Search results for "Condensate"
showing 10 items of 208 documents
Environment Exposure to Pollutants
2015
Effects of exposure to welding fume on lung function: results from the German WELDOX study. M. Lehnert, F. Hoffmeyer, K. Gawrych, A. Lotz, E. Heinze, H. Berresheim, R. Merget, V. Harth, R. Van Gelder, J.-U. Hahn, A. Hartwig, T. Weiss, B. Pesch, and T. Bruning, for the WELDOX Study Group Disability-Adjusted Life Years in the Assessment of Health Effects of Traffic-Related Air Pollution. L. Adamkiewicz, A.J. Badyda, A. Gayer, and D. Mucha Impact of Traffic-Related Air Pollution on Health. J. Jakubiak-Lasocka, J. Lasocki, R. Siekmeier, and Z. Chlopek Traffic-related air pollution and respiratory tract efficiency. A.J. Badyda, P. Dabrowiecki, P.O. Czechowski, G. Majewski, and A. Doboszynska Dif…
Use of a running coupling in the NLO calculation of forward hadron production
2018
We address and solve a puzzle raised by a recent calculation [1] of the cross-section for particle production in proton-nucleus collisions to next-to-leading order: the numerical results show an un- reasonably large dependence upon the choice of a prescription for the QCD running coupling, which spoils the predictive power of the calculation. Specifically, the results obtained with a prescription formulated in the transverse coordinate space differ by one to two orders of magnitude from those obtained with a prescription in momentum space. We show that this discrepancy is an artefact of the interplay between the asymptotic freedom of QCD and the Fourier transform from coordinate space to mo…
Dual film-like organelles enable spatial separation of orthogonal eukaryotic translation
2021
Summary Engineering new functionality into living eukaryotic systems by enzyme evolution or de novo protein design is a formidable challenge. Cells do not rely exclusively on DNA-based evolution to generate new functionality but often utilize membrane encapsulation or formation of membraneless organelles to separate distinct molecular processes that execute complex operations. Applying this principle and the concept of two-dimensional phase separation, we develop film-like synthetic organelles that support protein translation on the surfaces of various cellular membranes. These sub-resolution synthetic films provide a path to make functionally distinct enzymes within the same cell. We use t…
Oxidative lung injury correlates with one-lung ventilation time during pulmonary lobectomy: a study of exhaled breath condensate and blood.
2015
OBJECTIVES: During lung lobectomy, the operated lung is collapsed and hypoperfused; oxygen deprivation is accompanied by reactive hypoxic pulmonary vasoconstriction. After lung lobectomy, ischaemia present in the collapsed state is followed by expansion–reperfusion and lung injury attributed to the production of reactive oxygen species. The primary objective of this study was to investigate the time course of several markers of oxidative stress simultaneously in exhaled breath condensate and blood and to determine the relationship between oxidative stress and one-lung ventilation time in patients undergoing lung lobectomy. METHODS: This single-centre, observational, prospective study includ…
Effects of cigarette smoke on methacholine- and AMP-induced air trapping in asthmatics.
2014
Abstract Objective: No information is available on the effect of cigarette smoke on bronchoconstrictor-induced air trapping in asthma. The aim of this study was to evaluate the additional influence of smoking on methacholine- and adenosine 5'-monophosphate (AMP)-induced air trapping in subjects with asthma.Airway responsiveness to methacholine and AMP, bronchial (J'awNO) and alveolar (CANO) nitric oxide (NO) and exhaled breath condensate pH were measured in 68 adults (23 current smokers with asthma, 23 non-smokers with asthma and 22 current or former smokers with chronic obstructive pulmonary disease; COPD). The degree of air trapping induced by each bronchoconstrictor agent was expressed b…
The effect of different periods of argon deaeration on exhaled breath condensate pH.
2011
Exhaled breath condensate (EBC) pH has been considered as a biomarker of airway inflammation in asthma. However, little information is available on the duration of argon deaeration required to achieve a stable pH in EBC samples.To identify differences in EBC pH after argon deaeration for 2, 4, and 8 min.EBC pH was determined in EBC samples from 48 subjects with allergic rhinitis (11 asthmatics) and 14 healthy volunteers without deaeration and after argon deaeration for 2, 4, and 8 min.The mean (95% CI) pH values obtained from samples analyzed after 4 min [7.66 (7.52-7.80)] and 8 min [7.70 (7.55-7.85)] of argon deaeration were significantly less acidic (p.001) than those identified after 2 m…
Small airways function and molecular markers in exhaled air in mild asthma.
2005
Background: Several studies suggest that the periphery of the lung is the major site of inflammation in asthma. Fractional exhaled nitric oxide (FeNO) and 8-isoprostane have been proposed as biomarkers of inflammation and oxidative stress. We therefore hypothesised that small airway dysfunction in asthma is of inflammatory origin that can be detected by molecular markers in exhaled air. To test this hypothesis, we examined the relationship of FeNO and 8-isoprostane in exhaled air with small airways function as assessed by the single breath nitrogen test. Methods: Sixteen patients (14 women) with mild atopic asthma (forced expiratory volume in 1 second >80% predicted) of mean (SD) age 23.0 (…
Maximal Response Plateau to Adenosine 5′-Monophosphate in Asthma
2009
Background No information is available on the plateau in response to adenosine 5′-monophosphate. The aims of the present study were to determine whether plateau can be detected with AMP and the relation with the plateau in response to methacholine, and to identify the relation between the plateau and indirect markers of airway inflammation, such as exhaled nitric oxide (ENO) and exhaled breath condensate (EBC) pH. Methods Airway responsiveness to high concentrations of methacholine and AMP, ENO levels, and EBC pH values were obtained in 31 subjects with well-controlled asthma. Concentration-response curves were characterized by their concentration of agonist that produces a decrease in FEV …
Room-temperature polariton luminescence from a bulk GaN microcavity
2006
We report strong exciton-photon coupling at room temperature in a hybrid high quality bulk 3 lambda/2 GaN cavity with a bottom lattice-matched AlInN/AlGaN distributed Bragg reflector through angle-resolved polarized photoluminescence (PL). Coupling of the optically active free excitons (X-A, X-B, and X-C) to the cavity mode is demonstrated, with their contribution to the PL spectra varying with polarization. Under TE polarization, exciton oscillator strengths for X-A and X-B are about one order of magnitude larger than in bulk GaAs. Photoluminescence exhibits a strong bottleneck effect despite its thermal lineshape.
Production of inclusive ϒ(1S) and ϒ(2S) in p–Pb collisions at sNN=5.02 TeV
2015
We report on the production of inclusive Y{hooktop}(1S) and Y{hooktop}(2S) in p-Pb collisions at √sNN=5.02 TeV at the LHC. The measurement is performed with the ALICE detector at backward (-4.46<ycms<-2.96) and forward (2.03<ycms<3.53) rapidity down to zero transverse momentum. The production cross sections of the Y{hooktop}(1S) and Y{hooktop}(2S) are presented, as well as the nuclear modification factor and the ratio of the forward to backward yields of Y{hooktop}(1S). A suppression of the inclusive Y{hooktop}(1S) yield in p-Pb collisions with respect to the yield from pp collisions scaled by the number of binary nucleon-nucleon collisions is observed at forward rapidity but not at backwar…