Search results for "Computer"
showing 10 items of 30657 documents
Graphene nanosystems as supports in siRNA Delivery
2018
The nature of graphene-based nanosystems, as well as the possibility to synthesize them at low cost, have made them in the last few years, an interesting proposition in tumour therapy as a drug delivery system. Here, a reduced form of graphene oxide (RGO) has been synthesized and conjugated with a specific antibody for active targeting against tumour cells (RGOY). Furthermore, its bi-dimensional nature permits also p- p stacking interactions with planar molecules like siRNA (RGOY-siRNA). All these nano-complexes were characterized by DLS and DSC analysis, TEM and Raman spectroscopy and their biocompatibility was demonstrated by viability assay on cell line ECV 304. The system is able to be …
Formulation of Different Chitosan Hydrogels for Cartilage Tissue Repair
2014
Different formulations of Chitosan/sulphate and Chitosan/PEGDE were produced by physical and chemical reticulation to obtain hydrogels with better physiochemical properties. The hydrogels were analyzed – in terms of their non-toxicity, proliferative, differentiative, inflammatory and immunology responses. Commercial grade Chitosan (Sigma) was solubilized and purified by progressive filtrations. Then, the polymer was freeze-dried in a water soluble cationic form. A physical hydrogel was prepared by mixing a 3 % w/w water solution of the a.m. polymer with different stoichiometric ratios of (SO4=) 1/0.5;1/0.75;1/1 respectively. The hydrogels were cross-linked in multiwells. The chemical hydrog…
Fabrication and characterization of nanostructured Ni and Pd electrodes for hydrogen evolution reaction (HER) in water-alkaline electrolyzer
2017
In the field of water-alkaline electrolyzer, the development of nanoporous low cost nickel electrodes is one of the potential approaches to increase electrocatalytic activity. Template electrodeposition is a facile and cheap technique for obtaining Ni nanowires (NWs) with high surface area. These nanostructures were fabricated by a two-step procedure. In the first step, a Ni compact layer was deposited on one side of the template where a gold film was previously sputtered, while, in the second-step, an ordered array of Ni-NWs was obtained by electrodeposition inside the template channels. The NWs were firmly connected to the underlying Ni layer, acting as a current collector. In order to en…
EOF-Library: Open-source Elmer FEM and OpenFOAM coupler for electromagnetics and fluid dynamics
2019
EOF-Library is a software that couples Elmer and OpenFOAM simulation packages. It enables efficient internal field interpolation and communication between the finite element and the finite volume frameworks. The coupling of the two packages is based on the Message Passing Interface, which results in low latency, high data bandwidth and parallel scalability. Potential applications are magnetohydrodynamics, convective cooling of electrical devices, industrial plasma physics and microwave heating. In this work we introduce the software and perform interpolation accuracy and parallel scaling tests by sending a known scalar distribution between the two codes. Keywords: Elmer, FEM, OpenFOAM, FVM,…
Do Software Firms Collaborate or Compete? A Model of Coopetition in Community-initiated OSS Projects
2019
[Background] An increasing number of commercial firms are participating in Open Source Software (OSS) projects to reduce their development cost and increase technical innovativeness. When collaborating with other firms whose sought values are conflicts of interests, firms may behave uncooperatively leading to harmful impacts on the common goal. [Aim] This study explores how software firms both collaborate and compete in OSS projects. [Method] We adopted a mixed research method on three OSS projects. [Result] We found that commercial firms participating in community-initiated OSS projects collaborate in various ways across the organizational boundaries. While most of firms contribute little,…
Spatiotemporal hotspots analysis for exploring the evolution of diseases: An application to oto-laryngopharyngeal diseases
2013
Abstract View references (14) This paper presents a spatiotemporal analysis of hotspot areas based on the Extended Fuzzy C-Means method implemented in a geographic information system. This method has been adapted for detecting spatial areas with high concentrations of events and tested to study their temporal evolution. The data consist of georeferenced patterns corresponding to the residence of patients in the district of Naples (Italy) to whom a surgical intervention to the oto-laryngopharyngeal apparatus was carried out between the years 2008 and 2012
Analysis and Performance Evaluation of the IEEE 802.16 ARQ Mechanism
2008
The IEEE 802.16 standard defines the ARQ mechanismas a part of the MAC layer. The functioning of the ARQmechanism depends on a number of parameters. The IEEE802.16 specification defines them but it does not provide concrete values and solutions. This paper studies the key features and parameters of the 802.16 ARQ mechanism. In particular, we consider a choice for the ARQ feedback type, an algorithm to build block sequences, the ARQ feedback intensity, a scheduling of the ARQ feedbacks and retransmissions, the ARQ block rearrangement, ARQ transmission window and the ARQ block size. We ran simulation scenarios to study these parameters and how they impact the performance of application protoc…
Software Startups – A Research Agenda
2016
Software startup companies develop innovative, software-intensive products within limited timeframes and with few resources, searching for sustainable and scalable business models. Softwarestartups are quite distinct from traditional mature software companies, but also from micro-,small-, and medium-sized enterprises, introducing new challenges relevant for software engineeringresearch. This paper’s research agenda focuses on software engineering in startups, identifying,in particular, 70+ research questions in the areas of supporting startup engineering activities,startup evolution models and patterns, ecosystems and innovation hubs, human aspects in softwarestartups, applying startup conc…
Fuzzy Methods and Approximate Reasoning in Geographical Information Systems
2014
This issue has been dedicated to the usage of fuzzy logic in the context of Geographical Information Systems (GIS) and were receveid the following papers whose contents are described below: - in the paper of A. Hofmann, S. Hoskova-Mayerova, and V. Talhofer, the authors use a GIS tool which is useful to study the influence of geographic and climatic factors on the terrain passability of armed forces and the Integrated Rescue System. - In the first paper of S. Sessa and F. Di Martino, the authors propose the usage of the well known Extended Gustafson-Kessel clustering method, encapsulated in a GIS tool, for detecting hotspots in spatial analysis. The data consist of geo-referenced patterns co…
The Electronic Historical Latvian Dictionary Based on the Corpus of Early Written Latvian Texts
2016
The Electronic Historical Latvian Dictionary Based on the Corpus of Early Written Latvian Texts This article deals with the development of the Electronic Historical Latvian Dictionary (http://www.tezaurs.lv/lvvv) based on the Corpus of Early Written Latvian Texts (http://www.korpuss.lv/senie/). Some issues concerning the compilation and processing of the corpus data are discussed and the main sources added to the Corpus during the four-year project are described: the 16th c. Lord’s Prayers , 17th c. dictionaries, texts of oaths and laws, religious texts and so-called dedication poetry. The aim of the project is to compile a pilot electronic dictionary of 16th–17th century Latvian where all…