Search results for "Control"

showing 10 items of 13168 documents

Teprotumumab for patients with active thyroid eye disease: a pooled data analysis, subgroup analyses, and off-treatment follow-up results from two ra…

2020

Thyroid eye disease manifests inflammation and treatment-resistant proptosis and diplopia. Teprotumumab, an insulin-like growth factor-1 receptor inhibiting monoclonal antibody, was approved in the USA on Jan 21, 2020, on the basis of two randomised trials. In this analysis we evaluated the short-term and long-term aggregate response to teprotumumab from the two trials, focusing on proptosis and diplopia.We analysed integrated outcomes and follow-up data from two randomised, double-masked, placebo-controlled, multicentre, trials done at a total of 28 academic referral tertiary specialised centres offering joint thyroid eye clinics, or orbital clinics or practices, or both, in Europe and the…

AdultData AnalysisMalemedicine.medical_specialtyEndocrinology Diabetes and MetabolismEye diseasePopulation030209 endocrinology & metabolismAntibodies Monoclonal HumanizedPlaceboSeverity of Illness Indexlaw.inventionPlacebos03 medical and health sciences0302 clinical medicineEndocrinologyDouble-Blind MethodRandomized controlled triallawInternal medicineSeverity of illnessInternal MedicinemedicineHumans030212 general & internal medicineeducationAgedDiplopiaeducation.field_of_studybusiness.industryThyroidMiddle Agedmedicine.diseaseUnited Stateseye diseasesEuropeGraves OphthalmopathyTreatment Outcomemedicine.anatomical_structureFemalemedicine.symptombusinessOff TreatmentFollow-Up StudiesThe Lancet Diabetes & Endocrinology
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Effect of undersized drilling on the stability of immediate tapered implants in the anterior maxillary sector. A randomized clinical trial.

2020

Background To evaluate the effect of undersized drilling on the primary and secondary stability of immediate implants placed in the anterior maxilla. Material and Methods A comparative randomized clinical trial was carried out in 30 healthy adults. Thirty tapered implants, 16 involving conventional drilling and 14 undersized drilling, were placed immediately after anterior maxillary tooth removal. Insertion torque and implant stability assessed by resonance frequency analysis (RFA) were evaluated at three different timepoints: at implant placement and 6 and 12 weeks post-implantation. The results were compared using parametric statistical tests. Results All implants showed adequate stabilit…

AdultDentistryOsseointegrationMaxillary toothlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawBone DensityOsseointegrationosteoradionecrosisMaxillaMedicineHumansradiotherapy bone necrosisGeneral DentistryUNESCO:CIENCIAS MÉDICASteriparatideDental Implantsbusiness.industryResearchDental Implantation EndosseousResonance Frequency AnalysisDrilling030206 dentistrylow level laser therapyImplant placementResonance frequency analysispentoxifyllineOtorhinolaryngologyTorquehyperbaric oxygenMaxillaSurgeryImplantbusinessImplantologyMedicina oral, patologia oral y cirugia bucal
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Influence of family history of NIDDM on basal metabolic rate in sedentary and active women

2011

Aim and methods: The influence of family history of non-insulin-dependent diabetes (NIDDM) on basal metabolic rate (BMR) has been investigated in 116 voluntarily women: 25 sedentary and 34 athletes without a family predisposition to type 2 diabetes (FH-); 21 sedentary and 15 athletes with a second degree predisposition to NIDDM (FH +); 10 sedentary and 11 athletes with a first degree predisposition to NIDDM (FH ++). Results: The results showed that family history on type 2 diabetes is strongly related to sedentary in women with significant high body weight values and an increased fat mass. There was no significant difference in the body parameters among the athletes groups, confirming the p…

AdultDiabetes Mellitus Type 2Case-Control StudiesBody CompositionHumansFemaleBasal MetabolismExerciseBody composition Diabetes mellitus Energy metabolism Epidemiology Motor activity Risk factors Type 2
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Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes

2019

Background The stems of Opuntia ficus-indica, known as cladodes, are a rich source of soluble fibers, which makes them an important candidate for the production of functional foods. Tagliatelle of durum wheat fortified with Opuntia cladode extract (OCE) at different levels of addition (10-30%, v/w) was prepared on a laboratory scale and quality characteristics and sensory acceptability were assessed. Results The main quality parameters (optimal cooking time, swelling index, cooking loss, dry matter) and sensory analysis on a nine-point hedonic scale were comparable with those of the control pasta sample (no added OCE) when durum wheat was supplemented with OCE at up to 20% (v/w). An in vitr…

AdultDietary FiberMaleQuality Controlin vitro digestion030309 nutrition & dieteticsOpuntia ficusStarch digestionSensory analysisGastrointestinal digestionfunctional foodYoung Adult03 medical and health sciences0404 agricultural biotechnologysterols bioaccesibilityOpuntia cladode extract; functional food; in vitro digestion; sterols bioaccesibilitySettore BIO/10 - BiochimicaCladodesHumansDry matterCookingFood scienceQuality characteristicsTriticumAgedOpuntia cladode extract0303 health sciencesNutrition and DieteticsbiologyPlant ExtractsChemistryOpuntiafood and beverages04 agricultural and veterinary sciencesMiddle Agedbiology.organism_classification040401 food scienceSettore CHIM/08 - Chimica FarmaceuticaGastrointestinal TractTasteFood FortifiedBlood cholesterolDigestionFemaleAgronomy and Crop ScienceFood ScienceBiotechnology
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Strategic responses to intimate partner violence against women in Spain: a national study in primary care

2012

Background Research on women99s responses to intimate partner violence (IPV) has largely been limited to women who have been exposed to severe physical violence with scarce generalisation. This study aimed to analyse how Spanish abused women from different backgrounds and with different IPV characteristics respond to violence. Method Women experiencing IPV before the previous year (1469) were selected from a large cross-sectional national survey of adult women recruited during 2006–7 among female patients seeking medical care for whatever reason in primary healthcare services. The outcome variables were women9s responses to IPV and the predictor variables were personal and social resources …

AdultDomestic ViolenceEpidemiologyDistancingeducationPsychological interventionPoison controlSuicide preventionbehavioral disciplines and activitiesOccupational safety and healthPregnancySurveys and QuestionnairesInjury preventionmental disordersHumansMedicineDones Salut i higienePsychological abuseFamily CharacteristicsPrimary Health Carebusiness.industryBattered WomenPublic Health Environmental and Occupational Healthsocial sciencesMiddle AgedPatient Acceptance of Health CareSelf ConceptCross-Sectional StudiesLogistic ModelsMental HealthSexual PartnersSocioeconomic FactorsSpainWomen's HealthDomestic violenceDones Delictes contraFemaleHealth Services ResearchbusinessClinical psychology
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Perceived Frequency of Domestic Violence against Women and Neighbourhood Social Disorder

2005

Regression analyses from a nationally representative sample of 10,235 adult Spaniards, provided in 1995 from the Spanish Demands of Security and Victimization Survey, showed a small and positive relationship between high neighbourhood social disorder and perceived frequency of domestic violence against women in Spanish families, after controlling for sociodemographic variables and size of city. Among sociodemographic variables, sex had the strongest association with neighbourhood social disorder, being more than twice as large as neighbourhood social disorder.

AdultDomestic ViolencePeriodicityAdolescenteducationPoison control050109 social psychologySuicide preventionOccupational safety and healthSocial disorder0504 sociologyResidence CharacteristicsEnvironmental healthInjury preventionHumans0501 psychology and cognitive sciencesNeighbourhood (mathematics)General PsychologyAged05 social sciencesSocial Behavior Disorders050401 social sciences methodsHuman factors and ergonomicssocial sciencesMiddle AgedAttitudeDomestic violenceFemalePsychologyPsychological Reports
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The Assessment of Intimate Partner Violence in Spanish Women

2011

We aimed to analyze the internal consistency and construct validity of the Spanish version of the Index of Spouse Abuse (ISA) in a representative sample of 8,995 women attending general practice in Spain in 2006-2007. The factor structure analysis shows that the ISA measures four intimate partner violence (IPV) dimensions: emotional, physical, and sexual abuse, and controlling behavior. Cronbach alpha ranges from .82 (sexual factor) to .94 (emotional). Construct validity analysis shows that IPV is associated with poorer self-perceived health, higher psychological distress, and lower tangible social support. The ISA can help make more visible forms of gender violence in the intimate relatio…

AdultDomestic ViolenceSexual violenceAdolescentBattered WomenHealth StatusConstruct validityPoison controlMiddle AgedYoung AdultClinical PsychologySocial supportCross-Sectional StudiesCronbach's alphaSexual abuseSpainSpouseSurveys and QuestionnairesHumansDomestic violenceFemalePsychologyApplied PsychologyAgedClinical psychologyJournal of Interpersonal Violence
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Changes in cortisol and dehydroepiandrosterone in women victims of physical and psychological intimate partner violence

2003

Background Although intimate partner violence (IPV) has a great impact on women's health, few studies have assessed the consequences on physiologic responses. Methods Women abused by their intimate male partners either physically (n = 70) or psychologically (n = 46) were compared with nonabused control women (n = 46). Information about sociodemographic characteristics, smoking, pharmacologic treatment, lifetime history of victimization (childhood and adulthood), and mental health status (depression, anxiety, and posttraumatic stress disorder, PTSD) was obtained through structured interviews. Saliva samples were collected at 8 am and 8 pm for 4 consecutive days to determine morning and eveni…

AdultDomestic Violencemedicine.medical_specialtyTime FactorsEveningHydrocortisoneVictimologyPoison controlEnzyme-Linked Immunosorbent AssayAnxietyNeuropsychological TestsStress Disorders Post-TraumaticmedicineHumansSalivaPsychiatryCrime VictimsBiological PsychiatryMorningAnalysis of VarianceDepressionBattered WomenDehydroepiandrosteronesocial sciencesMiddle Agedmedicine.diseaseMental healthAnxietyDomestic violenceFemalemedicine.symptomPsychologyAnxiety disorderBiological Psychiatry
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Teachers bullied by students: forms of bullying and perpetrator characteristics.

2012

The focus of this study is on the forms in which the bullying of school teachers by students manifests itself, the characteristics of the students who engage in the bullying, and the manner in which the students who engage in bullying behave in their own peer relationships. The data was gathered from primary and lower secondary school teachers by means of an Internet survey. The answers of 70 teachers who had experienced bullying by their students are examined.The teachers had been exposed to different forms of bullying by students. They had typically been bullied by male students. In most cases, the bullying had been perpetrated by an individual student or a small group of students. Accord…

AdultDominance-SubordinationMaleHealth (social science)Injury controlAdolescentPoison controlPeer relationshipsSocial EnvironmentSuicide preventionOccupational safety and healthPathology and Forensic MedicineDevelopmental psychologySchool teachersPedagogyInjury preventionMedicineHumansInterpersonal RelationsChildCrime VictimsFinlandInternetSchoolsbusiness.industryHuman factors and ergonomicsBullyingGeneral MedicineMiddle AgedFacultyAggressionFemalebusinessLawViolence and victims
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First-trimester screening for trisomy-21 using a simplified method to assess the presence or absence of the fetal nasal bone.

2005

Objective To determine the benefit of including nasal bone assessment in addition to standard first-trimester markers (nuchal translucency, free beta human chorionic gonadotropin and pregnancy-associated plasma protein A) as a screening test for Down syndrome, using a strict criterion for classification of nasal bone absence. Study design Nasal bone assessment was conducted in 2411 patients with crown-rump length between 45 and 84 mm, including 15 patients with Down syndrome. A patient was considered to have an absent nasal bone only if there was no evidence of present nasal bone. Unlike other studies, nasal bone was classified as present when there was evidence of a thin echogenic line und…

AdultDown syndromemedicine.medical_specialtyPregnancy-associated plasma protein AUrologyAneuploidyPrenatal diagnosisEmbryonic StructuresSensitivity and SpecificityCrown-Rump LengthUltrasonography PrenatalPredictive Value of TestsPregnancyReference ValuesRisk FactorsmedicineConfidence IntervalsHumansMass ScreeningNasal BoneProbabilityObstetricsbusiness.industryObstetrics and GynecologyEchogenicityPrenatal Caremedicine.diseaseNasal boneConfidence intervalPregnancy Trimester FirstCase-Control StudiesLinear ModelsFemaleDown SyndromeTrisomybusinessNuchal Translucency MeasurementAmerican journal of obstetrics and gynecology
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