Search results for "Coste"
showing 10 items of 368 documents
Predictors for Therapy Response to Intrathecal Corticosteroid Therapy in Multiple Sclerosis
2019
\(\bf Objective:\) The autoimmune disease Multiple Sclerosis (MS) represents a heterogeneous disease pattern with an individual course that may lead to permanent disability. In addition to immuno-modulating therapies patients benefit from symptomatic approaches like intrathecal corticosteroid therapy (ICT), which is frequently applied in a growing number of centers in Germany. ICT reduces spasticity, which elongates patient's walking distance and speed, thus improves quality of life. \(\bf Methods:\) In our study we set out to investigate cerebrospinal fluid (CSF) parameters and clinical predictors for response to ICT. Therefore, we analyzed 811 CSF samples collected from 354 patients over …
La Pequeña Edad de Hielo en el Golfo de València. Procesos en deltas y sistemas de restinga-albufera. La desestabilización reciente
2023
En este proyecto de Tesis, se ha pretendido caracterizar formas, procesos y dinámica de sistemas de delta-laguna-barrera a escala de tiempo histórica relacionados con el episodio climático histórico de la Pequeña Edad de Hielo (PEH, siglos XIV-XIX) en el Golfo de València. Finalmente, también se aborda el análisis de la desestabilización de estos sistemas ante la acción antrópica y el Calentamiento Global. Los deltas, las barreras (o restingas) y los humedales (o albuferas) mediterráneos constituyen ambientes altamente sensibles a los cambios tanto de origen natural como antrópico. La franja costera del Golfo de València, formada por un conjunto prácticamente ininterrumpido de sistemas de d…
Individual vulnerability to stress is associated with increased demand for intravenous heroin self-administration in rats
2019
AbstractOpioid use is a widespread epidemic, and traumatic stress exposure is a critical risk factor in opioid use and relapse. There is a significant gap in our understanding of how stress contributes to heroin use, and there are limited studies investigating individual differences underlying stress reactivity and subsequent stress-induced heroin self-administration. We hypothesized that greater individual vulnerability to stress would predict higher demand for heroin self-administration in a within-subjects rodent model of stress and heroin use comorbidity. Male rats were exposed to inescapable intermittent swim stress and individual biological (corticosterone) or behavioral (open field, …
Evaluación del comportamiento energético de las estaciones depuradoras de aguas residuales: Una aproximación económica
2019
Las Estaciones Depuradoras de Aguas Residuales (EDARs) son una pieza básica del conjunto de infraestructuras urbanas, ya que son indispensables para garantizar la salud pública y del medio ambiente. Actualmente, en España existen aproximadamente 3.000 EDARs que tratan 4.700 hm3 de aguas residuales, de los cuales la mayor parte, un 55,8% y un 33,5% son vertidos a cauces fluviales y al mar, respectivamente, mientras que un 10,4% es reutilizado en la agricultura y el riego de jardines, y el 0,3% restante es infiltrado al suelo para la regeneración de acuíferos y otros fines. Según el destino del agua residual, la normativa en materia de aguas residuales urbanas y reutilización requiere el cump…
Zeitlicher Ablauf der ACTH-induzierten Stimulierung der Corticosteroidbiosynthese
1969
The time course of ACTH action was studied during incubation of quartered rat adrenals by estimation of corticosterone production and secretion rates. The results suggest a two step action of ACTH during the acute stimulation of corticosteroid biosynthesis: A modest initial stimulation was observed within the first 30 min of exposure to ACTH which was overlapped by a marked secondary stimulation between 30 and 60 min.
Context dependent variation in corticosterone and phenotypic divergence of Rana arvalis populations along an acidification gradient
2022
Background Physiological processes, as immediate responses to the environment, are important mechanisms of phenotypic plasticity and can influence evolution at ecological time scales. In stressful environments, physiological stress responses of individuals are initiated and integrated via the release of hormones, such as corticosterone (CORT). In vertebrates, CORT influences energy metabolism and resource allocation to multiple fitness traits (e.g. growth and morphology) and can be an important mediator of rapid adaptation to environmental stress, such as acidification. The moor frog, Rana arvalis, shows adaptive divergence in larval life-histories and predator defense traits along an acidi…
Clasificación de los costes de calidad en la gestión de la calidad total
2004
Resumen: En este trabajo queremos resaltar la importancia de los costes de calidad, entrando en el fondo de su definición y no centrarnos sólo en las clasificaciones generalmente aceptadas, si no, que a partir de estas plantear una clasificación más profunda y extensa, en donde se puedan clasificar los costes de calidad, además de por los conceptos tradicionales, por conceptos como el origen de los mismos costes.
Coste y financiacion de la universidad espanola
1986
International audience; Education, as any other activity, is hard to produce. Not only is it difficult to produce for the community in charge of teaching services, but also for the fellows who receive the instruction, as they bear, besides the direct expenses of their education, the opportunity costs, mainly in form of an unwon salary. We will primordially refer to the first of the two mentioned aspects of the cost of higher education, without denying the importance of the private expenses in higher education-rather difficult to cipher as a result of the shortage of adequate statistics, on the other hand. In that way, the purpose of this work is, firstly, to describe the recent evolution of…
Estudio del sentido de enrollamiento en los foraminíferos bentónicos del Marjal de Torreblanca (Castellón)
2021
Se ha analizado el sentido de enrollamiento de siete especies de foraminíferos bentónicos procedentes del marjal de Torreblanca localizado al norte de la Comunidad Valenciana, Este de España. Si bien en ninguna especie se ha observado un marcado predominio en el sentido de enrollamiento, dos de ellas muestran una preferencia leve pero estadísticamente significativa: Ammonia beccarii tepida es predominantemente dextrógira y Metarotaliella simplex? preferentemente levógira. Trochammina inflata, Jadammina macrescens y Rubratella sp. no muestran preferencia alguna en el sentido de enrollamiento. En Torreblanca no se ha observado ninguna relación entre la tendencia de enrollamiento y los parámet…
Adverse reactions to the injection of face and neck aesthetic filling materials: a systematic review
2022
Adverse reactions, caused during the inflammation and healing process, or even later, can be induced by the injection of dermal filler and can present a variety of clinical and histological characteristics. In this study we aimed to review the adverse reactions associated with the injection of aesthetic filling materials in the face and neck. The review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist. Studies published that mentioned adverse reactions in patients with aesthetic filling materials in the face or neck were included. Risk of bias was assessed using the Joanna Briggs Institute appraisal tool. After a 2-step selection pro…