Search results for "Concentrate"

showing 10 items of 45 documents

Combined use of antifibrinolytics and activated prothrombin complex concentrate (aPCC) is not related to thromboembolic events in patients with acqui…

2019

Antifibrinolytics combined with aPCC are not routinely administered to patients with acquired hemophilia A due to increased thrombotic risk. This association normalizes clot stability, and improves the efficacy of therapy, but can increase the risk of severe side effects. Due to these premises it has always raised doubts and perplexities in the clinics. We now report the data of the "FEIBA® on acquired haemophilia A Italian Registry (FAIR Registry)", a retrospective-prospective study that included 56 patients. This is the first study that assessed the clinical response of the combination of aPCC and antifibrinolytic agents in patients with acquired haemophilia A. A total of 101 acute bleeds…

medicine.medical_specialtyAntifibrinolyticmedicine.drug_classHemorrhage030204 cardiovascular system & hematologyHemophilia APremises03 medical and health sciences0302 clinical medicineDrug TherapyThromboembolismAntifibrinolytic agentInternal medicineActivated prothrombin complex concentrateAcquired haemophiliaThromboembolic riskHumansMedicineIn patientRegistries030212 general & internal medicineAcquired haemophilia AHematologybusiness.industryHematologyAcquired haemophilia A; Activated prothrombin complex concentrate; Antifibrinolytics; Thromboembolic risk; Antifibrinolytic Agents; Blood Coagulation Factors; Cardiovascular Diseases; Drug Therapy Combination; Hemophilia A; Hemorrhage; Humans; Registries; ThromboembolismAntifibrinolytic AgentsBlood Coagulation FactorsClinical trialTolerabilityCardiovascular DiseasesCombinationAntifibrinolyticDrug Therapy CombinationAntifibrinolyticsCardiology and Cardiovascular Medicinebusiness
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Extraordinary sediment delivery and rapid geomorphic response following the 2008-2009 eruption of Chaitén Volcano, Chile

2016

U.S. Geological Survey Volcano Science Center SERNAGEOMIN's Programa de Riesgos Volcanicos Conicyt Fondecyt grants 1110609 1141064 11130671 Conicyt Fondap 15090013 Vamos Research Centre

HydrologySediment yieldgeographygeography.geographical_feature_category010504 meteorology & atmospheric sciencesSediment010502 geochemistry & geophysics01 natural sciencesVolcanoHyperconcentrated flowResearch centreGeological surveySuspended loadGeomorphologyGeology0105 earth and related environmental sciencesWater Science and TechnologyWater Resources Research
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Physicochemical stability of irinotecan injection concentrate and diluted infusion solutions in PVC bags

2000

Purpose. To determine the physicochemical stability of irinotecan injection concentrate and irinotecan infusion solutions after dilution in two commonly used infusion fluids (0.9% sodium chloride, 5% dextrose) in PVC bags, stored under refrigeration (2-8°C) or at room temperature either light protected or exposed to light. Methods. Stability of irinotecan injection concentrate was determined in the original amber glass vials. Diluted irinotecan infusion solutions were aseptically prepared by further dilution of irinotecan stock solution with either 0.9% sodium chloride or 5% dextrose in PVC bags, in amounts yielding irinotecan concentrations of 0.4, 1.0, or 2.8 mg/ml. Test solutions were s…

medicine.medical_specialtyChromatographybusiness.industryInfusion solutionSodiumchemistry.chemical_elementInjection concentrateDilutionSurgeryIrinotecan03 medical and health sciences0302 clinical medicineIrinotecan InjectionOncologychemistry030220 oncology & carcinogenesisMedicinePharmacology (medical)business030215 immunologymedicine.drugJournal of Oncology Pharmacy Practice
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Determination of differential leakage factors in electrical machines with non-symmetrical full and dead-coil windings

2017

In this paper Gorges polygons are used in conjunction with masses geometry to find an easy and affordable way to compute the differential leakage factor of non symmetrical full and dead coil winding. By following the traditional way, the use of the Ossanna's infinite series which has to be obviously truncated under the bound of a predetermined accuracy is mandatory. In the presented method no infinite series is instead required. An example is then shown and discussed to demonstrate practically the effectiveness of the proposed method.

010302 applied physicsConcentrated windingSettore ING-IND/32 - Convertitori Macchine E Azionamenti Elettrici01 natural sciencesDifferential leakage factorwindingsmoment of inertiaControl theoryElectromagnetic coil0103 physical sciencesunsymmetrical windingGörges polygonLeakage (electronics)Mathematics
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Autologous adipose-derived stromal vascular fraction and platelet concentrates for the treatment of complex perianal fistulas

2022

Abstract Background Complex perianal fistulas are a major challenge for modern surgery since 10–35% of patients have functional problems after treatment. Sphincter-saving techniques have a wide range of efficacy (10–80%). We hypothesised that autologous adipose-derived stromal vascular fraction in combination with platelet rich plasma is a new therapeutic strategy with enhanced cure and function preservation rates. Methods Adult patients with complex cryptoglandular perianal fistulas were treated with injection of autologous adipose-derived stromal vascular fraction in combination with platelet rich plasma around and inside the fistulous tract between May 2018 and April 2019 at the General …

CryptoglandularPlatelet concentratesGastroenterologySurgerySettore MED/46 - Scienze Tecniche Di Medicina Di LaboratorioPerianal fistulaStromal cellsTechniques in Coloproctology
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Understanding trends and drivers of urban poverty in American cities

2022

Urban poverty arises from the uneven distribution of poor populations across neighborhoods of a city. We study the trend and drivers of urban poverty across American cities over the last 40 years. To do so, we resort to a family of urban poverty indices that account for features of incidence, distribution, and segregation of poverty across census tracts. Compared to the universally-adopted concentrated poverty index, these measures have a solid normative background. We use tract-level data to assess the extent to which demographics, housing, education, employment, and income distribution affect levels and changes in urban poverty. A decomposition study allows to single out the effect of cha…

American Community SurveyStatistics and ProbabilityCensusEconomics and EconometricsMathematics (miscellaneous)Oaxaca–Blinder decompositionCensuGini indexSpatial inequalityConcentrated povertySocial Sciences (miscellaneous)Empirical Economics
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MED parallel system powered by concentrating solar power (CSP): model and case study: Trapani, Sicily

2014

Abstract: This work presents an overlook on a new model that simulates the physical operation in steady state of a multi-effect distillation (MED) plant with parallel-feed (P) configuration. This model includes the consumption of steam with steam ejectors, and its validation was done using data from a real MED industrial plant using a thermal vapor compressor (TVC) operating in Italy, in the Sicilian city of Trapani. Results show that the MED model returns accurate predictions of the plant behavior, very useful for a first analysis on such type of investments. This MED model was also integrated into the system advisor model developed by the US National Renewable Energy Laboratory. Simulatio…

EngineeringParallel MED desalination model concentrated solar powerOcean EngineeringTRNSYS7. Clean energyDesalinationCogenerationCSPConcentrated solar powerMulti-effect-desalinationThermody- namic simulationThermodynamic simulationProcess engineeringSolar powerConcentrating solar powerWater Science and TechnologyCogenerationWaste managementbusiness.industryDesalinationParallel MEDSolar energyPollutionRenewable energyTRNSYS13. Climate actionbusinessEnergy sourceConcentrated solar powerModel
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L’inclusione vista dagli alunni: costruzione e validazione del questionario per rilevare la qualità inclusiva della scuola

2018

Molti studi nazionali e internazionali si sono concentrati sulla valutazione e sulla promozione della qualità inclusiva della scuola. Si tratta di un argomento complesso, che ha stimolato un ampio dibattito e una varietà di contributi che mettono in luce la necessità di uno strumento in grado di misurare la qualità inclusiva delle nostre scuole, per determinare l’evidenza empirica riguardo a questo tema. L’articolo presenta i risultati di una sperimentazione finalizzata alla redazione di un questionario per la rilevazione della qualità inclusiva del sistema scolastico percepita dagli alunni. Il questionario si pone come uno strumento di valutazione e autovalutazione che permette la misurazi…

Many national and international studies have concentrated on the evaluation and promotion of the inclusive qualities of schools. It is a complex issue which has led to wide debate and a variety of contributions which in turn highlight the need for a tool capable of measuring the inclusive quality of our schools in order to determine the empirical evidence regarding this topic. This article presents the results of an experiment in drafting a questionnaire in order to measure the inclusive quality of the school system perceived by its pupils. The questionnaire is intended as an evaluation and selfevaluation tool that enables the inclusive quality generated by the context to be measured as it is perceived by pupils. At the same time the tool allows reflection processes amongst teachers to be promoted so that they can implement educational activities which contribute to the planning and control of inclusive teaching practices. This contribution puts forward an original tool for measuring the inclusive quality of the school system perceived by pupils attending primary school in several Sicilian towns. It was administered in its definitive version to a sample of 1652 children. The psychometric properties of the tool and the significance it can hold in the areas of planning in research and of educational design are presented in this paper.Settore M-PED/03 - Didattica E Pedagogia Speciale
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Focal lesions of the Achilles tendon: real-time variation of lesion grading during ultrasound-guided platelet-concentrate injection.

2009

INTRODUCTION: Achillodynia (Achilles tendon pain) is a significant source of disability for many sport people. Achilles tendon (AT) tear is the third most frequent major tendon disruption after those of the rotator cuff and knee extensor mechanism. The incidence of the AT tears is 11–18% overall. Unlike acute AT tear, chronic tear diagnosis is more difficult to make particularly when the chronic tear involves the AT only partially. Over the last 10 years, real time ultrasound has been used increasingly to diagnose Achilles tendon tears, thanks to its ability to perform dynamic study, in passive and active muscle contraction. Furthermore, ultrasound-guided procedures are increasingly used fo…

ultrasound-guided injection platelet-concentrate Achilles tendon
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Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review.

2019

Abstract The objective of this scoping review is to summarize the current use of pharmacokinetics for tailoring prophylaxis in hemophilia patients switching between clotting factor products. Patients with hemophilia may require switching of clotting factor concentrates due to a variety of factors, but there have been perceived risks associated with switching, such as inhibitor development or suboptimal protection due to inadequate dosing while titrating treatment. Studies that look at patients switching from one clotting factor concentrate to another are categorized in terms of their primary and/or secondary objectives, notably biosimilarity and comparative pharmacokinetic studies and inhib…

medicine.medical_specialtyFactor concentrate610 Medicine & healthReview Article030204 cardiovascular system & hematologyHemophilia ADrug SubstitutionHemophilia BFactor IX03 medical and health sciencesDrug substitution0302 clinical medicinePharmacokineticsmedicineDosingIntensive care medicineFactor IXClotting factorOriginal Articles: Haemostasisfactor IXFactor VIIIlcsh:RC633-647.5business.industryDosing regimenlcsh:Diseases of the blood and blood-forming organsHematology3. Good healthOnline‐only Articlesfactor VIII3121 General medicine internal medicine and other clinical medicinedrug substitution10032 Clinic for Oncology and Hematologydrug substitution; factor IX; factor VIII; hemophilia A; hemophilia Bhemophilia Bhemophilia Abusiness030215 immunologymedicine.drug
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