Search results for "Conditional"

Data from: Intralocus tactical conflict: genetic correlations between fighters and sneakers of the dung beetle Onthophagus taurus

2015

Males and females differ in their phenotypic optima for many traits, and since the majority of genes are expressed in both sexes, some alleles can be beneficial to one sex but harmful to the other (intralocus sexual conflict; ISC). ISC theory has recently been extended to intrasexual dimorphisms, where certain alleles may have opposite effects on the fitness of males of different morphs that employ alternative reproductive tactics (intralocus tactical conflict; ITC). Here we use a half-sib breeding design to investigate the genetic basis for ISC and ITC in the dung beetle Onthophagus taurus. We found positive heritabilities and intersexual genetic correlations for almost all traits investig…

Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial

2021

The increased prevalence of atrial fibrillation (AF) and heart failure (HF) highlights the need to better understand the mechanisms underlying these cardiovascular diseases (CVDs). In the present study, we aimed to evaluate the association between glycolysis-related metabolites and the risk of AF and HF in a Mediterranean population at high risk of CVD. We used two case-control studies nested within the PREDIMED trial. A total of 512 incident AF cases matched to 734 controls, and 334 incident HF cases matched to 508 controls, were included. Plasma metabolites were quantified by using hydrophilic interaction liquid chromatography coupled with high-resolution negative ion mode MS detection. C…

Information domain approach to the investigation of cardio-vascular, cardio-pulmonary, and vasculo-pulmonary causal couplings

2011

The physiological mechanisms related to cardio-vascular (CV), cardio-pulmonary (CP), and vasculo-pulmonary (VP) regulation may be probed through multivariate time series analysis tools. This study applied an information domain approach for the evaluation of non-linear causality to the beat-to-beat variability series of heart period (t), systolic arterial pressure (s), and respiration (r) measured during tilt testing and paced breathing (PB) protocols. The approach quantifies the causal coupling from the series i to the series j (C(ij)) as the amount of information flowing from i to j. A measure of directionality is also obtained as the difference between two reciprocal causal couplings (D(i…

Conditional predictive inference for online surveillance of spatial disease incidence

2011

This paper deals with the development of statistical methodology for timely detection of incident disease clusters in space and time. The increasing availability of data on both the time and the location of events enables the construction of multivariate surveillance techniques, which may enhance the ability to detect localized clusters of disease relative to the surveillance of the overall count of disease cases across the entire study region. We introduce the surveillance conditional predictive ordinate as a general Bayesian model-based surveillance technique that allows us to detect small areas of increased disease incidence when spatial data are available. To address the problem of mult…

Factor selection procedures in a Google Earthtm aided landslide susceptibility model: application to the Beiro river basin (Spain)

2011

A procedure to select the controlling factors connected to the slope instability has been defined. It allowed to assess the landslide susceptibility in the Rio Beiro basin (about 10 km2) over the north-eastern area of the city of Granada (Spain). Field and remote (Google EarthTM) recognition techniques allowed to generate a landslide inventory consisting in 127 phenomena. Univariate tests, using both association coefficients and validation results of single parameter susceptibility models, allowed to select among 15 controlling factors the ones that resulted as good predictor variables; these have been combined for unique conditions analysis and susceptibility maps were finally prepared. In…

Configural learning in rabbit nictitating membrane conditioning : acquisition of biconditional discrimination

2004

Wiener-Granger Causality in Network Physiology with Applications to Cardiovascular Control and Neuroscience

2016

Since the operative definition given by C. W. J. Granger of an idea expressed by N. Wiener, the Wiener–Granger causality (WGC) has been one of the most relevant concepts exploited by modern time series analysis. Indeed, in networks formed by multiple components, working according to the notion of segregation and interacting with each other according to the principle of integration, inferring causality has opened a window on the effective connectivity of the network and has linked experimental evidences to functions and mechanisms. This tutorial reviews predictability improvement, information-based and frequency domain methods for inferring WGC among physiological processes from multivariate…

On the quantitative edge of feature and gestalt -based associative learning : learning-related ERP changes in the hippocampus and the prefontal corte…

2004

Economic studies on higher education and productivity

2015

Explaining local governments' cost efficiency: Controllable and uncontrollable factors

2020

Abstract Efficient and effective management of public resources is essential at all levels of government. This issue has gained momentum due to the strains that affected public sector finances after the onset of the 2007/08 crisis in many countries, particularly in Europe. In this article, we evaluate the influence of environmental variables that affect local government efficiency in one European country, Spain, during the crisis years (2009–2015). To this end, and considering the possible influence of both controllable and uncontrollable factors, we use an approach that is able to analyse their impact across the conditional distribution of performance, and which controls for the (likely) e…