Search results for "Correlation"

showing 10 items of 2282 documents

Assisted baseline subtraction in complex chromatograms using the BEADS algorithm.

2017

The data processing step of complex signals in high-performance liquid chromatography may constitute a bottleneck to obtain significant information from chromatograms. Data pre-processing should be preferably done with little (or no) user supervision, for a maximal benefit and highest speed. In this work, a tool for the configuration of a state-of-the-art baseline subtraction algorithm, called BEADS (Baseline Estimation And Denoising using Sparsity) is developed and verified. A quality criterion based on the measurement of the autocorrelation level was designed to select the most suitable working parameters to obtain the best baseline. The use of a log transformation of the signal attenuate…

AcetonitrilesNoise reduction02 engineering and technology01 natural sciencesBiochemistrySignalAnalytical ChemistryPolyethylene GlycolsBaseline (configuration management)Chromatography High Pressure LiquidData processingElectronic Data ProcessingChromatographyElutionChemistry010401 analytical chemistryOrganic ChemistryAutocorrelationProcess (computing)General Medicine021001 nanoscience & nanotechnologySample (graphics)0104 chemical sciences0210 nano-technologyAlgorithmAlgorithmsJournal of chromatography. A
researchProduct

The Choice of Performance Measure Does Influence the Evaluation of Hedge Funds

2010

It is widely accepted that, when return distributions are non-normal, the use of the Sharpe ratio can lead to misleading conclusions. It is well documented that deviations of hedge fund return distributions from normality are statistically significant. The literature on performance evaluation that takes into account the non-normality of return distributions is a vast one. However, there is another stream of research that advocates that the choice of performance measure does not influence the evaluation of hedge funds. For example, Eling and Schuhmacher (2007) and Eling (2008) performed empirical studies and, judging by the values of rank correlations, concluded that the choice of performanc…

Actuarial sciencebusiness.industrymedia_common.quotation_subjectSharpe ratioMeasure (mathematics)Hedge fundInformation ratioEmpirical researchSkewnessEconomicsEconometricsbusinessNormalitymedia_commonRank correlationSSRN Electronic Journal
researchProduct

Is lithium implicated in tobacco addiction?

2016

IntroductionTobacco is a source of mineral elements that can affect human health in various ways, such as lithium, which is used as a psychiatric medication. Lithium salts are used as mood-stabilizing drugs and indicated in the treatment of manic-depressive psychosis.ObjectiveStudying the lithium content in tobacco over the smokers’plasma content and evaluate the potential role of lithium in tobacco addiction.MethodsA total of 18 different tobacco products (cigarettes, smokeless and water pipe tobacco) and 125 plasma samples (45 from smokers, 10 from ex-smokers and 70 from non-smokers) were collected to determinate the lithium content. Tobacco samples were digested with nitric acid and lith…

Addictionmedia_common.quotation_subjectSignificant differencechemistry.chemical_elementSignificant negative correlationLithium levelPsychiatry and Mental healthchemistrySmokeless tobaccoWater pipeLithium Tokamak ExperimentLithiumFood sciencemedia_commonEuropean Psychiatry
researchProduct

Transition from Youth categories to Elite cycling: relationships between early career performance and UCI World Tour success

2021

BACKGROUND The present study aimed to describe the possible roles of cyclists' early career performance, on the transition process to elite cycling categories. METHODS Data from national and international databases, and results achieved during the UCI World Championships, were retrospectively analysed considering the Italian national Youth-U16, Junior-U18, and U23 categories, and international Junior-U18 and UCI World-Tour categories. RESULTS The 15% of Youth-U16, the 38.8% of Junior-U18 and the 60% of U23 athletes who ranked top-10 between 2007 and 2013, scored points in UCI World Tour competitions between 2012 and 2018. The 1.6% of Youth-U16, the 8.3% of Junior-U18 and 25% of U23 athletes…

AdolescentbiologyAthletesPhysical Therapy Sports Therapy and RehabilitationAthletic PerformanceAchievementbiology.organism_classificationBicyclingAthletesEliteWorld championshipHumansOrthopedics and Sports MedicineEarly careerLow correlationCyclingPsychologyRetrospective StudiesDemographyThe Journal of Sports Medicine and Physical Fitness
researchProduct

Homozygous familial hypercholesterolemia in Italy: Clinical and molecular features

2020

Abstract Background and aims Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by extremely elevated plasma levels of low density lipoprotein cholesterol (LDL-C) and high risk of premature atherosclerotic cardiovascular disease (ASCVD). HoFH is caused by pathogenic variants in several genes, such as LDLR, APOB and PCSK9, responsible for autosomal dominant hypercholesterolemia (ADH), and LDLRAP1 responsible for autosomal recessive hypercholesterolemia (ARH). Aim of this study was the review of the clinical and molecular features of patients with HoFH identified in Italy from 1989 to 2019. Methods Data were collected from lipid clinics and laboratories, …

Adult0301 basic medicinemedicine.medical_specialtyCandidate geneCandidate geneGenotype-phenotype correlationApolipoprotein BCandidate genes; Genotype-phenotype correlations; Homozygous familial hypercholesterolemia; Pathogenic variantsHomozygous familial hypercholesterolemiaGenotype-phenotype correlationsFamilial hypercholesterolemia030204 cardiovascular system & hematologyCompound heterozygosityCandidate genesHyperlipoproteinemia Type II03 medical and health sciences0302 clinical medicineInternal medicinemedicineHumansbiologybusiness.industryPCSK9HomozygoteGenetic disorderPathogenic variantsCandidate genes; Genotype-phenotype correlations; Homozygous familial hypercholesterolemia; Pathogenic variants;medicine.diseasePhenotype030104 developmental biologyEndocrinologyItalyReceptors LDLAutosomal Recessive HypercholesterolemiaMutationLDL receptorbiology.proteinlipids (amino acids peptides and proteins)Proprotein Convertase 9Cardiology and Cardiovascular Medicinebusiness
researchProduct

Sister-chromatid exchange in cultured lymphocytes of ewes and their newborn lambs

1984

The incidence of sister-chromatid exchange (SCE) in cultured lymphocytes of ewes and their newborn lambs was determined using the BrdU-Giemsa technique. In all ewe-lamb pairs, the SCE rate in the lambs was less than that of the ewes. The mean SCE frequencies per chromosome of the ewes after lambing and of the newborn lambs were 0.1909 and 0.1581, respectively. The statistical analysis shows that a significant difference exists between SCE in the adult female sheep and their lambs. At the same time, a negative correlation was observed between SCE rate and cell proliferation. The results of this study are compared with those of previous reports on age-dependency of SCE.

AdultAgingAdolescentanimal diseasesSister chromatid exchangeBiologyAndrologyPregnancyparasitic diseasesAnimalsHumansStatistical analysisCrossing Over GeneticLymphocytesChildCells CulturedAgedGeneticsSheepAdult femaleIncidence (epidemiology)Domestic sheep reproductionSignificant differenceInfant NewbornInfantChromosomeGeneral MedicineMiddle Agedrespiratory systemAnimals NewbornChild PreschoolFemaleNegative correlationSister Chromatid ExchangeCell DivisionMutation Research Letters
researchProduct

Correlation between different degree and duration of metabolic control and thyroid hormone levels in type 1 and type 2 diabetics.

1983

Thyroxine (T4), triiodothyronine (T3), reverse T3 (rT3) and HbA1c were assayed in 21 insulin-dependent (type 1) diabetics and in 45 non-insulin-dependent (type 2) diabetics with normal thyroid function and different levels of control, and were compared to values found in apparently healthy controls. rT3 and rT3/T3 ratio were significantly increased both in type 1 and type 2 diabetics. T3 and T4 were significantly lower in type 2 diabetics than in the controls. Significant positive correlations of HbA1c to rT3 (r = 0.63) and to rT3/T3 ratio (r = 0.53) were found in type 1, and in type 2 diabetics (HbA1c, rT3-r = 0.50), (HbA1c, rT3/T3-r = 0.37). There was no correlation between glycemia (BG),…

AdultBlood GlucoseMaleendocrine systemmedicine.medical_specialtyThyroid Hormonesendocrine system diseasesAdolescentTriiodothyronine ReverseEndocrinology Diabetes and MetabolismCorrelationEndocrinologyDiabetes mellitusInternal medicineInternal MedicinemedicineHumansAgedGlycated HemoglobinTriiodothyroninebusiness.industryThyroidType 2 Diabetes MellitusGeneral MedicineMiddle Agedmedicine.diseaseThyroxinemedicine.anatomical_structureEndocrinologyDiabetes Mellitus Type 1Diabetes Mellitus Type 2Thyroid hormonesMetabolic control analysisTriiodothyronineFemalebusinesshormones hormone substitutes and hormone antagonistsHormoneActa diabetologica latina
researchProduct

Determination of salivary glucose in healthy adults

2009

Podeu consultar la versió en castellà a: http://hdl.handle.net/2445/54584

AdultBlood GlucoseMalemedicine.medical_specialtySalivaDiagnòsticInternal medicineDiagnosismedicineHumansWhole salivaSalivaGeneral Dentistrybusiness.industrySignificant difference:CIENCIAS MÉDICAS [UNESCO]Spearman Correlation TestEndocrinologySalivary glucoseGlucoseOtorhinolaryngologyHealthy individualsGlucosaUNESCO::CIENCIAS MÉDICASSurgeryFemalebusiness
researchProduct

Correlation of an estrogen receptor-related phosphoprotein with histopathological features in breast cancer.

1989

A series of 65 cases of different histological types of breast carcinoma was investigated for the immunohistochemical location of the estrogen receptor-related, 29 kD phosphoprotein using the ER-D5 monoclonal antibody.The ER-D5 response is heterogeneous in relation to some therapeutic limitations and is correlated with histopathological features of the tumors and survival. The main parameters for evaluation of breast cancers are reviewed, both those that are statistically correlated and those that are not apparently always correlated but are known to have considerable biological meaning, such as the ER-status of tumors.

AdultCancer ResearchPathologymedicine.medical_specialtymedicine.drug_classClinical BiochemistryEstrogen receptorBreast NeoplasmsAdenocarcinomaMonoclonal antibodyPathology and Forensic MedicineCorrelationBreast cancermedicineBiomarkers TumorHumansNeoplasm InvasivenessAgedAged 80 and overbusiness.industryMiddle Agedmedicine.diseasePhosphoproteinsAdenocarcinoma MucinousCarcinoma PapillaryCarcinoma Intraductal NoninfiltratingOncologyReceptors EstrogenEstrogenPhosphoproteinImmunohistochemistrybusinessBreast carcinomaThe International journal of biological markers
researchProduct

RCBF-quantification with 99mTc-HMPAO-SPECT: theory and first results.

1989

The activity concentrations of 99mTc-HMPAO in brain after intravenous injection were evaluated in 25 patients using SPECT. With additional first pass studies of heart and brain with the short lived isotope 195mAu, the cardiac output and the mean cerebral transit times of the patients were measured a short time before the HMPAO injection. The time dependence of 99mTc-HMPAO activity in the brain was registered during the first 5 min after injection over both hemispheres. Using a simplified three compartment model it was possible to calculate the mean retention fraction of HMPAO in brain from the time activity curves. It could be shown that the regional cerebral blood flow in ml/min per 100 g …

AdultCardiac outputCorrelation coefficientAdolescentHemodynamicsGrey matterTechnetium Tc 99m ExametazimeOximesmedicineOrganometallic CompoundsHumansRadiology Nuclear Medicine and imagingChild99mtc hmpao spectAgedmedicine.diagnostic_testbusiness.industryBrainTechnetiumGeneral MedicineMiddle Agedmedicine.anatomical_structureCerebral blood flowPositron emission tomographyCerebrovascular CirculationbusinessNuclear medicineTechnetium-99mTomography Emission-ComputedEuropean journal of nuclear medicine
researchProduct