Search results for "Concentrate"

showing 10 items of 45 documents

Angioedema due to acquired C1-inhibitor deficiency: spectrum and treatment with C1-inhibitor concentrate

2018

Abstract Background Acquired angioedema due to C1-inhibitor (C1-INH) deficiency (AAE-C1-INH) is a serious condition that may result in life-threatening asphyxiation due to laryngeal edema. It is associated with malignant B-cell lymphoma and other disorders. The purpose of this study was to describe the characteristics and associated disorders of patients with AAE-C1-INH and assess the efficacy of plasma-derived C1-INH concentrate (pdC1-INH) in the treatment of AAE-C1-INH. Forty-four patients with AAE-C1-INH from the Angioedema Outpatient Service of Mainz were assessed for associated disorders. In 32 of these patients, the duration of swelling attacks was measured before and after treatment …

Male0301 basic medicinelcsh:Medicine030105 genetics & heredityGastroenterologyAcquired angioedemaC1-inhibitor0302 clinical medicineGermanyImmunology and Allergyheterocyclic compoundsPharmacology (medical)Genetics (clinical)Non-Hodgkin lymphomaAged 80 and overC1-inhibitor deficiencybiologyGeneral MedicineMiddle Agedrespiratory systemTreatment OutcomeC1-inhibitor concentrate C1-inhibitor antibodiesFemalemedicine.symptomComplement C1 Inhibitor ProteinAdultmedicine.medical_specialtyC1 inhibitor deficiencyImmunologyMalignancyLaryngeal Edema03 medical and health sciencesInternal medicinemedicineHumansAngioedemaAgedRetrospective StudiesAngioedemabusiness.industryResearchlcsh:RAngioedemas HereditaryAutoantibodybiochemical phenomena metabolism and nutritionbacterial infections and mycosesmedicine.diseaserespiratory tract diseasesLymphomabiology.proteinbusiness030217 neurology & neurosurgeryMonoclonal gammopathy of undetermined significanceOrphanet Journal of Rare Diseases
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Activated prothrombin complex concentrate (FEIBA® ) in acquired haemophilia A: a large multicentre Italian study - the FAIR Registry

2019

MalePediatricsmedicine.medical_specialtyhaemophiliacoagulation factors030204 cardiovascular system & hematologyHemophilia AHaemophilia03 medical and health sciences0302 clinical medicineAcquired haemophiliaHumansMedicinecoagulation factorProspective StudiesRegistriesProspective cohort studyActivated prothrombin complex concentrateRetrospective Studiesbleeding disorders; coagulation factors; factor VIII; haemophilia; Blood Coagulation Factors; Female; Hemophilia A; Humans; Italy; Male; Prospective Studies; Retrospective Studies; Registriesbleeding disordersbleeding disorderbusiness.industryRetrospective cohort studyHematologymedicine.diseaseBlood Coagulation FactorsItalyfactor VIIIFemalebusiness030215 immunologyBritish Journal of Haematology
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Low dose of aPCC after the initial treatment in acquired haemophilia A is useful to reduce bleeding relapses: Data from the FAIR registry

2019

Background: Bypassing agents are the first line therapy in patients with acquired haemophilia A (AHA). Activated prothrombin complex concentrate (aPCC) proved to be effective as initial treatment, but 20% of patients (pts) had relapses. aPCC as short-term prophylaxis to reduce subsequent bleeds is still not clear. Aim: To evaluate whether a short-term prophylaxis with low dose of aPCC can reduce bleeding relapses after initial AHA treatment, maintaining safety. Methods: The FAIR Registry is a retrospective-prospective study started on December 2012, that collected data on all pts with AHA treated with aPCC in 12 Italian Haemophilia Centers. All statistical analyses were carried out in the 5…

Malemedicine.medical_specialtyAcquired haemophilia; Bleeding relapses; Bypassing agents; Prophylaxis; Aged; Female; Hemophilia A; Hemorrhage; Humans; Male; Prospective Studies; Recombinant Proteins; Recurrence; Retrospective StudiesHemorrhage030204 cardiovascular system & hematologyHemophilia AHaemophilia03 medical and health sciences0302 clinical medicineFirst line therapyRecurrenceInternal medicineAcquired haemophiliamedicineHumansInitial treatmentIn patientProspective StudiesProphylaxiActivated prothrombin complex concentrateBypassing agentAgedRetrospective StudiesHematologyProphylaxisbusiness.industryLow doseBleeding relapseHematologymedicine.diseaseRecombinant Proteins030220 oncology & carcinogenesisFemaleBleeding relapsesBypassing agentsbusinessAcquired haemophiliaThrombosis Research
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L’inclusione vista dagli alunni: costruzione e validazione del questionario per rilevare la qualità inclusiva della scuola

2018

Molti studi nazionali e internazionali si sono concentrati sulla valutazione e sulla promozione della qualità inclusiva della scuola. Si tratta di un argomento complesso, che ha stimolato un ampio dibattito e una varietà di contributi che mettono in luce la necessità di uno strumento in grado di misurare la qualità inclusiva delle nostre scuole, per determinare l’evidenza empirica riguardo a questo tema. L’articolo presenta i risultati di una sperimentazione finalizzata alla redazione di un questionario per la rilevazione della qualità inclusiva del sistema scolastico percepita dagli alunni. Il questionario si pone come uno strumento di valutazione e autovalutazione che permette la misurazi…

Many national and international studies have concentrated on the evaluation and promotion of the inclusive qualities of schools. It is a complex issue which has led to wide debate and a variety of contributions which in turn highlight the need for a tool capable of measuring the inclusive quality of our schools in order to determine the empirical evidence regarding this topic. This article presents the results of an experiment in drafting a questionnaire in order to measure the inclusive quality of the school system perceived by its pupils. The questionnaire is intended as an evaluation and selfevaluation tool that enables the inclusive quality generated by the context to be measured as it is perceived by pupils. At the same time the tool allows reflection processes amongst teachers to be promoted so that they can implement educational activities which contribute to the planning and control of inclusive teaching practices. This contribution puts forward an original tool for measuring the inclusive quality of the school system perceived by pupils attending primary school in several Sicilian towns. It was administered in its definitive version to a sample of 1652 children. The psychometric properties of the tool and the significance it can hold in the areas of planning in research and of educational design are presented in this paper.Settore M-PED/03 - Didattica E Pedagogia Speciale
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A study of solar thermal absorber stack based on CrAlSiNx/CrAlSiNxOy structure by ion beams

2019

Renewable energies are foreseen as a major energy resource for next generations. Among several energy sources and technologies available, Concentrated Solar Power (CSP) technology has a great potential, but it needs to be optimised, in particular to reduce the costs, with an increase of the operating temperature and long term stability. This goal can be achieved by tailoring the composition and multilayer structure of films. In this work we present and discuss the results obtained from solar absorber coatings based on nitride/oxynitride structures. A four-layer film structure, W/CrAlSiNx(HA)/CrAlSiNxOy(LA)/SiAlOx, was deposited on stainless steel substrates using magnetron sputtering deposi…

Nuclear and High Energy PhysicsMaterials scienceCrAlSiNx /CrAlSiNxOy02 engineering and technologyaurinkoenergia010402 general chemistry01 natural sciences7. Clean energyRutherford Backscattering Spectrometry (RBS)time of flight elastic recoil detection analysis (TOF-ERDA)Operating temperatureSputteringConcentrated solar power:Engenharia dos Materiais [Engenharia e Tecnologia]Thermal stabilityCrAlSiN /CrAlSiN O x x yInstrumentationpinnoitteetTime of flight Elastic Recoil Detection Analysis (TOF-ERDA)CrAlSiNx/CrAlSiNxOyScience & TechnologySolar selective absorberbusiness.industrySputteringSolar selective absorber ; Rutherford Backscattering Spectrometry (RBS) ; Time of flight Elastic Recoil Detection Analysis (TOF-ERDA) ; CrAlSiNx/CrAlSiNxOySputteringSputter deposition021001 nanoscience & nanotechnologyRutherford backscattering spectrometry0104 chemical sciencesElastic recoil detectionsolar selective absorberspektrometriaEngenharia e Tecnologia::Engenharia dos MateriaisOptoelectronicssputteringohutkalvot0210 nano-technologybusinessEnergy source
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The Hu-Washizu variational principle for the identification of imperfections in beams

2008

This paper presents a procedure for the identification of imperfections of structural parameters based on displacement measurements by static tests. The proposed procedure is based on the well-known Hu–Washizu variational principle, suitably modified to account for the response measurements, which is able to provide closed-form solutions to some inverse problems for the identification of structural parameter imperfections in beams. Copyright © 2008 John Wiley & Sons, Ltd.

Numerical AnalysisMathematical optimizationEstimation theoryApplied MathematicsGeneral EngineeringSystem identificationInverse problemDisplacement (vector)static testsconcentrated damageIdentification (information)Exact solutions in general relativityVariational principleApplied mathematicsimperfectionsCalculus of variationsSettore ICAR/08 - Scienza Delle CostruzioniHu-Washizu variational principlestructural parameter identificationMathematicsInternational Journal for Numerical Methods in Engineering
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Adverse Events in Treatment of Inherited Factor VII Deficiency: Final Analysis of the STER

2012

Abstract Abstract 2279 Introduction No evidence-based guidelines are available for the treatment of Factor VII deficiency. Replacement therapy (RT) is still influenced by different factors as rarity of the disorder, availability and supply of products and economic reasons. All RTs are not exempt of side effects and scanty data is available about the safety of the products currently used. Aim of this study was to analyze adverse events (AEs) of RTs for congenital Factor VII deficiency, as reported in Seven Treatment Evaluation Registry (STER). Design and Methods FVII deficiency patients treated for bleeding episodes, prophylaxis, and surgery were investigated for RT-related AEs over a period…

Pediatricsmedicine.medical_specialtySuperficial vein thrombosisFactor VIIbusiness.industryImmunologyAdverse Events Inherited Fasctor VII deficiencyCell BiologyHematologymedicine.diseaseBiochemistryThrombosisProthrombin complex concentratechemistry.chemical_compoundchemistryMedicineObservational studyFresh frozen plasmabusinessFactor VII deficiencyAdverse effectmedicine.drug
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Hyper-concentrated flow and surface velocity estimation by digital imaging technique: a study case

2015

This paper investigates the utility of digital imaging technique for performing surface velocity measurements of hyper-concentrated flows. The analysis is conducted with the aid of data collected in a scale laboratory flume constructed at the Hydraulic laboratory of the Department of Civil, Environmental, Aerospatial and of Materials Engineering (DICAM) – University of Palermo (Italy). In particular the present paper describes the setup of a laboratory test and the applicability of a fully digital imaging approach.

Predictions hyper-concentrated flows flow velocity experiments digital measurementsSettore ICAR/01 - Idraulica
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Recomendaciones de uso de los anticoagulantes orales directos en el período perioperatorio

2012

Because of the characteristics of direct oral anticoagulants (DOA), the lack of an antidote to completely reverse their anticoagulant effects, the absence of standardization in monitoring of their effects, and limited experience of their use, specific recommendations for their management in the perioperative period or in emergencies are required. In elective surgery, in patients with normal renal function and low hemorrhagic/ thrombotic risk, DOA should be withdrawn 2 days before the intervention; when the hemorrhagic/ thrombotic risk is higher, bridge therapy with a low molecular weight hepatin beginning 5 days before the intervention is proposed as an alternative. In emergency surgery, sy…

Rivaroxabanmedicine.drug_classbusiness.industrymedicine.medical_treatmentAnticoagulantGeneral MedicinePerioperativemedicine.diseaseThrombosisProthrombin complex concentrateDabigatranAnesthesiamedicineElective surgeryAntidotebusinessmedicine.drugMedicina Clínica
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Diffuse and concentrated pollution control at watershed-scale: an Italian case study

2008

Settore ICAR/03 - Ingegneria Sanitaria-AmbientaleSettore ICAR/02 - Costruzioni Idrauliche E Marittime E IdrologiaDiffuse and concentrated pollution water body
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