6533b86efe1ef96bd12cb5ea
RESEARCH PRODUCT
Correlation of an estrogen receptor-related phosphoprotein with histopathological features in breast cancer.
Salvato MAda Maria FlorenaRosa Maria TomasinoDaniele ER. NuaraVincenza Morellosubject
AdultCancer ResearchPathologymedicine.medical_specialtymedicine.drug_classClinical BiochemistryEstrogen receptorBreast NeoplasmsAdenocarcinomaMonoclonal antibodyPathology and Forensic MedicineCorrelationBreast cancermedicineBiomarkers TumorHumansNeoplasm InvasivenessAgedAged 80 and overbusiness.industryMiddle Agedmedicine.diseasePhosphoproteinsAdenocarcinoma MucinousCarcinoma PapillaryCarcinoma Intraductal NoninfiltratingOncologyReceptors EstrogenEstrogenPhosphoproteinImmunohistochemistrybusinessBreast carcinomadescription
A series of 65 cases of different histological types of breast carcinoma was investigated for the immunohistochemical location of the estrogen receptor-related, 29 kD phosphoprotein using the ER-D5 monoclonal antibody.The ER-D5 response is heterogeneous in relation to some therapeutic limitations and is correlated with histopathological features of the tumors and survival. The main parameters for evaluation of breast cancers are reviewed, both those that are statistically correlated and those that are not apparently always correlated but are known to have considerable biological meaning, such as the ER-status of tumors.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1989-04-01 | The International journal of biological markers |