Search results for "Cripto"

Writer identification for historical handwritten documents using a single feature extraction method

2020

International audience; With the growth of artificial intelligence techniques the problem of writer identification from historical documents has gained increased interest. It consists on knowing the identity of writers of these documents. This paper introduces our baseline system for writer identification, tested on a large dataset of latin historical manuscripts used in the ICDAR 2019 competition. The proposed system yielded the best results using Scale Invariant Feature Transform (SIFT) as a single feature extraction method, without any preprocessing stage. The system was compared against four teams who participated in the competition with different feature extraction methods: SRS-LBP, SI…

Knowledge-based strategy to trigger grapevine immunity

2012

The Medicago truncatula hypermycorrhizal B9 mutant displays an altered response to phosphate and is more susceptible to Aphanomyces euteiches.

2014

SPE IPM; National audience; Inorganic phosphate (Pi) plays a key role in the development of arbuscular mycorrhizal (AM) symbiosis, which is favoured when Pi is limiting in the environment. We have characterized the Medicago truncatula hypermycorrhizal B9 mutant for its response to limiting (P/10) and replete (P2) Pi. On P2, mycorrhization was significantly higher in B9 plants than in wild-type (WT). The B9 mutant displayed hallmarks of Pi-limited plants, including higher levels of anthocyanins and lower concentrations of Pi in shoots than WT plants. Transcriptome analyses of roots of WT and B9 plants cultivated on P2 or on P/10 confirmed the Pi-limited profile of the mutant on P2 and highli…

Genetic determinisms, evolution and detection of non-target-site based resistance to herbicides inhibiting acetolactate-synthase in rye-grass (Lolium…

2016

The aim of this study is to unravel the genetic determinism of non-target-site resistance (NTSR) to herbicides inhibiting acetolactate-synthase (ALS) in the major weed rye-grass (Lolium sp.), and to estimate the feasibility of NTSR diagnosis based on genetic data. On the one hand, this work contributes to the understanding of the processes driving the evolution of NTSR to herbicides, and on the other hand it lays the foundations for the development of a diagnosis tool to identify NTSR to ALS inhibiting herbicides. - Using a quantitative transcriptome sequencing approach, we showed that NTSR evolve by recurrent selection of higher and higher constitutive expression levels of genes involved i…

Intraseasonal descriptors and rainfall extremes in austral summer over South Africa : Observations and Meso-scale modelling

2022

Rainfall extremes are of major and increasing importance in semi-arid countries and their variability has strong implications for water resource and climate impacts on the local societies and environment. Here, we examine intraseasonal descriptors (ISDs) and wet extremes in austral summer rainfall (November−February) over South Africa (SA). Using daily observations from 225 rain gauges and ERA5 reanalysis between 1979 and 2015, we propose a novel typology of wet extreme events based on their spatial fraction, thus differentiating large- and small-scale extremes. Long-term variability of both types of extreme rainfall events is then extensively discussed in the context of ISDs. Following the…

Single-cell RNA sequencing unveils the shared and the distinct cytotoxic hallmarks of human TCRVδ1 and TCRVδ2 γδ T lymphocytes

2019

γδ T lymphocytes represent ∼1% of human peripheral blood mononuclear cells and even more cells in most tissues of vertebrates. Although they have important anticancer functions, most current single-cell RNA sequencing (scRNA-seq) studies do not identify γδ T lymphocytes because their transcriptomes at the single-cell level are unknown. Here we show that high-resolution clustering of large scRNA-seq datasets and a combination of gene signatures allow the specific detection of human γδ T lymphocytes and identification of their T cell receptor (TCR)Vδ1 and TCRVδ2 subsets in large datasets from complex cell mixtures. In t -distributed stochastic neighbor embedding plots from blood and tumor sa…

The multiple facets of Cajal-Retzius neurons.

2021

ABSTRACTCajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs lies in the fact they are initially embedded into the immature neuronal network before being almost completely eliminated by cell death at the end of cortical development. CRs are best known for controlling the migration of glutamatergic neurons and the formation of cortical layers through the secretion of the glycoprotein reelin. However, they have been shown to play numerous additional key roles at many steps of cortical development, spanning from patterning and sizing functional areas to synaptogenesis. The use of genetic l…

Characterization and role of nitric oxide production in Arabidopsis thaliana defense responses induced by oligogalacturonides

2011

Nitric oxide (NO) regulates a wide range of plant processes from development toenvironmental adaptation. In this study, NO production and its effects were investigated in aplant-pathogen context. The production of NO following Arabidopsis treatment witholigogalacturonides (OGs), an endogenous elicitor of plant defense, was assessed using the NOsensitive probe 4, 5-diamino fluorescein diacetate. Pharmacological and genetic approaches wereused to analyze NO enzymatic sources and its role in the Arabidopsis thaliana /Botrytis cinereainteraction. We showed that NO production involves both a L-arginine- and a nitrate reductase(NR)-pathways. OGs-induced NO production was Ca2+-dependent and modula…

The antennal transcriptome of a moth

2010

International audience

Role of nitric oxide in tumor development. Role of HSF1 in development of zebrafish embryos in non heat-shocked conditions

2014

The use of animal models has led to the discovery of important mechanisms of biology development in general, and tumor development in particular, to establish and develop new treatments. The Zebrafish (Danio rerio) is increasingly used nowadays as part of this research because of its many advantages such as the transparency of the larvae, and the high homology with human. Several approaches have been developed in this fish, as the gene-knockdown in order to identify the role of a protein in the development, or the tumor transplantation of mammalian cells to study anti-tumor treatments response.It is in one of these two contexts that we studied the role of nitric oxide in tumor development i…