Search results for "Computer Science Applications"
showing 10 items of 3993 documents
Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance
2002
CD8+ T cells are the main effector cells for the immune control of cytomegaloviruses. To subvert this control, human and mouse cytomegaloviruses each encode a set of immune-evasion proteins, referred to here as immunoevasins, which interfere specifically with the MHC class I pathway of antigen processing and presentation. Although the concerted action of immunoevasins prevents the presentation of certain viral peptides, other viral peptides escape this blockade conditionally or constitutively and thereby provide the molecular basis of immune surveillance by CD8+ T cells. The definition of viral antigenic peptides that are presented despite the presence of immunoevasins adds a further dimens…
Infrared Microspectroscopy study of insulin crystals at high pressure
2012
During the last years the coupling of high pressure techniques and infrared spectroscopy has proven to be a very powerful tool in the study of conformational changes of proteins. Protein unfolding and monomerization are events that are expected to take place at high pressure due to the peculiarity of pressure to shift the system towards the state that occupies the minimum volume. We observed the growth of apparently cubic crystals at a pressure of about 4 kbar, subjecting to high pressure a solution of misfolded insulin. Even if high pressure is commonly used to tune the growth rate of crystals, protein crystallization at high pressure is not a well known process and no evidences of the par…
Projection of speckle patterns for 3D sensing
2008
In this communication we present the use of projected speckle patterns coming from a phase random mask for sensing depths and thicknesses. The sensing is based on the change of the speckle pattern with propagation and the lack of correlation between speckle patterns recorded at different depths or lateral locations. The principle is used for mapping thickness of transparent media, for depth ranging and for 3D mapping of diffuse objects.
Full field of view super-resolution imaging via two static masks
2008
The usage of two static gratings for obtaining super resolved imaging dates back to the work by Bachl and Lukosz in 1967. However, in that approach, a severe reduction in the field of view was the necessary condition for improving the resolution. In this paper we present two approaches that are also based upon two static gratings but without the need to sacrifice in the field of view. The key idea for not paying with the field of view is performed in two ways: First, by using white light illumination that averages the ghost images obtained outside the region of interest since the positions of those images are wavelength dependent. Second, by using two random functions for the encoding and t…
Ab initio molecular dynamics simulations of the Sc K-edge EXAFS of scandium trifluoride
2016
Scandium fluoride ScF3 has a simple cubic structure and attracts attention due to its large negative thermal expansion (NTE) over a wide range of temperatures (0-1100 K). In this study we present ab initio molecular dynamics (AIMD) simulations of ScF3 and their validation using the Sc K-edge EXAFS spectra in the temperature range from 300 K to 1000 K measured at the XAFS beamline of ELETTRA. The obtained results allow an assessement of the employed AIMD model and provide insight into the local structure and the lattice dynamics of ScF3 beyond the harmonic approximation. A strong anisotropy of the fluorine atom vibrations in the direction orthogonal to the -Sc-F-Sc- chain is observed. An exp…
Project-based learning in a computer modelling course
2021
AbstractThe paper reports authors’ experience of implementing educational projects in a computer modelling course offered to the students majoring in “Secondary Education (Computer Science)” at Ternopil Volodymyr Hnatiuk National Pedagogical University. We analyze approaches to teaching mathematical and computer modelling such as: integration of modelling tasks, naturalistic case study, using of role-playing games, possibilities of STEM-education, motivation and positive attitude to modelling training, etc. Then we illustrate the implementation of the project to study the population dynamics of the grape snail Helix pomatia. The implementation of the project splits into several stages: form…
Recent results on heavy-ion induced reactions of interest for neutrinoless double beta decay at INFN-LNS
2019
Abstract The NUMEN project aims at accessing experimentally driven information on Nuclear Matrix Elements (NME) involved in the half-life of the neutrinoless double beta decay (0νββ). In this view measurements of Heavy Ion (HI) induced Double Charge Exchange (DCE) reaction cross sections are performed with high-accuracy. In particular, the (18O,18Ne) and (20Ne,20O) reactions are used as tools for β+β+ and β-β- decays, respectively. In the experiments, performed at INFN - Laboratory Nazionali del Sud (LNS) in Catania, the beams are accelerated by the Superconducting Cyclotron (CS) and the reaction ejectiles are detected the MAGNEX magnetic spectrometer. The measured cross sections are challe…
Dry deposition of particle on urban areas
2019
Abstract Dry deposition process is recognized as an important pathway among the removal processes of radioactive pollutants in atmosphere. There is not a unique and accepted theoretical description of involved dry deposition phenomena due to the complexity of the fluid-dynamic processes that influence the deposition flux, but also because there is a lack of experimental data covering all scenarios of interest. In this paper, that is the result of a National Research Program a research activity conducted by DEIM Department of the University of Palermo and ENEA and funded by the Italian Minister of Economic Development, a new schema for parameterization of particle dry deposition velocity on …
Empirical study of multidimensional Child-Langmuir law with plasma ion source extraction using round apertures
2022
Abstract One dimensional Child-Langmuir (CL) law is commonly used in ion source physics to describe space charge limited ion extraction from the plasma. Recently 2D and 3D CL laws have been derived, but plasma ion extraction does not strictly meet the assumptions in these CL laws. Investigations on the applicability of the CL laws to ion source extraction were conducted using filament-driven ion source, measuring the beam currents as a function of extraction voltage. The experiments are complemented with simulations where IBSimu is used for studying the behaviour of plasma meniscus. Three different voltage regions were identified with low, moderate and high voltage. With moderate voltages t…
Measurement of ionization, charge exchange and ion confinement times in charge breeder ECR ion sources with short pulse 1+ injection of metal ions
2022
Abstract The Consecutive Transients (CT) method is used for estimating the characteristic times of ionization, charge exchange and confinement within the plasma of a Charge Breeder Electron Cyclotron Resonance Ion Source (CB-ECRIS). The method reveals differences in the characteristic times between different source configurations, with K9+ charge breeding efficiencies of 8.9 % and 20.4 %, and allows qualitative explanation of the improved breeding efficiency. The increase in K9+ efficiency is accompanied by a decrease in ionization time for low charge states, a decrease of charge exchange time for high charge states, and an overall decrease of the ion confinement time, which increases non-l…