Search results for "Cores"

Genetic endowments, parental resources and adult health: Evidence from the Young Finns Study

2017

This paper uses longitudinal survey data linked to administrative registers to examine socioeconomic gradients in health, particularly whether the effects of genetic endowments interact with the socioeconomic resources of the parental household. We find that genetic risk scores contribute to adult health measured by biomarkers. This result is consistent with the findings from genome-wide association studies. Socioeconomic gradients in health differ based on biomarker and resource measures. Family education is negatively related to obesity and the waist-hip ratio, and family income is negatively related to low-density lipoprotein cholesterol and triglyceride levels. Parental resources do not…

Cumulative Prognostic Score Predicting Mortality in Patients Older Than 80 Years Admitted to the ICU

2019

OBJECTIVES To develop a scoring system model that predicts mortality within 30 days of admission of patients older than 80 years admitted to intensive care units (ICUs). DESIGN Prospective cohort study. SETTING A total of 306 ICUs from 24 European countries. PARTICIPANTS Older adults admitted to European ICUs (N = 3730; median age = 84 years [interquartile range = 81‐87 y]; 51.8% male). MEASUREMENTS Overall, 24 variables available during ICU admission were included as potential predictive variables. Multivariable logistic regression was used to identify independent predictors of 30‐day mortality. Model sensitivity, specificity, and accuracy were evaluated with receiver operating characteris…

Health-related quality of life is a prognostic factor for survival in older patients after colorectal cancer diagnosis: A population-based study

2015

International audience; Background: Studies carried out in the context of clinical trials have shown a relationship between survival and health-related quality of life in colorectal cancer patients.Aims: We assessed the prognostic value of health-related quality of life at diagnosis and of its longitudinal evolution on survival in older colorectal cancer patients. Methods: All patients aged >= 65 years, diagnosed with new colorectal cancer between 2003 and 2005 and registered in the Digestive Cancer Registry of Burgundy were eligible. Patients were asked to complete the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at inclusion, three, six …

Early-life weight gain, prematurity, and asthma development.

2014

Early childhood asthma is a clinical syndrome, the development and clinical manifestations of which result from a complex interplay among airway anatomy, physiology, and inflammation. Although multiple phenotypes of early childhood wheezing and asthma have been described, the mechanisms that promote and differentiate these phenotypes remain poorly understood. Over the past decade, substantial understanding has emerged as to the early-life factors that influence childhood asthma development. One area of great interest has been the relationships between patterns of fetal and infant growth, subsequent wheezing, and asthma. Although several studies strongly suggest that intrauterine growth patt…

Prognostic accuracy of Quick SOFA in older adults hospitalised with community acquired urinary tract infection

2021

Introduction Quick [Sepsis-related] Sequential Organ Failure Assessment (qSOFA) is a prognostic score based on sepsis-3 definition, easy to carry out, whose application has been studied in older adults with sepsis from different sources and respiratory sepsis. However, to date no study has analysed its prognostic accuracy in older adults admitted to hospital with community urinary tract infection. Methods In a prospective study of 282 older adults admitted to hospital with community acquired urinary tract infection, the application of qSOFA to predict hospital mortality was analysed. The predictive capacity of qSOFA for in-hospital mortality was compared with Systemic Inflammatory Response …

Performance Study of Split Ferrite Cores Designed for EMI Suppression on Cables

2020

The ideal procedure to start designing an electronic device is to consider the electromagnetic compatibility (EMC) from the beginning. Even so, EMC problems can appear afterward, especially when the designed system is interconnected with external devices. Thereby, electromagnetic interferences (EMIs) could be transmitted to our device from power cables that interconnect it with an external power source or are connected to another system to establish wired communication. The application of an EMI suppressor such as a sleeve core that encircles the cables is a widely used technique to attenuate EM disturbances. This contribution is focused on the characterization of a variation of this cable …

La location de l'usage : une interprétation écoresponsable du service ? : cas des biens en partage

2013

Offers of sharing services are springing up in cities: Vélib’, Autolib’, carsharing.... Using up involves sharing the service with multiple users and agreeing to separate oneself from all materialism in favor of functionality. This is also an argument towards a more responsible consumption. Hiring or buying, what does the consumer think about it? The value lies in the benefits of use rather than in its possession. It is also a new meaningful experience accepted, tinkered, refused or reinterpreted by the consumers. According to the Grounded Theory principles, a data collection based on life stories, it provides us new information on the attractiveness of this offer of service; and according …

Vascular risk factors in Alzheimer’s disease and Mild Cognitive Impairment: population data from the Zabùt Aging Project

Background: Alzheimer's disease (AD) is the most common cause of dementia in older adults, accounting for about 60% of cases. However, autopsy studies suggested that mixed dementia, with vascular and neurodegenerative AD pathology, accounts for nearly 20% of dementia cases. Aims: Aim of the present study was to evaluate the relationship between isolated or clustered Vascular Risk Factors (VRFs)/diseases and Mild Cognitive Impairment (MCI) or AD. The study was conducted using a Sicilian population-based cohort dataset collected in low-educated, rural subjects, the Zabùt Aging Project (ZAP). The effect-modification by age, sex, education, genetic factor (APOE4 allele carrier), undernutrition,…

Rank scores tests of multivariate independence

2004

New rank scores test statistics are proposed for testing whether two random vectors are independent. The tests are asymptotically distribution-free for elliptically symmetric marginal distributions. Recently, Gieser and Randles (1997), Taskinen, Kankainen and Oja (2003) and Taskinen, Oja and Randles (2005) introduced and discussed different multivariate extensions of the quadrant test, Kendall's tau and Spearman's rho statistics. In this paper, standardized multivariate spatial signs and the (univariate) ranks of the Mahalanobis-type distances of the observations from the origin are combined to construct ranks cores tests of independence. The limiting distributions of the test statistics ar…

Indentation of rigidly supported sandwich beams with foam cores exhibiting non-linear compressive behaviour.

2011

A generalized analytical approach to investigate the indentation of sandwich beams under concentrated loads is presented, based on the Winkler foundation theory. A segment-wise model is implemented to the case of fully backed sandwich beams with polymeric foam cores exhibiting generic non-linear compressive behaviours. Closed-form analytical solutions of the indentation curve are obtained for simplified foam compression behaviours: elastic-perfectly-plastic, bilinear and bilinear-perfectly-plastic. Analytical predictions are compared with experimental data from sandwiches employing foam cores with peculiar non-linear behaviours. The proposed models are found to give a better match of the e…