Search results for "Concentration."
showing 10 items of 1849 documents
Identification of highly effective antitrypanosomal compounds in essential oils from the Apiaceae family
2018
The Apiaceae family encompasses aromatic plants of economic importance employed in foodstuffs, beverages, perfumery, pharmaceuticals and cosmetics. Apiaceae are rich sources of essential oils because of the wealth of secretory structures (ducts and vittae) they are endowed with. The Apiaceae essential oils are available on an industrial level because of the wide cultivation and disposability of the bulky material from which they are extracted as well as their relatively cheap price. In the fight against protozoal infections, essential oils may represent new therapeutic options. In the present work, we focused on a panel of nine Apiaceae species (Siler montamon, Sison amomum, Echinophora spi…
New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1,2,4-trioxane…
2015
Abstract In our ongoing search for highly active hybrid molecules exceeding their parent compounds in anticancer, antimalaria as well as antiviral activity and being an alternative to the standard drugs, we present the synthesis and biological investigations of 2nd generation 1,2,4-trioxane-ferrocene hybrids. In vitro tests against the CCRF-CEM leukemia cell line revealed di-1,2,4-trioxane-ferrocene hybrid 7 as the most active compound (IC50 of 0.01 μM). Regarding the activity against the multidrug resistant subline CEM/ADR5000, 1,2,4-trioxane-ferrocene hybrid 5 showed a remarkable activity (IC50 of 0.53 μM). Contrary to the antimalaria activity of hybrids 4–8 against Plasmodium falciparum …
Israel State, Genocide and Thana-Capitalism
2019
The term “genocide” was originally coined by Lemkin just after the horrendous crimes committed against innocent civilians in Nazi Germany. At that moment, the SS officials disposed of a systemic rationalized system of death which was oriented to domesticate and eradicate the “inferior” or the undesired “Other”. The concentration camps were space of torture, violence, death and mourning that marked the state of Israel forever. Today things have changed a lot, and the state of Israel is accused of violating the human rights in Palestine. While we review the discussion of senior lecturers such as Slavoj Žižek, Richard Bernstein, Norman Finkelstein and Yakov Rabkin, we reconstruct the philosoph…
Hydrogen-ion driven molecular motions in Cu2+-complexes of a ditopic phenanthrolinophane ligand
2004
One of the first kinetic evaluations of a metal ion interchange between the two coordination sites of a ditopic macrocycle is presented. Garcia-España Monsonis, Enrique, Enrique.Garcia-Es@uv.es ; Soriano Soto, Concepción, Concepcion.Soriano@uv.es ; Verdejo Viu, Begoña, Begona.Verdejo@uv.es
MANUAL SAMPLING AND TANK SIZE EFFECTS ON THE CALIBRATION CURVE OF PLOT SEDIMENT STORAGE TANKS
2004
In many experimental soil erosion plots, runoff is collected and carried by a conveyance system to a sequence of storage tanks. If the soil loss is measured by collecting, after mixing, samples of the stored suspension, then a calibration curve between the actual mean concentration (C) and the measured concentration (Cm) in the storage tank occurs. The aim of this article was to evaluate experimentally the factors affecting the relationship between C and Cm. For a sandy loam soil, the replicated measurements of Cm (20 samples) for two values of the actual concentration (C = 5 and 25 g/L) showed that the variability of the measurements of Cm is low and confirmed the reliability of a calibrat…
Overland Flow Times of Concentration for Hillslopes of Complex Topography
2016
The time of concentration is an important parameter for predicting peak discharge at the basin outlet and for designing urban infrastructure facilities. In studying the hillslope response, employing hydraulic equations of flow, the shape of the hillslope geometry has often been assumed as rectangular and planar. However, natural hillslopes have complex topographies whose shapes are characterized by irregularly spaced contour lines. Recently, kinematic wave time of concentration has been derived for rectangular and curved parallel hillslopes. This paper extends this work to hillslopes of complex planform geometry, considering the degree of divergence or convergence of the hillslope. The exte…
Effect of plot size on measured soil loss for two Italian experimental sites
2011
The objective of this investigation was to determine empirically the plot width and length effects on runoff volume, Ve, soil loss, Ae, and sediment concentration, Ce, by using data collected, at the temporal scale of the erosive event, on bare plots differing in width (2 to 8 m) and length (11 to 22 m) for two Italian stations (Masse, Umbria; Sparacia, Sicily). Mean results differed by a maximum factor of 1.6 for Ve, 1.8 for Ae and 1.2 for Ce when plots differing in width were compared and by a maximum factor of 1.4 for Ve, 1.2 for Ae and 1.3 for Ce when comparison between plot lengths was conducted. Differences between two plot widths or two plot lengths were not statistically significant…
Characterization of a new, nonpathogenic mutant of Botrytis cinerea with impaired plant colonization capacity.
2006
International audience; Botrytis cinerea is a necrotrophic pathogen that attacks more than 200 plant species.Here, the nonpathogenic mutant A336, obtained via insertional mutagenesis, was characterized.Mutant A336 was nonpathogenic on leaves and fruits, on intact and wounded tissue, while still able to penetrate the host plant. It grew normally in vitro on rich media but its conidiation pattern was altered. The mutant did not produce oxalic acid and exhibited a modified regulation of the production of some secreted proteins (acid protease 1 and endopolygalacturonase 1). Culture filtrates of the mutant triggered an important oxidative burst in grapevine ( Vitis vinifera ) suspension cells, a…
Tissue invasiveness and non-acidic pH in human candidiasis correlate with "in vivo" expression by Candida albicans of the carbohydrate epitope recogn…
2004
Background: The morphogenetic conversion between yeast and hyphal growth forms appears to be crucial in the pathogenesis of invasive candidiasis, and can be regulated by environmental signals such as extracellular pH. Aims: To characterise the epitope recognised by monoclonal antibody 1H4, and to evaluate the expression of its corresponding epitope in Candida albicans cells under different conditions of pH and temperature, and “in vivo”, in tissue samples from patients with human candidiasis. Methods: Monoclonal antibody 1H4 was generated against the 58 kDa cell wall mannoprotein of C albicans (mp58), and was further characterised by immunoblot analysis, periodate treatment of the antigenic…
INCREASED MACROPHAGE COLONY STIMULATING FACTOR CONCENTRATIONS ARE ASSOCIATED WITH LEFT VENTRICLE SYSTOLIC DYSFUNCTION IN PATIENTS WITH ACUTE CORONARY…
2007
INCREASED MACROPHAGE COLONY STIMULATING FACTOR CONCENTRATIONS ARE ASSOCIATED WITH LEFT VENTRICLE SYSTOLIC DYSFUNCTION IN PATIENTS WITH ACUTE CORONARY SYNDROMES