Search results for "Core"

showing 10 items of 1999 documents

Interplays Between Corporate Reputation And Media – A Bibliometric Analysis

2020

Abstract As strategic asset – determinant of sustained competitiveness – corporate/firm reputation has a very distinctive feature that sets it apart: although reflection of (better, worse or not at all performed) reputation management at a company’s level, it is rather a “representation” / “perception” – built on a business’s previous behaviors, but more precisely on the ways its different stakeholders have interacted (acknowledged, internalized, resonated) with them – in a (sometimes unconscious) process highly mediated and moderated by the media. Thus, the current study aims to explore the interplays between corporate/firm reputation and media as they are reflected in the scientific liter…

Bibliometric analysisSocial PsychologyvosviewerHF5001-6182business.industry05 social sciencesEconomics Econometrics and Finance (miscellaneous)mediaAccountingCorporate reputationwos core collectionbibliometric analysis0502 economics and businessBusiness Management and Accounting (miscellaneous)050211 marketingBusinessBusinesscorporate/firm reputation050203 business & managementStudies in Business and Economics
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Radiomics and Prostate MRI: Current Role and Future Applications

2021

Multiparametric prostate magnetic resonance imaging (mpMRI) is widely used as a triage test for men at a risk of prostate cancer. However, the traditional role of mpMRI was confined to prostate cancer staging. Radiomics is the quantitative extraction and analysis of minable data from medical images; it is emerging as a promising tool to detect and categorize prostate lesions. In this paper we review the role of radiomics applied to prostate mpMRI in detection and localization of prostate cancer, prediction of Gleason score and PI-RADS classification, prediction of extracapsular extension and of biochemical recurrence. We also provide a future perspective of artificial intelligence (machine …

Biochemical recurrencemedicine.medical_specialtyReviewlcsh:Computer applications to medicine. Medical informaticslcsh:QA75.5-76.95030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancer0302 clinical medicineRadiomicsProstatelocalmedicineRadiology Nuclear Medicine and imaginglcsh:PhotographyGleason scoreElectrical and Electronic EngineeringMultiparametric Magnetic Resonance ImagingFuture perspectivemedicine.diagnostic_testbusiness.industryMagnetic resonance imaginglcsh:TR1-1050prostate cancerartificial intelligencemultiparametric magnetic resonance imagingneoplasm recurrencemedicine.diseaseComputer Graphics and Computer-Aided Designprostate cancer; artificial intelligence; multiparametric magnetic resonance imaging; Gleason score; neoplasm recurrence; localmedicine.anatomical_structure030220 oncology & carcinogenesislcsh:R858-859.7lcsh:Electronic computers. Computer scienceComputer Vision and Pattern RecognitionRadiologyProstate cancer stagingbusiness
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Effect of endothelial cell heterogeneity on nanoparticle uptake.

2020

Endothelial cells exhibit distinct properties in morphology and functions in different organs that can be exploited for nanomedicine targeting. In this work, endothelial cells from different organs, i.e. brain, lung, liver, and kidney, were exposed to plain, carboxylated, and amino-modified silica. As expected, different protein coronas were formed on the different nanoparticle types and these changed when foetal bovine serum (FBS) or human serum were used. Uptake efficiencies differed strongly in the different endothelia, confirming that the cells retained some of their organ-specific differences. However, all endothelia showed higher uptake for the amino-modified silica in FBS, but, inter…

Biodistributionmedia_common.quotation_subjectReceptor expressionEndothelial cellsBristol Heart InstitutePharmaceutical ScienceUptake02 engineering and technologyADHESIONBlood–brain barrier030226 pharmacology & pharmacySERUM03 medical and health sciencesDELIVERY0302 clinical medicineBIODISTRIBUTIONmedicineHumansBovine serum albuminInternalization/dk/atira/pure/core/keywords/heart_SRImedia_commonchemistry.chemical_classificationKidneyPROTEIN-CORONAbiologyChemistryBLOOD-BRAIN-BARRIEREndothelial CellsBiological Transportrespiratory system021001 nanoscience & nanotechnologyCell biologyEndothelial stem cellSURFACE-CHARGEmedicine.anatomical_structureSIZENanomedicineTransferrinProtein coronabiology.proteinINTERNALIZATIONNanoparticlesProtein CoronaHeterogeneityMEMBRANE0210 nano-technologyEndothelial cell targetingInternational journal of pharmaceutics
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Genetic relationships between sympatric and allopatric Coregonus ciscoes in North and Central Europe

2021

Abstract Background Sympatric speciation along ecological gradients has been studied repeatedly, in particular in freshwater fishes. Rapid post-glacial ecological divergence has resulted in numerous endemic species or ecologically distinct populations in lakes of the temperate zones. Here, we focus on the Baltic cisco (Coregonus albula) complex, to study the genetic similarity among two pairs of sympatric autumn- and spring-spawning populations from post-glacial German Lakes Stechlin and Breiter Luzin. For comparison, we included a similar pair of sympatric populations from the Swedish Lake Fegen. We wanted to explore potential genetic similarities between the three sympatric cisco populati…

Biologisk systematikEvolutionmuikkuPopulationAllopatric speciationBaltic cisco complexBiological SystematicsBiologyEvolutionary ecologymikrosatelliititgenotyyppiPost-glacial divergencemicrosatellitesEvolutionsbiologispecies lossGenetic driftpost-glacial divergencepopulaatiotQH359-425Coregonus albulaAnimalsHumansCoregonusEndemismeducationMicrosatellitesQH540-549.5Coregonus albulaeducation.field_of_studyEvolutionary BiologyEcologyEcologyResearchlohikalatGeneral Medicinebiology.organism_classificationLakesSympatryGenetics PopulationSympatric speciationGenetic structureFish and Aquacultural SciencelajiutuminenSpecies lossSalmonidaeMicrosatellite Repeats
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Quantitative comparison of motion history image variants for video-based depression assessment

2017

Abstract Depression is the most prevalent mood disorder and a leading cause of disability worldwide. Automated video-based analyses may afford objective measures to support clinical judgments. In the present paper, categorical depression assessment is addressed by proposing a novel variant of the Motion History Image (MHI) which considers Gabor-inhibited filtered data instead of the original image. Classification results obtained with this method on the AVEC’14 dataset are compared to those derived using (a) an earlier MHI variant, the Landmark Motion History Image (LMHI), and (b) the original MHI. The different motion representations were tested in several combinations of appearance-based …

BiometricsComputer scienceSpeech recognitionlcsh:TK7800-836002 engineering and technologyConvolutional neural networkMotion (physics)[SPI]Engineering Sciences [physics]Image processingMachine learning0502 economics and business[ SPI ] Engineering Sciences [physics]0202 electrical engineering electronic engineering information engineeringElectrical and Electronic EngineeringCategorical variableComputingMilieux_MISCELLANEOUSLandmarkbusiness.industrylcsh:Electronics05 social sciencesAffective computingFacial image analysisPattern recognitionMotion history imageMoodSignal ProcessingPattern recognition (psychology)Depression assessment020201 artificial intelligence & image processingArtificial intelligenceF1 scorebusiness050203 business & managementInformation SystemsEURASIP Journal on Image and Video Processing
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HELMINTH ASSEMBLAGES OF WHITEFISH (COREGONUS LAVARETUS) IN INTERCONNECTED LAKES: SIMILARITY AS A FUNCTION OF SPECIES SPECIFIC PARASITES AND GEOGRAPHI…

2004

This article examined the composition of parasite assemblages of whitefish (Coregonus lavaretus) in 8 interconnected lakes in northeastern Finland and evaluated the role of coregonid specific parasites and the geographical distance between populations in determining the similarity of the assemblages. Parasite assemblages were compared using the Jaccard qualitative similarity index and a quantitative similarity index and by incorporating the allogenic-autogenic species concept and the effects of 2 corresponding measures of geographical distance between the lakes. The majority of the parasite species found (10 of 14) were specific to salmonids. Similarity of assemblages of autogenic parasites…

Biotopefood.dishEcologyZoologyFresh WaterBiologybiology.organism_classificationGeneralist and specialist speciesFish DiseasesfoodSpecies SpecificityCoregonus lavaretusGeographical distanceHelminthsFreshwater fishAnimalsRegression AnalysisParasite hostingDominance (ecology)ParasitologyHelminthiasis AnimalFinlandSalmonidaeEcology Evolution Behavior and SystematicsTrophic levelJournal of Parasitology
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Duration of untreated psychosis in first-episode psychosis is not associated with common genetic variants for major psychiatric conditions: results f…

2021

The EU-GEI Project is funded by the European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010–241909 (Project EU-GEI).

Bipolar DisorderTime FactorsIntelligenceGenome-wide association studyDETERMINANTSpsychosi0302 clinical medicineInterquartile rangeSettore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat.IMPUTATIONpolygenic scorepsychosis0303 health sciencesConfoundingEuropePsychiatry and Mental healthgenome-wide association studieSchizophreniaMajor depressive disorderlipids (amino acids peptides and proteins)Case-Control Studieduration of untreated psychosisBrazilHumanAdultPsychosismedicine.medical_specialtycongenital hereditary and neonatal diseases and abnormalitiesTime FactorAcademicSubjects/MED00810DISORDERS1ST EPISODEILLNESSPsychotic Disorderduration of untreated psychosi03 medical and health sciencesInternal medicinemedicineHumansBipolar disorderGENOME-WIDE ASSOCIATIONSettore MED/25 - PsichiatriaMETAANALYSIS030304 developmental biologyDepressive Disorder Majorbusiness.industryCOMPONENTSTREATMENT DELAYmedicine.diseaseTRANSTORNO BIPOLARschizophreniapolygenic scoresPsychotic DisordersCase-Control Studiesdupgenome-wide association studiesbusiness030217 neurology & neurosurgeryRegular ArticlesGenome-Wide Association Study
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Similar effectiveness of dapagliflozin and GLP-1 receptor agonists concerning combined endpoints in routine clinical practice: A multicentre retrospe…

2019

Abstract Aims According to cardiovascular outcome trials, some sodium‐glucose contransporter‐2 inhibitors (SGLT2i) and glucagon‐like peptide‐1 receptor agonists (GLP‐1RA) are recommended for secondary cardiovascular prevention in type 2 diabetes (T2D). In this real‐world study, we compared the simultaneous reductions in HbA1c, body weight and systolic blood pressure after initiation of dapagliflozin or GLP‐1RA as second or a more advanced line of therapy. Materials and methods DARWIN‐T2D was a retrospective multi‐centre study conducted at diabetes specialist clinics in Italy that compared T2D patients who initiated dapagliflozin or GLP‐1RA (exenatide once weekly or liraglutide). Data were c…

Blood GlucoseMaleGlycated Hemoglobin AEndocrinology Diabetes and MetabolismBlood PressureType 2 diabetes030204 cardiovascular system & hematologySettore MED/13 - Endocrinologiachemistry.chemical_compound0302 clinical medicineEndocrinologyGlucosidesClinical endpointMedicineDapagliflozinGLP-1 analogueMiddle AgedTreatment Outcomeglycaemic controlantidiabetic drug; dapagliflozin; GLP-1 analogue; glycaemic control; observational studyCombinationOriginal ArticleDrug Therapy CombinationFemaleType 2medicine.drugAdultmedicine.medical_specialty030209 endocrinology & metabolismGlucagon-Like Peptide-1 Receptor03 medical and health sciencesDrug TherapyGLP-1 analogue; antidiabetic drug; dapagliflozin; glycaemic control; observational studyGLP‐1 analogueInternal medicineDiabetes mellitusInternal MedicineDiabetes MellitusHumansHypoglycemic AgentsBenzhydryl CompoundsAgedRetrospective StudiesGlycated Hemoglobinantidiabetic drugantidiabetic drug; dapagliflozin; GLP-1 analogue; glycaemic control; observational study; Adult; Aged; Benzhydryl Compounds; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus Type 2; Diabetic Angiopathies; Drug Therapy Combination; Exenatide; Female; Glucagon-Like Peptide-1 Receptor; Glucosides; Glycated Hemoglobin A; Humans; Hypoglycemic Agents; Liraglutide; Male; Middle Aged; Retrospective Studies; Treatment Outcomebusiness.industryLiraglutideBody WeightRetrospective cohort studyOriginal ArticlesdapagliflozinLiraglutidemedicine.diseaseBlood pressureDiabetes Mellitus Type 2chemistryPropensity score matchingExenatideobservational studybusinessAntidiabetic drug dapagliflozin GLP-1 analogue glycaemic control observational studyDiabetic Angiopathies
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Impact of a Mediterranean Dietary Pattern and Its Components on Cardiovascular Risk Factors, Glucose Control, and Body Weight in People with Type 2 D…

2018

This study evaluates the relation of a Mediterranean dietary pattern and its individual components with the cardiovascular risk factors profile, plasma glucose and body mass index (BMI) in people with type 2 diabetes. We studied 2568 participants at 57 diabetes clinics. Diet was assessed with the EPIC (European Prospective Investigation into Cancer and Nutrition) questionnaire, adherence to the Mediterranean diet was evaluated with the relative Mediterranean diet score (rMED). A high compared to a low score was associated with a better quality of diet and a greater adherence to the nutritional recommendations for diabetes. However, even in the group achieving a high score, only a small prop…

Blood GlucoseMaleMediterranean diet; cardiovascular risk; diabetes; glucose control; plasma lipids; relative Mediterranean diet score; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus Type 2; Female; Glycated Hemoglobin A; Humans; Lipids; Male; Middle Aged; Nutritive Value; Patient Compliance; Protective Factors; Recommended Dietary Allowances; Risk Factors; Body Mass Index; Diet Healthy; Diet Mediterranean; Feeding BehaviorGlycated Hemoglobin AMediterranean dietRecommended Dietary AllowanceCross-sectional studyHealthy DietSaturated fatBlood PressureType 2 diabetes030204 cardiovascular system & hematologyMediterraneanDiet MediterraneanDiabeteRecommended Dietary AllowancesSettore MED/13 - EndocrinologiaBody Mass Indexchemistry.chemical_compound0302 clinical medicineRisk FactorsCardiovascular Disease030212 general & internal medicineNutrition and DieteticsdiabetesLipidMiddle AgedLipidsEuropean Prospective Investigation into Cancer and NutritionCardiovascular DiseasesFemaleDiet Healthylcsh:Nutrition. Foods and food supplyNutritive ValueType 2Humancardiovascular riskCardiovascular risk; Diabetes; Glucose control; Mediterranean diet; Plasma lipids; Relative mediterranean diet score; Aged; Biomarkers; Blood Glucose; Blood Pressure; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus Type 2; Female; Glycated Hemoglobin A; Humans; Lipids; Male; Middle Aged; Nutritive Value; Patient Compliance; Protective Factors; Recommended Dietary Allowances; Risk Factors; Body Mass Index; Diet Mediterranean; Feeding Behavior; Healthy Diet; Food Science; Nutrition and DieteticsPlasma lipidlcsh:TX341-641Article03 medical and health sciencesEnvironmental healthDiabetes mellitusMediterranean dietplasma lipidsmedicineDiabetes MellitusHumansProtective FactorAgedCross-Sectional StudieGlycated Hemoglobinglucose controlHealthybusiness.industryRisk FactorBiomarkerFeeding Behaviorrelative Mediterranean diet scoreProtective Factorsmedicine.diseaseDietCross-Sectional StudieschemistryDiabetes Mellitus Type 2Patient ComplianceGlycated hemoglobinbusinessBody mass indexBiomarkersFood Science
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Effects of a Mediterranean Eating Plan on the Need for Glucose-Lowering Medications in Participants With Type 2 Diabetes: A Subgroup Analysis of the …

2019

OBJECTIVE: To examine the effects of two Mediterranean eating plans (Med-EatPlans) versus a low-fat eating plan on the need for glucose-lowering medications. RESEARCH DESIGN AND METHODS: From the Prevención con Dieta Mediterránea (PREDIMED) trial, we selected 3,230 participants with type 2 diabetes at baseline. These participants were randomly assigned to one of three eating plans: Med-EatPlan supplemented with extra-virgin olive oil (EVOO), Med-EatPlan supplemented with mixed nuts, or a low-fat eating plan (control). In a subgroup (15%), the allocation was done in small clusters instead of using individual randomization, and the clustering effect was taken into account in the statistical a…

Blood GlucoseMaleResearch designmedicine.medical_specialtyRandomizationEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismSubgroup analysisType 2 diabetesDiet Mediterraneanlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawInternal medicineDiabetes mellitusInternal MedicinemedicineHumansHypoglycemic Agents030212 general & internal medicinePropensity ScoreDiet Fat-RestrictedOlive OilDieta -- Mediterrània Regió de laAgedProportional Hazards ModelsAdvanced and Specialized NursingDiabetisbusiness.industryHazard ratioClinical Care/Education/Nutrition/Psychosocial ResearchMiddle Agedmedicine.diseaseTreatment OutcomeDiabetes Mellitus Type 2Multivariate AnalysisPropensity score matchingFemale0405business
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