast Nash Hybridized Evolutionary Algorithms for Single and Multi-objective Design Optimization in Engineering
2014
Evolutionary Algorithms (EAs) are one of advanced intelligent systems and they occupied an important position in the class of optimizers for solving single-objective/reverse/inverse design and multi-objective/multi physics design problems in engineering. The chapter hybridizes the Genetic Algorithms (GAs) based computational intelligent system (CIS) with the concept of Nash-Equilibrium as an optimization pre-conditioner to accelerate the optimization procedure. Hybridized GAs and simple GAs are validated through solving five complex single-objective and multi-objective mathematical design problems. For real-world design problems, the hybridized GAs (Hybrid Intelligent System) and the origin…
Robotic path planning for non-destructive testing – A custom MATLAB toolbox approach
2016
AbstractThe requirement to increase inspection speeds for non-destructive testing (NDT) of composite aerospace parts is common to many manufacturers. The prevalence of complex curved surfaces in the industry provides motivation for the use of 6 axis robots in these inspections. The purpose of this paper is to present work undertaken for the development of a KUKA robot manipulator based automated NDT system. A new software solution is presented that enables flexible trajectory planning to be accomplished for the inspection of complex curved surfaces often encountered in engineering production. The techniques and issues associated with conventional manual inspection techniques and automated s…
Topological Approach to Drug Design
1995
In this paper we demonstrated that by an adequate combination of different topological indices it is possible to select and design new active compounds in different therapeutical scopes, with a very high efficiency level. Particularly successful in the search of new "lead drugs", the results show the surprising ability of the topological methods to describe molecular structures.
Multiresolution based on weighted averages of the hat function I: Linear reconstruction techniques
1998
In this paper we analyze a particular example of the general framework developed in [A. Harten, {\it SIAM J. Numer. Anal}., 33 (1996) pp. 1205--1256], the case in which the discretization operator is obtained by taking local averages with respect to the hat function. We consider a class of reconstruction procedures which are appropriate for this multiresolution setting and describe the associated prediction operators that allow us to climb up the ladder from coarse to finer levels of resolution. In Part I we use data-independent (linear) reconstruction techniques as our approximation tool. We show how to obtain multiresolution transforms in bounded domains and analyze their stability with r…
Introduction to molecular topology: basic concepts and application to drug design.
2012
In this review it is dealt the use of molecular topology (MT) in the selection and design of new drugs. After an introduction of the actual methods used for drug design, the basic concepts of MT are defined, including examples of calculation of topological indices, which are numerical descriptors of molecular structures. The goal is making this calculation familiar to the potential students and allowing a straightforward comprehension of the topic. Finally, the achievements obtained in this field are detailed, so that the reader can figure out the great interest of this approach.
The CALMA system: an artificial neural network method for detecting masses and microcalcifications in digitized mammograms
2004
The CALMA (Computer Assisted Library for MAmmography) project is a five years plan developed in a physics research frame in collaboration between INFN (Istituto Nazionale di Fisica Nucleare) and many Italian hospitals. At present a large database of digitized mammographic images (more than 6000) was collected and a software based on neural network algorithms for the search of suspicious breast lesions was developed. Two tools are available: a microcalcification clusters hunter, based on supervised and unsupervised feedforward neural network, and a massive lesions searcher, based on a hibrid approach. Both the algorithms analyzed preprocessed digitized images by high frequency filters. Clini…
Introducing a novel mesh following technique for approximation-free robotic tool path trajectories
2017
Abstract Modern tools for designing and manufacturing of large components with complex geometries allow more flexible production with reduced cycle times. This is achieved through a combination of traditional subtractive approaches and new additive manufacturing processes. The problem of generating optimum tool-paths to perform specific actions (e.g. part manufacturing or inspection) on curved surface samples, through numerical control machinery or robotic manipulators, will be increasingly encountered. Part variability often precludes using original design CAD data directly for toolpath generation (especially for composite materials), instead surface mapping software is often used to gener…
Optimization of fluorescence enhancement for silicon-based microarrays
2008
An optical technique for the enhancement of fluorescence detection sensitivity on planar samples is presented. Such a technique is based on the simultaneous optimization of excitation and light collection by properly combining interference and reflectance from the sample holder. Comparative tests have been performed in microarray applications, by evaluating the proposed solution against commercial glass-based devices, using popular labeling dyes, such as Cy3 and Cy5. The proposed technique is implemented on a substrate built with standard silicon technology and is therefore well suited for integrated micro total analysis systems (microTAS) applications.
Highly stable Zerodur based optical benches for microgravity applications and other adverse environments
2019
A number of cold atom experiments are restrained by the impeding effects of gravity. While efforts have been made to overcome these limitations in a gravitational environment, another approach is placing the experiment in a microgravity environment, as can be found aboard sounding rockets, satellites or a space station. The cornerstone of such experiments is a robust laser system. The adverse conditions during a rocket launch impose stringent requirements on thermal stability and resilience against mechanical stress on this part of the experimental setup. Furthermore, the very limited space found on any of the aforementioned microgravity platforms necessitates maximal miniaturization. In or…