Search results for "Constructive"
showing 10 items of 301 documents
Analysis of hybrid vehicle transmissions with any number of modes and planetary gearing: kinematics, power flows, mechanical power losses
2021
Abstract This paper is focused on upgrading a unified parametric model, available in the literature, that can perform both the analysis and the design of Power-Split Continuously Variable Transmissions (PS-CVTs), which are particularly promising to deploy in the hybrid electric powertrain. In particular, this work is focused on the analysis of PS-CVTs and proposes a new matrix approach for identifying the basic functional parameters underlying the model from the constructive layout of the transmission. This new method does not rely on a case-specific formulation, thus befits any power-split transmission, regardless of the number of planetary and ordinary gear sets and their constructive arr…
SLC20A1 Is Involved in Urinary Tract and Urorectal Development
2020
Previous studies in developing Xenopus and zebrafish reported that the phosphate transporter slc20a1a is expressed in pronephric kidneys. The recent identification of SLC20A1 as a monoallelic candidate gene for cloacal exstrophy further suggests its involvement in the urinary tract and urorectal development. However, little is known of the functional role of SLC20A1 in urinary tract development. Here, we investigated this using morpholino oligonucleotide knockdown of the zebrafish ortholog slc20a1a. This caused kidney cysts and malformations of the cloaca. Moreover, in morphants we demonstrated dysfunctional voiding and hindgut opening defects mimicking imperforate anus in human cloacal exs…
Macrophage type modulates osteogenic differentiation of adipose tissue MSCs
2017
Since the reconstruction of large bone defects remains a challenge, knowledge about the biology of bone healing is desirable to develop novel strategies for improving the treatment of bone defects. In osteoimmunology, macrophages are the central component in the early stage of physiological response after bone injury and bone remodeling in the late stage. During this process, a switch of macrophage phenotype from pro-inflammatory (M1) to anti-inflammatory (M2) is observed. An appealing option for bone regeneration would be to exploit this regulatory role for the benefit of osteogenic differentiation of osteoprogenitor cells (e.g., mesenchymal stem cells; MSCs) and to eventually utilize this…
Addressing ecological effects of radiation on populations and ecosystems to improve protection of the environment against radiation: Agreed statement…
2016
AbstractThis paper reports the output of a consensus symposium organized by the International Union of Radioecology in November 2015. The symposium gathered an academically diverse group of 30 scientists to consider the still debated ecological impact of radiation on populations and ecosystems. Stimulated by the Chernobyl and Fukushima disasters' accidental contamination of the environment, there is increasing interest in developing environmental radiation protection frameworks. Scientific research conducted in a variety of laboratory and field settings has improved our knowledge of the effects of ionizing radiation on the environment. However, the results from such studies sometimes appear…
ISL1 is a major susceptibility gene for classic bladder exstrophy and a regulator of urinary tract development
2017
AbstractPreviously genome-wide association methods in patients with classic bladder exstrophy (CBE) found association with ISL1, a master control gene expressed in pericloacal mesenchyme. This study sought to further explore the genetics in a larger set of patients following-up on the most promising genomic regions previously reported. Genotypes of 12 markers obtained from 268 CBE patients of Australian, British, German Italian, Spanish and Swedish origin and 1,354 ethnically matched controls and from 92 CBE case-parent trios from North America were analysed. Only marker rs6874700 at the ISL1 locus showed association (p = 2.22 × 10−08). A meta-analysis of rs6874700 of our previous and prese…
The role of music in adolescents' mood regulation
2007
The aim of this study was the exploration and theoretical clarification of the role of music in adolescents' mood regulation. The phenomenon was approached through an inductive theory construction. The data were gathered from eight adolescents by means of group interviews and follow-up forms, and were then analysed using constructive grounded theory methods. The analysis resulted in a theoretical model, which describes mood regulation by music as a process of satisfying personal mood-related goals through various musical activities. The general nature of the mood regulation is described, the goals and strategies of mood regulation are examined, and finally the specific role of music in moo…
China in Pakistan and the wider region: A cautious but effective leader?
2018
This article assesses China–Pakistan-Afghanistan relations in the period 2014–2018 and asks whether China has exercised distinct pressure on Pakistan to be a more constructive partner for Afghanistan. A central argument is that even as China has failed to alter Pakistan’s policies significantly in the short term it is still continuing to successfully build power and trust in Pakistan and Afghanistan, as well as with their neighbours to the north and west. This bodes well for China’s exercise of regional leadership in a long-term perspective.
4-5 gadu vecu bērnu ģeometrisko priekšstatu veidošanās konstruktīvajās rotaļās
2019
Pētījuma nosaukums:4-5 gadu vecu bērnu ģeometrisko priekšstatu veidošanās konstruktīvajās rotaļās. Mērķis: Izpētīt 4-5 gadu vecu bērnu ģeometrisko priekšstatu veidošanos konstruktīvajās rotaļās. Diplomdarbs sastāv no ievada, piecām nodaļām, nobeiguma, izmantotās literatūras saraksts ar 65 vienībām un 12 pielikumiem. Darba apjoms 45 lappuses Pirmajā nodaļā analizēts ģeometrisko priekšstatu veidošanās. Otrajā nodaļā analizētas konstruktīvās rotaļas. Trešajā nodaļā 4-5 gadu vecu bērnu vecumposma raksturojums. Ceturtajā nodaļā analizēta ģeometrisko priekšstatu veidošanās konstruktīvajās rotaļās pedagoģiskā pieredze. Piektajā nodaļā aprakstīta 4-5 gadu vecu bērnu ģeometrisko priekšstatu veidošan…
Case study on teachers’ contribution to children’s participation in Finnish preschool classrooms during structured learning sessions
2013
The main aim of this study was to identify different teaching practices and explore the types of opportunities that they provide for children’s participation in four different Finnish preschool classrooms for 6-year olds during structured learning sessions. Observational data of four preschool teachers were analyzed according to the principles of qualitative content analysis. Three themes of teachers’ practices were identified, which described the key practices through which teachers influence children’s participation, namely, through discussion and conversations; by referring to shared rules and managing the classroom; and through demonstrating pedagogical sensitivity and understanding tow…
Genesi geometrica delle volte centriche
1996
Un'analisi completa degli organismi voltati comporta lo studio delle molteplici componenti necessarie alla loro definizione: configurazione geometrica, sistema costruttivo, area storico-geografica di appartenenza, interpretazioni Stilistiche. L’obiettivo di questo studio è indirizzato all' analisi delle volte continue su pianta centrica definibili attraverso le leggi della geometria euclidea. L’indagine si pone all'interno dei confini relativi alla loro configurazione geometrica e il criterio adottato, svincolato da classificazioni di carattere tipologico o stilistico, propone l'identificazione di famiglie geometriche in base alla figura del poligono di base dell'impianto. Si può identifica…