Search results for "Computer Science Application"

Data Compression Approach for Long-Term Monitoring of Pavement Structures

2019

Pavement structures are designed to withstand continuous damage during their design life. Damage starts as soon as the pavement is open to traffic and increases with time. If maintenance activities are not considered in the initial design or considered but not applied during the service life, damage will grow to a point where rehabilitation may be the only and most expensive option left. In order to monitor the evolution of damage and its severity in pavement structures, a novel data compression approach based on cumulative measurements from a piezoelectric sensor is presented in this paper. Specifically, the piezoelectric sensor uses a thin film of polyvinylidene fluoride to sense the ener…

Pollutant Emissions in Ports: A Comprehensive Review

2021

In recent decades, maritime transport demand has increased along with world population and global trades. This is associated with higher pollution levels, including the emissions of GHG and other polluting gases. Ports are important elements within maritime transport and contribute themselves to pollutant emissions. This paper aims to offer a comprehensive yet technical review of the latest related technologies, explaining and covering aspects that link ports with emissions, i.e., analyzing, monitoring, assessing, and mitigating emissions in ports. This has been achieved through a robust scientific analysis of very recent and significant research studies, to offer an up-to-date and reliable…

Channel Assembling with Priority-Based Queues in Cognitive Radio Networks: Strategies and Performance Evaluation

2014

[EN] With the implementation of channel assembling (CA) techniques, higher data rate can be achieved for secondary users in multi-channel cognitive radio networks. Recent studies which are based on loss systems show that maximal capacity can be achieved using dynamic CA strategies. However the channel allocation schemes suffer from high blocking and forced termination when primary users become active. In this paper, we propose to introduce queues for secondary users so that those flows that would otherwise be blocked or forcibly terminated could be buffered and possibly served later. More specifically, in a multi-channel network with heterogeneous traffic, two queues are separately allocate…

Searching for New Physics in two-neutrino double beta decay with CUPID

2021

Abstract In the past few years, attention has been drawn to the fact that a precision analysis of two-neutrino double beta decay (2υββ) allows the study of interesting physics cases like the emission of Majoron bosons and possible Lorentz symmetry violation. These processes modify the summed-energy distribution of the two electrons emitted in 2υββ. CUPID is a next-generation experiment aiming to exploit 100Mo-enriched scintillating Li2MoO4 crystals, operating as cryogenic calorimeters. Given the relatively fast half-life of 100Mo 2υββ and the large exposure that can be reached by CUPID, we expect to measure with very high precision the 100Mo 2υββ spectrum shape, reaching great sensitivities…

Cancer-Related Cachexia: The Vicious Circle between Inflammatory Cytokines, Skeletal Muscle, Lipid Metabolism and the Possible Role of Physical Train…

2022

Cachexia is a multifactorial and multi-organ syndrome that is a major cause of morbidity and mortality in late-stage chronic diseases. The main clinical features of cancer-related cachexia are chronic inflammation, wasting of skeletal muscle and adipose tissue, insulin resistance, anorexia, and impaired myogenesis. A multimodal treatment has been suggested to approach the multifactorial genesis of cachexia. In this context, physical exercise has been found to have a general effect on maintaining homeostasis in a healthy life, involving multiple organs and their metabolism. The purpose of this review is to present the evidence for the relationship between inflammatory cytokines, skeletal mus…

Rebalancing β-Amyloid-Induced Decrease of ATP Level by Amorphous Nano/Micro Polyphosphate: Suppression of the Neurotoxic Effect of Amyloid β-Protein …

2017

Morbus Alzheimer neuropathology is characterized by an impaired energy homeostasis of brain tissue. We present an approach towards a potential therapy of Alzheimer disease based on the high-energy polymer inorganic polyphosphate (polyP), which physiologically occurs both in the extracellular and in the intracellular space. Rat pheochromocytoma (PC) 12 cells, as well as rat primary cortical neurons were exposed to the Alzheimer peptide Aβ25-35. They were incubated in vitro with polyphosphate (polyP); ortho-phosphate was used as a control. The polymer remained as Na+ salt; or complexed in a stoichiometric ratio to Ca2+ (Na-polyP[Ca2+]); or was processed as amorphous Ca-polyP microparticles (C…

2020

Endoplasmic reticulum (ER) calcium homeostasis plays an essential role in cellular calcium signaling, intra-ER protein chaperoning and maturation, as well as in the interaction of the ER with other organelles. Calcium is accumulated in the ER by sarco/endoplasmic reticulum calcium ATPases (SERCA enzymes) that generate by active, ATP-dependent transport, a several thousand-fold calcium ion concentration gradient between the cytosol (low nanomolar) and the ER lumen (high micromolar). SERCA enzymes are coded by three genes that by alternative splicing give rise to several isoforms, which can display isoform-specific calcium transport characteristics. SERCA expression levels and isoenzyme compo…

Exponential instability in the fractional Calder\'on problem

2017

In this note we prove the exponential instability of the fractional Calder\'on problem and thus prove the optimality of the logarithmic stability estimate from \cite{RS17}. In order to infer this result, we follow the strategy introduced by Mandache in \cite{M01} for the standard Calder\'on problem. Here we exploit a close relation between the fractional Calder\'on problem and the classical Poisson operator. Moreover, using the construction of a suitable orthonormal basis, we also prove (almost) optimality of the Runge approximation result for the fractional Laplacian, which was derived in \cite{RS17}. Finally, in one dimension, we show a close relation between the fractional Calder\'on pro…

WIN55,212-2-induced expression of Mir-29b1 favours the suppression of osteosarcoma cell migration in a SPARC-independent manner

2019

WIN55,212-2 (WIN) is a synthetic agonist of cannabinoid receptors that displays promising antitumour properties. The aim of this study is to demonstrate that WIN is able to block the migratory ability of osteosarcoma cells and characterize the mechanisms involved. Using wound healing assay and zymography, we showed that WIN affects cell migration and reduces the activity of the metalloproteases MMP2 and MMP9. This effect seemed to be independent of secreted protein acidic and rich in cysteine (SPARC), a matricellular protein involved in tissue remodeling and extracellular matrix deposition. SPARC release was indeed prevented by WIN, and SPARC silencing by RNA interference did not influence …

Quantitative global mapping of terrestrial vegetation photosynthesis

2017

Although traditional remote sensing systems based on spectral reflectance can already provide estimates of the 'potential' photosynthetic activity of terrestrial vegetation through the quantification of total canopy chlorophyll content or absorbed photosynthetic radiation, the determination of the 'actual' photosynthetic activity of terrestrial vegetation requires information about how the absorbed light is used by plants, such as vegetation fluorescence, using very high spectral resolution spectroscopy in the range 650-800 nm. The Fluorescence Explorer (FLEX) mission, selected in November 2015 as the 8th Earth Explorer by the European Space Agency (ESA), carries the FLORIS spectrometer, wi…