Search results for "Cru"

showing 10 items of 1385 documents

In vitro antifungal activity of allyl isothiocyanate (AITC) against Aspergillus parasiticus and Penicillium expansum and evaluation of the AITC estim…

2015

Abstract Isothiocyanates (ITCs) are natural compounds derived from cruciferous vegetables produced by enzymatic conversion of metabolites called glucosinolates. They are potentially useful antimicrobial compounds for food applications have been shown to be promising agents against cancer in human cell culture, animal models, and in epidemiological studies. In this study, the antifungal activity of the allyl isothiocyanate (AITC) was evaluated on two mycotoxigenic fungi as Aspergillus parasiticus and Penicillium expnsum , aflatoxins (AFs) and patulin (PAT) producers, employing an assay on solid medium. Also an approximation of the risk evaluation associated to the intake of food treated with…

AdultMaleAntifungal AgentsAdolescentFood spoilageToxicologyRisk AssessmentMicrobiologyPatulinYoung Adultchemistry.chemical_compoundDisk Diffusion Antimicrobial TestsIsothiocyanatesVegetablesHumansFood scienceChildAgedAged 80 and overbiologyCruciferous vegetablesPenicilliumGeneral MedicineMiddle Agedbiology.organism_classificationAllyl isothiocyanateBioactive compoundAspergillus parasiticusAspergilluschemistrySpainBrassicaceaePenicilliumFood PreservativesFemalePenicillium expansumFood ScienceFood and Chemical Toxicology
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A new approach to examine the relationships between sensory and gas chromatography-olfactometry data using generalized procrustes analysis applied to…

2003

Six French Chardonnay wines were submitted to both sensory and combined headspace/gas chromatography-olfactometry analyses. The detection frequencies allowed five hierarchical levels to be distinguished: P25, the odorant areas (OAs) having a detection frequencyor =25% (the complete olfactogram without the odor noise); P40,or =40%; P55,or =55%; P70,or =70%; and P85,or =85%. Moreover, the detection frequencies were analyzed to distinguish 21 discriminative OAs. Wines tested by sensory analysis and the headspace samples analyzed by gas chromatography-olfactometry (GC-O) were described by a heterogeneous vocabulary distributed into nine overall classes of descriptors. The new statistical treatm…

AdultMaleChromatography GasSensory systemWine01 natural sciencesSensory analysisCorrespondence analysis0404 agricultural biotechnologyDiscriminative modelOlfactometry[SDV.IDA]Life Sciences [q-bio]/Food engineeringHumansComputingMilieux_MISCELLANEOUSMathematicsChromatographybusiness.industry010401 analytical chemistryGeneralized Procrustes analysisPattern recognition04 agricultural and veterinary sciencesGeneral Chemistry[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food science0104 chemical sciencesOdorTasteOdorantsFemaleArtificial intelligenceGas chromatographyFranceVolatilizationGeneral Agricultural and Biological Sciencesbusiness
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Collagen ultrastructure in ruptured cruciate ligaments

1992

The ultrastructure of collagen fibrils was investigated in normal (n 39) and ruptured (n 23) human anterior cruciate ligaments. The normal ligament had a complex three-dimensional structure. Collagen fibrils predominantly had a unidirectional course with parallel arrangement and a mean diameter of 75 (20-185) nm. Four days after anterior cruciate ligament rupture, the mean fibril diameter was increased; it later decreased, probably due to synthesis of young, thin 30-40 nm fibrils. Interfibrillar dysplastic collagen fibrils were detected in the extracellular matrix of ruptured ligaments. They were more frequently found later than 3 days after rupture and were seen also at a distance of 2-3 c…

AdultMaleMicroscopy Electron Scanning TransmissionPathologymedicine.medical_specialtyTime FactorsAdolescentAnterior cruciate ligamentmacromolecular substancesFibrillaw.inventionExtracellular matrixlawmedicineHumansOrthopedics and Sports MedicineElectron microscopicRupturebusiness.industryAnterior Cruciate Ligament InjuriesAnatomyMiddle Agedmedicine.anatomical_structureRepair tissueEvaluation Studies as TopicMicroscopy Electron ScanningUltrastructureLigamentWounds and InjuriesFemaleSurgeryCollagenElectron microscopebusinessActa Orthopaedica Scandinavica
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Interrelationships between electromyographic, mechanical, muscle structure and reflex time measurements in man.

1981

Reaction time (TRT) with its premotor (PMT) and motor time (MT) components, patellar reflex time (TRfT) with its latency (LAT) and motor time (RfMT) were studied together with isometric force production and relaxation time variables in one leg isometric knee extension. These variables were intercorrelated together with muscle biopsy variables taken from m. vastus lateralis. From these computations MT proved to demonstrate significant correlations to rate of isometric force development (RFD) (P less than 0.001), maximum force (P0) (P less than 0.001) and per cent distribution of ST fibers (P less than 0.001). It is speculated that these relationships are determined by the pattern of the moto…

AdultMaleMuscle biopsyTime Factorsmedicine.diagnostic_testPhysiologyChemistryElectromyographyMuscle RelaxationMusclesPatellar reflexAnatomyElectromyographyIsometric exerciseMuscle relaxationIsometric ContractionMotor unit recruitmentReflexReflexmedicineReaction TimeHumansmedicine.symptomMuscle contractionMuscle ContractionActa physiologica Scandinavica
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Cellular ultrastructure of the ruptured anterior cruciate ligament. A transmission electron microscopic and immunohistochemical study in 55 cases.

1994

To evaluate the cellular ultrastructure following injury, we examined the anterior cruciate ligaments in 55 patients with complete tears in different phases after the injury and compared them to a control group of 39 cadaver knees. Samples were analyzed by electron microscopy, immunofluorescence, and ultramorphometry. After an invasion of inflammatory cells into the stumps of the ruptured ligaments, a marked proliferation of fibroblasts was found at the end of Phase 1 (2-3 days after the ligament injury), that was even more pronounced at the beginning of Phase II (4-17 days). These cells were initially highly metabolically active and secreted Type III collagen precursors. In Phase III (4-45…

AdultMalePathologymedicine.medical_specialtyAdolescentKnee JointAnterior cruciate ligamentBiopsyFluorescent Antibody TechniqueImmunofluorescenceBiopsymedicineCadaverHumansOrthopedics and Sports MedicineAnterior Cruciate LigamentFibroblastRuptureWound Healingmedicine.diagnostic_testbusiness.industryAnterior Cruciate Ligament InjuriesAnatomyFibroblastsMiddle AgedMicroscopy Electronmedicine.anatomical_structureUltrastructureTearsImmunohistochemistrySurgeryFemaleWound healingbusinessCell DivisionActa orthopaedica Scandinavica
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Enhancement of human cortico-motoneuronal excitability by the selective norepinephrine reuptake inhibitor reboxetine

2002

It has been proposed that norepinephrine plays a critical role in the modulation of cortical excitability, which in turn is thought to influence functional recovery from brain lesions. The purpose of the present experiments was to determine if it is possible to modulate cortical excitability with the selective norepinephrine reuptake inhibitor reboxetine in intact humans. Recruitment curve and intracortical facilitation, assessed by transcranial magnetic stimulation, were increased after oral intake of 8 and 4 mg reboxetine, in the absence of changes in motor threshold, intracortical inhibition, M-response, F-wave or H-reflex. These results demonstrate that reboxetine enhances cortical exci…

AdultMaleRecruitment NeurophysiologicalMorpholinesmedicine.medical_treatmentCentral nervous systemNorepinephrine (medication)MagneticsReboxetinemedicineHumansNeurorehabilitationAdrenergic Uptake InhibitorsElectromyographyGeneral NeuroscienceReboxetineMotor CortexNeural InhibitionEvoked Potentials MotorTranscranial magnetic stimulationmedicine.anatomical_structureCatecholamineReuptake inhibitorPsychologyNeuroscienceMotor cortexmedicine.drugNeuroscience Letters
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Motor recruitment during action observation: Effect of interindividual differences in action strategy

2020

Abstract Visual processing of other’s actions is supported by sensorimotor brain activations. Access to sensorimotor representations may, in principle, provide the top-down signal required to bias search and selection of critical visual features. For this to happen, it is necessary that a stable one-to-one mapping exists between observed kinematics and underlying motor commands. However, due to the inherent redundancy of the human musculoskeletal system, this is hardly the case for multijoint actions where everyone has his own moving style (individual motor signature—IMS). Here, we investigated the influence of subject’s IMS on subjects’ motor excitability during the observation of an actor…

AdultMaleRecruitment NeurophysiologicalMultijoint actionsDissociation (neuropsychology)Cognitive Neurosciencemedicine.medical_treatmentIndividualityObservationKinematicsMotor Activity050105 experimental psychologyNOVisual processingYoung Adult03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicinemedicineRedundancy (engineering)Humans0501 psychology and cognitive sciencesAcademicSubjects/MED00385VariabilityElectromyographyAcademicSubjects/SCI0187005 social sciencesBrainAction observationBiomechanical PhenomenaTranscranial magnetic stimulationHuman musculoskeletal systemmedicine.anatomical_structureAction (philosophy)Cortical ExcitabilityMotor unit recruitmentFemaleAcademicSubjects/MED00310Original ArticlePsychology030217 neurology & neurosurgeryAction observation Individual motor signatures Multijoint actions Transcranial magnetic stimulation VariabilityIndividual motor signaturesTranscranial magnetic stimulationCognitive psychology
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Does the Recruitment of Excitation and Inhibition in the Motor Cortex Differ?

2007

The level of excitability within the motor cortex can be described as a balance between excitation and inhibition, but it is unknown how well both processes correlate. To address this question, the authors measured motor cortical excitability and inhibition in healthy human subjects, comparing the recruitment of motor evoked potentials (MEPs) and the duration of the cortical silent period (CSP) after transcranial magnetic stimulation (TMS). Single-pulse "focal" TMS was applied at intensities varying between 90% and 200% of motor thresholds to the right motor cortex of 15 healthy volunteers. The peak-to peak size of MEP responses and the duration of the CSP were measured in small hand muscle…

AdultMaleRecruitment NeurophysiologicalPhysiologymedicine.medical_treatmentStimulationStimulus (physiology)Inhibitory postsynaptic potentialPhysiology (medical)parasitic diseasesmedicineHumansSensorimotor cortexChemistryMotor CortexNeural InhibitionMiddle AgedEvoked Potentials MotorTranscranial Magnetic StimulationTranscranial magnetic stimulationmedicine.anatomical_structureNeurologyFemaleSilent periodNeurology (clinical)NeuroscienceExcitationMotor cortexJournal of Clinical Neurophysiology
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Sacral bladder denervation for treatment of detrusor hyperreflexia and autonomic dysreflexia

2001

Objectives. Detrusor hyperreflexia after spinal cord injury may cause urinary incontinence and chronic renal failure. In patients refractory to conservative treatment and not eligible for ventral sacral root stimulation for electrically induced micturition, we investigated the therapeutic value of sacral bladder denervation as a stand-alone procedure. Methods. Nine patients (8 men and 1 woman) between 21 and 58 years old (mean 30.2) with traumatic suprasacral spinal cord lesions underwent sacral bladder denervation for treatment of detrusor hyperreflexia and/or autonomic dysreflexia. Results. Detrusor hyperreflexia and autonomic dysreflexia were eliminated in all cases. Bladder capacity inc…

AdultMaleSacrumUrologymedicine.medical_treatmentmedia_common.quotation_subjectUrinary systemUrinary BladderUrinary incontinenceQuadriplegiaurologic and male genital diseasesUrinationRhizotomyMuscle HypertoniamedicineHumansSpinal cord injurySpinal Cord Injuriesmedia_commonParaplegiaDenervationLumbar VertebraeReflex Abnormalbusiness.industryUrinary diversionMiddle Agedmedicine.diseasefemale genital diseases and pregnancy complicationsCystostomyTreatment OutcomeUrinary IncontinenceBladder augmentationAnesthesiaUrinary Tract InfectionsAutonomic DysreflexiaFemaleAutonomic dysreflexiamedicine.symptomUrinary CatheterizationbusinessFollow-Up StudiesUrology
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Chronic sacral neuromodulation for treatment of neurogenic bladder dysfunction: long-term results with unilateral implants

2001

Abstract Objectives. To investigate the therapeutic value of sacral neuromodulation in patients with neurogenic disorders in whom conservative treatment options were unsuccessful. Neurogenic disorders may result in various forms of lower urinary tract dysfunction. Methods. Twenty-seven patients (19 women, 8 men) aged 18 to 63 years (mean 44.9 years) were subjected to percutaneous test stimulation of the sacral spinal nerves. Their urologic symptoms consisted of bladder storage failure (n = 15) due to detrusor hyperreflexia and/or bladder hypersensitivity, failure to empty due to detrusor areflexia (n = 11), and combined bladder hypersensitivity and detrusor areflexia (n = 1). Twelve patient…

AdultMaleSacrummedicine.medical_specialtyPercutaneousAdolescentUrologyUrinary systemElectric Stimulation TherapyStimulationNeurological disordermedicineHumansUrinary Bladder NeurogenicNeurogenic bladder dysfunctionbusiness.industryLong term resultsMiddle AgedUrination Disordersmusculoskeletal systemmedicine.diseaseElectrodes ImplantedSurgerySacral nerve stimulationAnesthesiaFemaleImplantbusinessUrology
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