Search results for "Computer-aided"
showing 10 items of 416 documents
Computer-Aided Diagnosis for Prostate Cancer using Multi-Parametric Magnetic Resonance Imaging
2016
Prostate cancer (CaP) is the second most diagnosed cancer in men all over the world.CaP growth is characterized by two main types of evolution: (i) the slow-growing tumours progress slowly and usually remain confined to the prostate gland; (ii) the fast-growing tumours metastasize from prostate gland to other organs, which might lead to incurable diseases.Therefore, early diagnosis and risk assessment play major roles in patient treatment and follow-up.In the last decades, new imaging techniques based on Magnetic Resonance Imaging (MRI) have been developed improving diagnosis.In practise, diagnosis can be affected by multiple factors such as observer variability and visibility and complexit…
A potential solution to avoid overdose of mixed drugs in the event of Covid-19: Nanomedicine at the heart of the Covid-19 pandemic.
2021
Since 2020, the world is facing the first global pandemic of 21st century. Among all the solutions proposed to treat this new strain of coronavirus, named SARS-CoV-2, the vaccine seems a promising way but the delays are too long to be implemented quickly. In the emergency, a dual therapy has shown its effectiveness but has also provoked a set of debates around the dangerousness of a particular molecule, hydroxychloroquine. In particular, the doses to be delivered, according to the studies, were well beyond the acceptable doses to support the treatment without side effects. We propose here to use all the advantages of nanovectorization to address this question of concentration. Using quantum…
Singularities of rational Bézier curves
2001
We prove that if an nth degree rational Bezier curve has a singular point, then it belongs to the two (n − 1)th degree rational Bezier curves defined in the (n − 1)th step of the de Casteljau algorithm. Moreover, both curves are tangent at the singular point. A procedure to construct Bezier curves with singularities of any order is given. 2001 Elsevier Science B.V. All rights reserved.
Iterative construction of Dupin cyclides characteristic circles using non-stationary Iterated Function Systems (IFS)
2012
International audience; A Dupin cyclide can be defined, in two different ways, as the envelope of an one-parameter family of oriented spheres. Each family of spheres can be seen as a conic in the space of spheres. In this paper, we propose an algorithm to compute a characteristic circle of a Dupin cyclide from a point and the tangent at this point in the space of spheres. Then, we propose iterative algorithms (in the space of spheres) to compute (in 3D space) some characteristic circles of a Dupin cyclide which blends two particular canal surfaces. As a singular point of a Dupin cyclide is a point at infinity in the space of spheres, we use the massic points defined by J.C. Fiorot. As we su…
Dupin Cyclide Blends Between Quadric Surfaces for Shape Modeling
2004
We introduce a novel method to define Dupin cyclide blends between quadric primitives. Dupin cyclides are nonspherical algebraic surfaces discovered by French mathematician Pierre-Charles Dupin at the beginning of the 19th century. As a Dupin cyclide can be fully characterized by its principal circles, we have focussed our study on how to determine principal circles tangent to both quadrics being blended. This ensures that the Dupin cyclide we are constructing constitutes aG 1 blend. We use the Rational Quadratic Bezier Curve (RQBC) representation of circular arcs to model the principal circles, so the construction of each circle is reduced to the determination of the three control points o…
Dupin cyclide blends between non-natural quadrics of revolution and concrete shape modeling applications
2014
Abstract In this work, we focus on the blending of two quadrics of revolution by two patches of Dupin cyclides. We propose an algorithm for the blending of non-natural quadrics of revolution by decomposing the blending operation into two complementary sub-blendings, each of which is a Dupin cyclide-based blending between one of the two quadrics and a circular cylinder, thus enabling the direct computation of the two Dupin cyclide patches and offering better flexibility for shape composition. Our approach uses rational quadric Bezier curves to model the relevant arcs of the principal circles of Dupin cyclides. It is quite general and we have successfully used it for the blending of several n…
An isoperimetric type problem for primitive Pythagorean hodograph curves
2012
An isoperimetric type problem for primitive Pythagorean hodograph curves is studied. We show how to compute, for each possible degree, the Pythagorean hodograph curve of a given perimeter enclosing the greatest area. We also discuss the existence and construction of smooth solutions, obtaining a relationship with an interesting sequence of Appell polynomials.
An annihilator-based strategy for the automatic detection of exponential polynomial spaces in subdivision
2021
Abstract Exponential polynomials are essential in subdivision for the reconstruction of specific families of curves and surfaces, such as conic sections and quadric surfaces. It is well known that if a linear subdivision scheme is able to reproduce a certain space of exponential polynomials, then it must be level-dependent, with rules depending on the frequencies (and eventual multiplicities) defining the considered space. This work discusses a general strategy that exploits annihilating operators to locally detect those frequencies directly from the given data and therefore to choose the correct subdivision rule to be applied. This is intended as a first step towards the construction of se…
Introducing a novel mesh following technique for approximation-free robotic tool path trajectories
2017
Abstract Modern tools for designing and manufacturing of large components with complex geometries allow more flexible production with reduced cycle times. This is achieved through a combination of traditional subtractive approaches and new additive manufacturing processes. The problem of generating optimum tool-paths to perform specific actions (e.g. part manufacturing or inspection) on curved surface samples, through numerical control machinery or robotic manipulators, will be increasingly encountered. Part variability often precludes using original design CAD data directly for toolpath generation (especially for composite materials), instead surface mapping software is often used to gener…
Optimization of fluorescence enhancement for silicon-based microarrays
2008
An optical technique for the enhancement of fluorescence detection sensitivity on planar samples is presented. Such a technique is based on the simultaneous optimization of excitation and light collection by properly combining interference and reflectance from the sample holder. Comparative tests have been performed in microarray applications, by evaluating the proposed solution against commercial glass-based devices, using popular labeling dyes, such as Cy3 and Cy5. The proposed technique is implemented on a substrate built with standard silicon technology and is therefore well suited for integrated micro total analysis systems (microTAS) applications.